Statistics Summary Report for BSGI Center

Last updated: Mar 11 2010

• Target Status Statistics
  • Table 1: Status Statistics for BSGI
  • Table 2: Status Statistics for BSGI by Organisms
• Deposited Structure Statistics
  • Table 3: PDB Status Statistics for Structures from BSGI
  • Table 4: List of Structures Deposited by BSGI in the PDB
• Sequence Redundancy Statistics
  • Table 5: Sequence Redundancy Statistics for BSGI by Experimental Status
  • Table 6: Sequence Redundancy Statistics for Structures Released by BSGI in the PDB by Year

Target Status Statistics

Total number of targets deposited by BSGI to TargetDB: 1828

      View BSGI Target List

Table 1: Status Statistics for BSGI

Status	Total Number of Targets	(%) Relative to "Cloned" Targets	(%) Relative to "Expressed" Targets	(%) Relative to "Purified" Targets	(%) Relative to "Crystallized" Targets
Cloned	1319	100.0	-	-	-
Expressed	889	67.4	100.0	-	-
Soluble	461	35.0	51.9	-	-
Purified	488	37.0	54.9	100.0	-
Crystallized	144	10.9	16.2	29.5	100.0
Diffraction-quality Crystals	75	5.7	8.4	15.4	52.1
Diffraction	0	0.0	0.0	0.0	0.0
NMR Assigned	0	0.0	0.0	0.0	-
HSQC	22	1.7	2.5	4.5	-
Crystal Structure	57	4.3	6.4	11.7	39.6
NMR Structure	11	0.8	1.2	2.3	-
In PDB1	60	4.5	6.7	12.3	35
Work Stopped	249	-	-	-	-
Test Target	0	-	-	-	-
Other	0	-	-	-	-

Last updated: Mar 11 2010

Table 2: Status Statistics for BSGI by Organism

These statistics are derived from mapping of target sequences to GenBank using >=98% sequence identity cut off

Organism	Total Number1	Work Stopped	Cloned	Expressed	Purified	Crystallized	Crystal Structure	NMR Structure	In PDB2
Viruses	17	2	13	8	1	0	0	0	0
Archaea	20	10	5	5	4	1	1	0	1
Bacteria	1775	239	1305	883	484	143	56	11	59
Prokaryota	1795	249	1310	888	488	144	57	11	60
Yeast	21	0	0	0	0	0	0	0	0
Leishmania	2	0	2	0	0	0	0	0	0
Eukaryota	36	6	9	5	4	1	0	0	0
Uncultured or unidentified	14	3	9	3	3	0	0	0	0

Last updated: Mar 11 2010

Note 1:   Total counts in this table may differ from total number of targets and structures. A target is counted in different organism specifications if:
- a target is mapped to different organisms
- a targtet is a hybrid complex (for example:a complex of human and mouse polypeptides)

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Deposited Structure Statistics for BSGI Center

Number of Released X-Ray Structures: 47

Number of Released NMR Structures: 8

Total number of released structures from BSGI center in the PDB: 55

Table 3: PDB Status Statistics for Structures from BSGI

PDB Status	Number of Structures
Total Deposited	56
Released	55
Release on Publication	1
Release on Certain Date	0
In Process	0

Last updated: Mar 11 2010

Note 1:   "Total Deposited" are all structures in the PDB including structures released to the public and structures that are in the process to be released("Released on Publication" , "Released on Certain Date", etc.).

Table 4: List of Structures Deposited in the PDB by BSGI

Total number of structures: 57

Structures of distinct targets: 571

1   A target may reference several PDB IDs (example: structure of the same polypeptides with different ligands).
In this case only one structure is counted to compute number of structures of distinct targets

Related PDB_ID(s): PDB_ID(s) associated with the same target in targetDB

PDB_ID	Title	Target_id	Deposition Date	Released Date	PDB Status	Related PDB_ID in TargetDB
3EPS	the crystal structure of isocitrate dehydrogenase kinase/phosphatase from e. coli	ACEK_ECO57	2008-09-29	0000-00-00	HPUB	none
1SBZ	crystal structure of dodecameric fmn-dependent ubix-like decarboxylase from escherichia coli o157:h7	PAD1_ECO57	2004-02-11	2004-10-26	REL	none
2AMJ	crystal structure of modulator of drug activity b from escherichia coli o157:h7	MDAB_ECO57	2005-08-09	2006-07-18	REL	none
1LKZ	crystal structure of d-ribose-5-phosphate isomerase (rpia) from escherichia coli.	RPIA_ECOLI	2002-04-26	2002-05-08	REL	none
1NT4	crystal structure of escherichia coli periplasmic glucose-1-phosphatase h18a mutant complexed with glucose-1-phosphate	AGP_ECOLI	2003-01-28	2004-01-13	REL	none
2FLO	crystal structure of exopolyphosphatase (ppx) from e. coli o157:h7	PPX_ECO57	2006-01-06	2006-06-06	REL	none
2FSU	crystal structure of the phnh protein from escherichia coli	PHNH_ECOLI	2006-01-23	2007-03-27	REL	none
1FC4	2-amino-3-ketobutyrate coa ligase	KBL_ECOLI	2000-07-17	2001-05-02	REL	none
2D40	crystal structure of z3393 from escherichia coli o157:h7	Z3393_ECO57	2005-10-05	2006-09-26	REL	none
1TQ5	crystal structure of yhhw from escherichia coli	YHHW_ECOLI	2004-06-16	2005-06-14	REL	none
3B8N	structure of fepe- bacterial polysaccharide co-polymerase	FEPE_ECO57	2007-11-01	2008-01-22	REL	none
1Y00	solution structure of the carbon storage regulator protein csra	CSRA_ECOLI	2004-11-13	2005-06-21	REL	none
2B59	the type ii cohesin dockerin complex	CIPA_CLOTM NON-BSGI:P71143_CLOTM	2005-09-27	2005-10-11	REL	none
1GZ0	23s ribosomal rna g2251 2'o-methyltransferase rlmb	RLMB_ECOLI	2002-05-03	2002-10-17	REL	none
3B8O	structure of wzze- bacterial polysaccharide co-polymerase	WZZE_ECO57	2007-11-01	2008-01-22	REL	none
2FT0	crystal structure of tdp-fucosamine acetyltransferase (wecd)- complex with acetyl-coa	WECD_ECOL6	2006-01-23	2006-08-01	REL	none
1XK7	crystal structure- c2 form- of escherichia coli crotonobetainyl-coa: carnitine coa transferase (caib)	CAIB_ECOLI	2004-09-27	2005-03-15	REL	none
1ZPS	crystal structure of methanobacterium thermoautotrophicum phosphoribosyl-amp cyclohydrolase hisi	HIS3_METTH	2005-05-17	2005-08-30	REL	none
1K75	the l-histidinol dehydrogenase (hisd) structure implicates domain swapping and gene duplication.	HISX_ECOLI	2001-10-18	2002-02-27	REL	none
1RRZ	solution structure of glgs protein from e. coli	GLGS_ECOLI	2003-12-09	2004-06-01	REL	none
2OVI	structure of the heme binding protein chux	CHUX_ECO57	2007-02-13	2008-02-12	REL	none
1KON	crystal structure of e.coli yebc	YEBC_ECOLI	2001-12-21	2002-07-17	REL	none
1FC5	crystal structure of molybdopterin biosynthesis moea protein	MOEA_ECOLI	2000-07-17	2001-07-25	REL	none
1R6Y	crystal structure of ygin from escherichia coli	YGIN_ECOLI	2003-10-17	2004-11-02	REL	none
1U9T	crystal structure analysis of chus, an e. coli heme oxygenase	CHUS_ECO57	2004-08-10	2005-10-25	REL	none
3G2Q	crystal structure of the glycopeptide n-methyltransferase mtfa complexed with sinefungin	MTFA_AMYOR	2009-01-31	2009-05-05	REL	none
1U5W	crystal structure of hypothetical protein yjjx from escherichia coli	YJJX_ECOLI	2004-07-28	2005-08-23	REL	none
2OZN	the cohesin-dockerin complex of nagj and nagh from clostridium perfringens	Cohesin NON-BSGI:FivarDoc	2007-02-26	2008-05-06	REL	none
1ZYL	crystal structure of hypothetical protein yihe from escherichia coli	RDOA_ECOLI	2005-06-10	2006-09-19	REL	none
3G05	crystal structure of n-terminal domain (2-550) of e.coli mnmg	MNMG_ECO57	2009-01-27	2009-10-20	REL	none
2R1A	crystal structure of the periplasmic lipopolysaccharide transport protein lpta (yhbn), trigonal form	YHBN_ECOLI	2007-08-22	2008-04-29	REL	none
1PTM	crystal structure of e.coli pdxa	PDXA_ECOLI	2003-06-23	2003-11-04	REL	none
1N3B	crystal structure of dephosphocoenzyme a kinase from escherichia coli	COAE_ECOLI	2002-10-25	2003-01-28	REL	none
1FG7	crystal structure of l-histidinol phosphate aminotransferase with pyridoxal-5'-phosphate	HIS8_ECOLI	2000-07-28	2001-08-22	REL	none
2H7A	nmr structure of the conserved protein ycgl from escherichia coli representing the duf709 family reveals a novel a/b/a sandwich fold	YCGL_ECOL6	2006-06-01	2007-04-17	REL	none
1TVM	nmr structure of enzyme gatb of the galactitol-specific phosphoenolpyruvate-dependent phosphotransferase system	PTKB_ECO57	2004-06-29	2005-09-06	REL	none
1MC3	crystal structure of rffh	RMLA2_ECOLI	2002-08-05	2002-11-20	REL	none
1SG7	nmr solution structure of the putative cation transport regulator chab	CHAB_ECO57	2004-02-23	2005-03-08	REL	none
1O9B	quinate/shikimate dehydrogenase ydib complexed with nadh	YDIB_ECOLI	2002-12-12	2003-02-01	REL	none
3BE6	crystal structure of fite (crystal form 2), a group iii periplasmic siderophore binding protein	FITE_ECO57	2007-11-16	2008-10-28	REL	none
3B8P	fragment of wzzb, polysaccharide co-polymerase from salmonella typhimurium	WZZB_SALTY NON-BSGI:WZZB_ECO57	2007-11-01	2008-01-22	REL	none
1YQC	crystal structure of ureidoglycolate hydrolase (alla) from escherichia coli o157:h7	ALLA_ECO57	2005-02-01	2005-10-18	REL	none
1Q18	crystal structure of e.coli glucokinase (glk)	GLK_ECO57	2003-07-18	2004-07-27	REL	none
1L1P	solution structure of the ppiase domain from e. coli trigger factor	TIG_ECOLI	2002-02-19	2003-06-24	REL	none
1KK9	crystal structure of e. coli ycio	YCIO_ECOLI	2001-12-06	2002-12-11	REL	none
3CQJ	crystal structure of l-xylulose-5-phosphate 3-epimerase ulae (form b) complex with zn2+	ULAE_ECO57	2008-04-03	2008-11-25	REL	none
1XZO	identification of a disulfide switch in bssco, a member of the sco family of cytochrome c oxidase assembly proteins	YPMQ_BACSU	2004-11-12	2005-03-01	REL	none
1YNI	crystal structure of n-succinylarginine dihydrolase, astb, bound to substrate and product, an enzyme from the arginine catabolic pathway of escherichia coli	ASTB_ECOLI	2005-01-24	2005-02-15	REL	none
1KSL	structure of rsua	RSUA_ECOLI	2002-01-13	2002-04-24	REL	none
1PRZ	crystal structure of pseudouridine synthase rlud catalytic module	RLUD_ECO57	2003-06-20	2003-11-04	REL	none
2FPU	crystal structure of the n-terminal domain of e.coli hisb- complex with histidinol	HIS7_ECO57	2006-01-17	2006-09-05	REL	none
2AHW	crystal structure of acyl-coa transferase from e. coli o157:h7 (ydif)-thioester complex with coa- 2	YDIF_ECO57	2005-07-28	2005-11-01	REL	none
1P9K	the solution structure of ybcj from e. coli reveals a recently discovered alfal motif involved in rna-binding	YBCJ_ECOLI	2003-02-20	2003-03-11	REL	none
1SG5	solution structure of yaeo, a rho-specific inhibitor of transcription termination	ROF_ECOLI	2004-02-23	2005-07-12	REL	none
1P9N	crystal structure of escherichia coli mobb.	MOBB_ECOLI	2003-05-12	2003-05-20	REL	none
2I6R	crystal structure of e. coli hype, a hydrogenase maturation protein	HYPE_ECO57	2006-08-29	2007-10-23	REL	none
2F79	solution structure of napd a pathway specific chaperone in napa maturation	NAPD_ECOLI	2005-11-30	0000-00-00	WDRN	none

Note 1:  Last updated: Mar 11 2010

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Sequence Redundancy Statistics

Table 5: Sequence Redundancy Statistics for BSGI by Experimental Status

Sequence Identity(%)	Novel Targets Status: Selected	Novel Targets Status: Cloned	Novel Targets Status: Expressed	Novel Targets Status: Purified	Novel Targets Status: Crystallized	Novel Targets Status: Crystal Structure	Novel Targets Status: NMR Structure	Novel Targets Status: in PDB
<100	1684	1278	864	473	139	56	11	60
<90	1492	1188	813	458	134	55	10	60
<70	1459	1168	798	454	133	54	10	59
<50	1416	1137	783	447	132	54	10	59
<30	1121	966	694	412	127	54	10	59

Last updated: 10-03-08

Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in TargetDB which are in the same experimental status category and at least 20 amino acids long

Table 6:Sequence Redundancy Statistics for Structures Released by BSGI by Year

Year	Released Structures	Number of Released Structures <30% Identity at Time of Release	Percent(%) of Released Structures <30% Identity(%) at Time of Release
2001	3	0	0
2002	7	2	29
2003	7	2	29
2004	5	3	60
2005	14	5	36
2006	6	3	50
2007	3	1	33
2008	8	2	25
2009	2	0	0
Total	55	18	33

Last updated:10-03-11

Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in the PDB which are at least 20 amino acids long

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