PSI TargetDB

Statistics Summary Report for CESG Center

Last updated: Mar 11 2010



Target Status Statistics

Total number of targets deposited by CESG to TargetDB: 8773

      View CESG Target List

Table 1: Status Statistics for CESG

Status Total Number of Targets(%) Relative to "Cloned" Targets(%) Relative to "Expressed" Targets(%) Relative to "Purified" Targets(%) Relative to "Crystallized" Targets
Cloned8006100.0---
Expressed343442.9100.0--
Soluble237529.769.2--
Purified6968.720.3100.0-
Crystallized1832.35.326.3100.0
Diffraction-quality Crystals791.02.311.443.2
Diffraction841.02.412.145.9
NMR Assigned380.51.15.5-
HSQC801.02.311.5-
Crystal Structure861.12.512.447.0
NMR Structure390.51.15.6-
In PDB11231.53.617.746
Work Stopped7348----
Test Target81----
Other7636----

Last updated: Mar 11 2010

Table 2: Status Statistics for CESG by Organism

These statistics are derived from mapping of target sequences to GenBank using >=98% sequence identity cut off

Organism Total Number1 Work Stopped Cloned Expressed Purified Crystallized Crystal Structure NMR Structure In PDB2
Viruses3924242362112
Archaea101000000
Bacteria25691155323
Prokaryota266101155323
Yeast56335333132202
Plasmodium176161962520000
Trypanosoma200010000
Arabidopsis398738333686101124079341752
Rice1221191175094101
Worm1611151030011
Drosophila161013512101
Mouse128110241228708161276512
Human27581832249414492735121827
Eukaryota82736961755632196611737935114
Uncultured or unidentified110111000

Last updated: Mar 11 2010

Note 1:   Total counts in this table may differ from total number of targets and structures. A target is counted in different organism specifications if:
- a target is mapped to different organisms
- a targtet is a hybrid complex (for example:a complex of human and mouse polypeptides)

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Deposited Structure Statistics for CESG Center

Number of Released X-Ray Structures: 99

Number of Released NMR Structures: 45

Total number of released structures from CESG center in the PDB: 144

Table 3: PDB Status Statistics for Structures from CESG

PDB StatusNumber of Structures
Total Deposited145
Released144
In Process1
Last updated: Mar 11 2010
Note 1:   "Total Deposited" are all structures in the PDB including structures released to the public and structures that are in the process to be released("Released on Publication" , "Released on Certain Date", etc.).

Table 4: List of Structures Deposited in the PDB by CESG

Total number of structures: 145

Structures of distinct targets: 1221

1   A target may reference several PDB IDs (example: structure of the same polypeptides with different ligands).
In this case only one structure is counted to compute number of structures of distinct targets

Related PDB_ID(s): PDB_ID(s) associated with the same target in targetDB

PDB_ID TitleTarget_id Deposition DateReleased Date PDB StatusRelated PDB_ID in TargetDB
2KTO spatial structure of lch-beta peptide from two-component lantibiotic lichenicidin vk21GO.1032852010-02-050000-00-00PROCnone
2JMU nmr structure of the mouse thiamine triphosphataseGO.345172006-12-052006-12-19RELnone
2NXF crystal structure of a dimetal phosphatase from danio rerio loc 393393GO.706532006-11-172006-12-12RELnone
2GCU x-ray structure of gene product from arabidopsis thaliana at1g53580GO.49802006-03-142006-04-18RELnone
3IAU the structure of the processed form of threonine deaminase isoform 2 from solanum lycopersicumGO.1025082009-07-142009-07-28RELnone
2I9Y solution structure of arabidopsis thaliana protein at1g70830, a member of the major latex protein familyGO.743652006-09-062006-09-19RELnone
2IL4 crystal structure of at1g77540-coenzyme a complexGO.60422006-03-152006-03-28RELnone
1XO3 solution structure of ubiquitin like protein from mus musculusGO.341982004-10-052004-10-19RELnone
1YDU solution nmr structure of at5g01610, an arabidopsis thaliana protein containing duf538 domainGO.243152004-12-262005-02-15RELnone
2NYI crystal structure of an unknown protein from galdieria sulphurariaGO.800042006-11-202006-12-12RELnone
2FB7 nmr solution structure of protein from zebra fish dr.13312GO.708752005-12-082005-12-27RELnone
1Z7X x-ray structure of human ribonuclease inhibitor complexed with ribonuclease iGO.74361 CESG:GO.786232005-03-282005-06-21RELnone
1XRI x-ray structure of a putative phosphoprotein phosphatase from arabidopsis thaliana gene at1g05000GO.6052004-10-142004-10-26RELnone
2ATF x-ray structure of cysteine dioxygenase type i from mus musculus mm.241056GO.356832005-08-242005-10-18RELnone
1XQ1 x-ray structure of putative tropinone reducatse from arabidopsis thaliana gene at1g07440GO.23032004-10-112004-10-19RELnone
1Z84 x-ray structure of galt-like protein from arabidopsis thaliana at5g18200GO.231692005-03-292005-04-19REL1ZWJ 2H39
2Q32 crystal structure of human heme oxygenase-2 c127a (ho-2)GO.912652007-05-292007-06-05REL2QPP 2RGZ
3H7K crystal structure of arabidopsis thaliana agmatine deiminase complexed with a covalently bound reaction intermediateGO.246742009-04-272009-05-26RELnone
2K0S solution nmr structure of protein bc066483GO.721942008-02-142008-03-25RELnone
2QPP crystal structure of human heme oxygenase-2 c127a (ho-2) with bound hemeGO.912652007-07-242007-08-07RELnone
2RGZ ensemble refinement of the protein crystal structure of human heme oxygenase-2 c127a (ho-2) with bound hemeGO.912652007-10-052007-10-23RELnone
2JZ4 putative 32 kda myrosinase binding protein at3g16450.1 from arabidopsis thalianaGO.127982007-12-282008-02-19RELnone
3CAZ crystal structure of a bar protein from galdieria sulphurariaGO.800552008-02-202008-03-04RELnone
3DCY crystal structure a tp53-induced glycolysis and apoptosis regulator protein from homo sapiens.GO.405662008-06-042008-07-15RELnone
2G06 x-ray structure of mouse pyrimidine 5'-nucleotidase type 1, with bound magnesium(ii)GO.364142006-02-112006-04-04RELnone
1YCN x-ray structure of annexin from arabidopsis thaliana gene at1g35720GO.40202004-12-222005-01-04RELnone
2K2N solution structure of a cyanobacterial phytochrome gaf domain in the red light-absorbing ground stateGO.1027062008-04-042008-09-23RELnone
2A33 x-ray structure of a lysine decarboxylase-like protein from arabidopsis thaliana gene at2g37210GO.97332005-06-232005-07-19RELnone
2AB1 x-ray structure of gene product from homo sapiens hs.95870GO.337592005-07-142005-07-26RELnone
2G2B nmr structure of the human allograft inflammatory factor 1GO.337802006-02-152006-02-28RELnone
1YBM x-ray structure of selenomethionyl gene product from arabidopsis thaliana at5g02240 in space group p21212GO.236622004-12-212005-01-18RELnone
1YDW x-ray structure of gene product from arabidopsis thaliana at4g09670GO.198122004-12-262005-01-11RELnone
1VM9 the x-ray structure of the cys84ala cys85ala double mutant of the [2fe-2s] ferredoxin subunit of toluene-4-monooxygenase from pseudomonas mendocina kr1GO.346602004-09-132004-09-21RELnone
2BDU x-ray structure of a cytosolic 5'-nucleotidase iii from mus musculus mm.158936GO.364142005-10-202005-11-01REL2G06 2G07 2G08 2G0A
2EVN nmr solution structures of at1g77540GO.60422004-10-052004-10-12RELnone
2I5T crystal structure of hypothetical protein loc79017 from homo sapiensGO.352232006-08-252006-09-12RELnone
1Q45 12-0xo-phytodienoate reductase isoform 3GO.82102003-08-012003-11-25REL2G5W
2G0Q solution structure of at5g39720.1 from arabidopsis thalianaGO.224462006-02-132006-02-28RELnone
1XMT x-ray structure of gene product from arabidopsis thaliana at1g77540GO.60422004-10-042004-10-12REL2EVN 2IL4
3KEV x-ray crystal structure of a dcun1 domain-containing protein from galdieria sulfurariaGO.883442009-10-262009-12-01RELnone
1ZXU x-ray structure of protein from arabidopsis thaliana at5g01750GO.245562005-06-082005-06-21RELnone
1TIZ solution structure of a calmodulin-like calcium-binding domain from arabidopsis thalianaGO.339092004-06-022004-08-10RELnone
3I5S crystal structure of pi3k sh3GO.801602009-07-062010-03-02RELnone
2GM3 crystal structure of an universal stress protein family protein from arabidopsis thaliana at3g01520 with amp boundGO.129222006-04-052006-04-18RELnone
1XM8 x-ray structure of glyoxalase ii from arabidopsis thaliana gene at2g31350GO.96392004-10-012004-10-12RELnone
1RJJ solution structure of a homodimeric hypothetical protein, at5g22580, a structural genomics target from arabidopsis thalianaGO.229972003-11-192003-12-09RELnone
2GU2 crystal structure of an aspartoacylase from rattus norvegicusGO.596162006-04-282006-06-20RELnone
2EXR x-ray structure of cytokinin oxidase/dehydrogenase (ckx) from arabidopsis thaliana at5g21482GO.295442005-11-082005-11-29RELnone
3IHR crystal structure of uch37GO.412962009-07-302009-08-11RELnone
1XMB x-ray structure of iaa-aminoacid hydrolase from arabidopsis thaliana gene at5g56660GO.222072004-10-012004-10-12RELnone
1VKP x-ray structure of gene product from arabidopsis thaliana at5g08170, agmatine iminohydrolaseGO.246742004-06-152004-08-17REL2Q3U 3H7C 3H7K
2ICY crystal structure of a putative udp-glucose pyrophosphorylase from arabidopsis thaliana with bound udp-glucoseGO.149142006-09-132006-10-03RELnone
2IFU crystal structure of a gamma-snap from danio rerioGO.793612006-09-212006-10-10RELnone
2I3F crystal structure of a glycolipid transfer-like protein from galdieria sulphurariaGO.800172006-08-182006-08-29RELnone
1SE9 structure of at3g01050, a ubiquitin-fold protein from arabidopsis thalianaGO.151762004-02-162004-02-24RELnone
1XO8 solution structure of at1g01470 from arabidopsis thalianaGO.23612004-10-062004-10-19RELnone
2FFT nmr structure of spinach thylakoid soluble phosphoprotein of 9 kda in sds micellesGO.788552005-12-202006-01-17RELnone
3KDF x-ray crystal structure of the human replication protein a complex from wheat germ cell free expressionGO.102545 CESG:GO.1025442009-10-222009-12-01RELnone
2BEI x-ray structure of thialysine n-acetyltransferase (ssat2) from homo sapiensGO.367312005-10-242005-11-01RELnone
2GKC structural insight into self-sacrifice mechanism of enediyne resistanceGO.797512006-04-012006-08-22RELnone
2GOW solution structure of bc059385 from homo sapiensGO.351562006-04-142006-04-25RELnone
1Z90 x-ray structure of gene product from arabidopsis thaliana at3g03250, a putative udp-glucose pyrophosphorylaseGO.149142005-03-312005-04-12REL2ICX 2ICY
2JWN solution nmr structure of the protease-resistent domain of xenopus laevis epabp2GO.801822007-10-162007-10-30RELnone
2G08 x-ray structure of mouse pyrimidine 5'-nucleotidase type 1, product-transition complex analog with aluminum fluorideGO.364142006-02-112006-04-04RELnone
1VK5 x-ray structure of gene product from arabidopsis thaliana at3g22680GO.139742004-05-062004-05-18REL3GAN
1Q44 crystal structure of an arabidopsis thaliana putative steroid sulphotransferaseGO.73122003-08-012003-11-25RELnone
2G0A x-ray structure of mouse pyrimidine 5'-nucleotidase type 1 with lead(ii) bound in active siteGO.364142006-02-112006-04-04RELnone
2BE4 x-ray structure an ef-hand protein from danio rerio dr.36843GO.740732005-10-212005-11-01RELnone
1T0Y solution structure of a ubiquitin-like domain from tubulin-binding cofactor bGO.33910 SECSG:F53F4.32004-04-132004-04-27RELnone
2O57 crystal structure of a putative sarcosine dimethylglycine methyltransferase from galdieria sulphurariaGO.800482006-12-052006-12-19RELnone
2A3Q x-ray structure of protein from mus musculus mm.29898GO.344552005-06-252005-07-19RELnone
1VM0 x-ray structure of gene product from arabidopsis thaliana at2g34160GO.87932004-08-242004-08-31RELnone
1YDH x-ray structure of a lysine decarboxylase-like protein from arabidopsis thaliana gene at5g11950GO.199122004-12-232005-01-11RELnone
2JQV solution structure at3g28950.1 from arabidopsis thalianaGO.162112007-06-072007-08-14RELnone
2G07 x-ray structure of mouse pyrimidine 5'-nucleotidase type 1, phospho-enzyme intermediate analog with beryllium fluorideGO.364142006-02-112006-04-04RELnone
3BZB crystal structure of uncharacterized protein cmq451c from the primitive red alga cyanidioschyzon merolaeGO.814002008-01-172008-01-29RELnone
3G5T crystal structure of trans-aconitate 3-methyltransferase from yeastGO.932352009-02-052009-03-03RELnone
2QU1 crystal structure of a cyclized gfp variantGO.915712007-08-032007-09-11RELnone
2GKD structural insight into self-sacrifice mechanism of enediyne resistanceGO.797512006-04-012006-08-22RELnone
1XY7 x-ray structure of gene product from arabidopsis thaliana at5g48480GO.223402004-11-092004-11-16RELnone
3D89 crystal structure of a soluble rieske ferredoxin from mus musculusGO.358792008-05-222008-07-15RELnone
2QNK crystal structure of human 3-hydroxyanthranilate 3,4-dioxygenaseGO.433162007-07-182007-08-14RELnone
3BVO crystal structure of human co-chaperone protein hscbGO.912962008-01-072008-01-15RELnone
2JYC nmr solution structure of human protein c6orf130, a putative macro domainGO.367282007-12-122008-01-08RELnone
3IA8 the structure of the c-terminal heme nitrobindin domain of thap domain-containing protein 4 from homo sapiensGO.1024072009-07-132009-07-28RELnone
2F2G x-ray structure of gene product from arabidopsis thaliana at3g16990GO.122402003-08-042003-11-25RELnone
2KQR solution structure of the n-terminal domain (residues 1-111) of brugia malayi asparaginyl-trna synthetaseGO.1020662009-11-162009-12-15RELnone
1XYG x-ray structure of gene product from arabidopsis thaliana at2g19940GO.93832004-11-092004-11-23RELnone
1YVI x-ray structure of putative histidine-containing phosphotransfer protein from rice, ak104879GO.339572005-02-152005-02-22RELnone
2A3L x-ray structure of adenosine 5'-monophosphate deaminase from arabidopsis thaliana in complex with coformycin 5'-phosphateGO.116482005-06-252005-07-19RELnone
1XQ5 met-perch hemoglobin at 1.9aGO.343682004-10-112004-11-16RELnone
1YYC solution structure of a putative late embryogenesis abundant (lea) protein at2g46140.1GO.99432005-02-242005-04-05RELnone
3GAN crystal structure of gene product from arabidopsis thaliana at3g22680 with bound suraminGO.139742009-02-172009-03-03RELnone
2G5W x-ray crystal structure of arabidopsis thaliana 12-oxophytodienoate reductase isoform 3 (atopr3) in complex with 8-iso prostaglandin a1 and its cofactor, flavin mononucleotide.GO.82102006-02-232006-04-04RELnone
2ETT solution structure of human sorting nexin 22 px domainGO.338112005-10-272005-11-15RELnone
1ZVC x-ray structure of allene oxide cyclase from arabidopsis thaliana at3g25760GO.158382005-06-012005-06-14RELnone
3BOM crystal structure of trout hemoglobin at 1.35 angstrom resolutionGO.97349 CESG:GO.973482007-12-172008-01-08RELnone
2A13 x-ray structure of protein from arabidopsis thaliana at1g79260GO.64622005-06-172005-07-12REL3EMM
2GW6 nmr structure of the human trna endonuclease sen15 subunitGO.788562006-05-032006-05-16RELnone
1VJH crystal structure of gene product of at1g24000 from arabidopsis thalianaGO.53582004-02-202004-03-16RELnone
3EMM x-ray structure of protein from arabidopsis thaliana at1g79260 with bound hemeGO.64622008-09-242008-10-14RELnone
1ZWJ x-ray structure of galt-like protein from arabidopsis thaliana at5g18200GO.231692004-06-242004-08-10RELnone
2ICX crystal structure of a putative udp-glucose pyrophosphorylase from arabidopsis thaliana with bound utpGO.149142006-09-132006-09-26RELnone
2H39 crystal structure of an adp-glucose phosphorylase from arabidopsis thaliana with bound adp-glucoseGO.231692006-03-162006-04-04RELnone
2GNX x-ray structure of a hypothetical protein from mouse mm.209172GO.343512006-04-112006-05-02RELnone
2FI2 solution structure of the scan homodimer from mzf-1/znf42GO.791322005-12-272006-01-17RELnone
1XFI x-ray structure of gene product from arabidopsis thaliana at2g17340GO.81952004-09-142004-09-28RELnone
1ZTP x-ray structure of gene product from homo sapiens hs.433573GO.367042005-05-272005-06-14RELnone
1VJI gene product of at1g76680 from arabidopsis thalianaGO.30732004-02-242004-03-16RELnone
2I3C crystal structure of an aspartoacylase from homo sapiensGO.793682006-08-172006-08-29RELnone
2I2O crystal structure of an eif4g-like protein from danio rerioGO.792942006-08-162006-08-29RELnone
1T0G hypothetical protein at2g24940.1 from arabidopsis thaliana has a cytochrome b5 like foldGO.67052004-03-282004-04-06RELnone
2APJ x-ray structure of protein from arabidopsis thaliana at4g34215 at 1.6 angstrom resolutionGO.227972005-07-212005-08-02RELnone
2JM0 solution structure of chicken villin headpiece subdomain containing a fluorinated side chain in the coreGO.1020262006-09-062006-10-17RELnone
2H1S crystal structure of a glyoxylate/hydroxypyruvate reductase from homo sapiensGO.375402006-05-162006-06-27RELnone
2KMW solution structure of at3g03773.1 protein from arabidopsis thalianaGO.131932009-08-052009-10-06RELnone
2O55 crystal structure of a putative glycerophosphodiester phosphodiesterase from galdieria sulphurariaGO.800342006-12-052006-12-19RELnone
1XJ5 x-ray structure of spermidine synthase from arabidopsis thaliana gene at1g23820GO.38512004-09-222004-10-05RELnone
1XOY solution structure of at3g04780.1, an arabidopsis ortholog of the c-terminal domain of human thioredoxin-like proteinGO.116242004-10-072004-10-12RELnone
1TQ1 solution structure of at5g66040, a putative protein from arabidosis thalianaGO.208622004-06-162004-06-29RELnone
2HO4 crystal structure of protein from mouse mm.236127GO.345562006-07-132006-08-15RELnone
1VK0 x-ray structure of gene product from arabidopsis thaliana at5g06450GO.221162004-04-122004-04-27RELnone
1Z8K x-ray structure of allene oxide cyclase from arabidopsis thaliana at3g25770GO.158392005-03-302005-04-12RELnone
2KGQ refined solution structure of des-pyro glu brazzeinGO.915952009-03-132009-06-09RELnone
2AMY x-ray structure of human phosphomannomutase 2 (pmm2)GO.366532005-08-102005-08-23RELnone
1ZXF solution structure of a self-sacrificing resistance protein, calc from micromonospora echinosporaGO.797512005-06-082005-12-13REL2GKC 2GKD
1XFL solution structure of thioredoxin h1 from arabidopsis thalianaGO.147512004-09-152004-09-28RELnone
1JXC minimized nmr structure of att, an arabidopsis trypsin/chymotrypsin inhibitorGO.91612001-09-062003-01-07RELnone
1WVK nmr solution structure of the partially disordered protein at2g23090 from arabidopsis thalianaGO.74742004-12-162005-01-04RELnone
1Q4R gene product of at3g17210 from arabidopsis thalianaGO.130812003-08-042003-11-25REL1Q53
3C9Q crystal structure of the uncharacterized human protein c8orf32 with bound peptideGO.397722008-02-182008-02-26RELnone
2Q3U ensemble refinement of the protein crystal structure of gene product from arabidopsis thaliana at5g08170, agmatine iminohydrolaseGO.246742007-05-302007-06-19RELnone
1Q53 solution structure of hypothetical arabidopsis thaliana protein at3g17210. center for eukaryotic structural genomics target 13081GO.130812003-02-062003-06-03RELnone
1ZR9 solution structure of a human c2h2-type zinc finger proteinGO.338102005-05-192005-06-07RELnone
2I5S crystal structure of onconase with bound nucleic acidGO.801602006-08-252006-09-05REL3I5S
2GOV solution structure of murine p22hbpGO.791302006-04-142006-05-09RELnone
3H7C crystal structure of arabidopsis thaliana agmatine deiminase from cell free expressionGO.246742009-04-242009-05-26RELnone
1YEL structure of the hypothetical arabidopsis thaliana protein at1g16640.1GO.339312004-12-282005-01-18RELnone
2JU4 nmr structure of the gamma subunit of cgmp phosphodiesteraseGO.817822007-08-142007-10-16RELnone
2GMK crystal structure of onconase double mutant with spontaneously-assembled (amp) 4 stackGO.801612006-04-062006-04-25RELnone
1Y0Z x-ray structure of gene product from arabidopsis thaliana at3g21360GO.131672004-11-162004-11-30RELnone
1Y4O solution structure of a mouse cytoplasmic roadblock/lc7 dynein light chainGO.343822004-12-012005-01-18RELnone
2BAI the zinc finger domain of mengovirus leader polypeptideGO.797612005-10-142006-01-24RELnone
2GHP crystal structure of the n-terminal 3 rna binding domains of the yeast splicing factor prp24GO.743682006-03-272006-04-25RELnone
1XQ6 x-ray structure of gene product from arabidopsis thaliana at5g02240GO.236622004-10-112004-10-19REL1YBM

Note 1:  Last updated: Mar 11 2010

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Sequence Redundancy Statistics

Table 5: Sequence Redundancy Statistics for CESG by Experimental Status

Sequence Identity(%)Novel Targets
Status:
Selected
Novel Targets
Status:
Cloned
Novel Targets
Status:
Expressed
Novel Targets
Status:
Purified
Novel Targets
Status:
Crystallized
Novel Targets
Status:
Crystal Structure
Novel Targets
Status:
NMR Structure
Novel Targets
Status:
in PDB
<1008078759533198041877838116
<907646721231597701817638115
<707039666929667331697438113
<506255600027817031627337111
<305044503924806651577137108
Last updated: 10-03-08
Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in TargetDB which are in the same experimental status category and at least 20 amino acids long

Table 6:Sequence Redundancy Statistics for Structures Released by CESG by Year

Year Released Structures Number of Released Structures <30% Identity at Time of Release Percent(%) of Released Structures <30% Identity(%) at Time of Release
20037571
2004301653
2005331958
2006402153
20079111
200812650
200912433
2010100
Total1447250
Last updated:10-03-11
Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in the PDB which are at least 20 amino acids long
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