Statistics Summary Report for Structural Genomics Centers in Europe

Last updated: Mar 11 2010

|BIGS| |ISPC| |MSGP| |OPPF| |SPINE| |XMTB| |YSG| |SGC|

• Target Status Statistics
  • Table 1: Status Statistics for Structural Genomics Centers in Europe
  • Figure 1: Target Experimental Status for Structural Genomics Centers in Europe
  • Table 2: Status Statistics for Structural Genomics Centers in Europe by Organisms
  • Figure 2: Source Organisms at Structural Genomics Centers in Europe
• Deposited Structure Statistics
  • Table 3: PDB Status Statistics for Structures from Structural Genomics Centers in Europe
  • Figure 3: Structures Released by Structural Genomics Centers in Europe by Year
  • Table 4: List of Structures Deposited by Structural Genomics Centers in Europe in the PDB
• Sequence Redundancy Statistics
  • Table 5: Sequence Redundancy Statistics for Structural Genomics Centers in Europe by Experimental Status
  • Table 6: Sequence Redundancy Statistics for Structures Released by Structural Genomics Centers in Europe in the PDB by Year
  • Figure 4: Comparison of Novel Structures with Number of Structures Released by Structural Genomics Centers in Europe by Year

Target Status Statistics

Total number of targets deposited by Structural Genomics Centers in Europe to TargetDB: 3313

Table 1: Status Statistics for Structural Genomics Centers in Europe

Status	Total Number of Targets	(%) Relative to "Cloned" Targets	(%) Relative to "Expressed" Targets	(%) Relative to "Purified" Targets	(%) Relative to "Crystallized" Targets
Cloned	2440	100.0	-	-	-
Expressed	1658	68.0	100.0	-	-
Soluble	846	34.7	51.0	-	-
Purified	834	34.2	50.3	100.0	-
Crystallized	239	9.8	14.4	28.7	100.0
Diffraction-quality Crystals	148	6.1	8.9	17.7	61.9
Diffraction	95	3.9	5.7	11.4	39.7
NMR Assigned	29	1.2	1.7	3.5	-
HSQC	49	2.0	3.0	5.9	-
Crystal Structure	172	7.0	10.4	20.6	72.0
NMR Structure	28	1.1	1.7	3.4	-
In PDB1	122	5.0	7.4	14.6	40
Work Stopped	45	-	-	-	-
Test Target	1	-	-	-	-
Other	0	-	-	-	-

Last updated: Mar 11 2010
Note 1:   Number of targets with status "in PDB" may not be equal to number of structures determined by a project. A target may reference several PDB IDs (example: structure of the same polypeptides with different ligands). Multiple targets in TargetDB may identify the same PDB structure when a stucture is a result of collaboration between different centers and each center includes the target on its target list.

Figure 1: Target Experimental Status for Structural Genomics Centers in Europe

Last updated: Mar 11 2010

This graph is normalized relative to number of cloned targets in TargetDB.
Targets that progressed to status "Cloned" constitute 74% of TargetDB.

Table 2: Status Statistics for Structural Genomics Centers in Europe by Organism

These statistics is derived from mapping of target sequences to GenBank using >=98% sequence identity cut off

Organism	Total Number1	Work Stopped	Cloned	Expressed	Purified	Crystallized	Crystal Structure	NMR Structure	In PDB2
Viruses	182	1	114	50	17	7	8	0	2
Archaea	51	0	27	1	1	1	1	0	0
Bacteria	1308	17	841	664	287	122	83	11	56
Prokaryota	1359	17	868	665	288	123	84	11	56
Yeast	342	19	303	258	101	13	13	2	2
Plasmodium	8	0	1	1	1	0	0	0	0
Arabidopsis	2	0	2	2	2	1	0	0	0
Worm	2	0	1	1	1	0	0	1	1
Drosophila	20	0	12	9	4	1	0	1	1
Mouse	184	3	125	101	47	16	9	4	11
Human	590	7	375	315	139	49	30	15	32
Eukaryota	1083	26	774	651	291	87	61	17	45
Uncultured or unidentified	4	0	4	3	0	0	0	0	0

Last updated: Mar 11 2010

Note 1:   Total counts in this table may differ from total number of targets and structures. A target is counted in different organism specifications if:
- a target is mapped to different organisms
- a targtet is a hybrid complex (for example:a complex of human and mouse polypeptides)

Figure 2: Source Organisms in Structural Genomics Centers in Europe

Last updated: Mar 11 2010 back to top

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Deposited Structure Statistics for Structural Genomics Centers in Europe

Number of Released X-Ray Structures: 114

Number of Released NMR Structures: 34

Total number of released structures from Structural Genomics Centers in Europe in the PDB: 148

Table 3: PDB Status Statistics for Structures from Structural Genomics Centers in Europe

PDB Status	BIGS	ISPC	MSGP	OPPF	SPINE	XMTB	YSG	SGC	Total
Total Deposited	9	13	0	0	97	0	15	0	152
Released	8	13	0	0	94	0	15	0	148
Release on Publication	0	0	0	0	0	0	0	0	0
Release on Certain Date	0	0	0	0	0	0	0	0	0
In Process	1	0	0	0	3	0	0	0	4

Last updated: Mar 11 2010

Note 1:   "Total Deposited" are all structures in the PDB including structures released to the public and structures that are in the process to be released("Released on Publication" , "Released on Certain Date", etc.).

Note 2:  Some PDB IDs are cross referenced by different centers. Therefore difference between "Total" number of structures and direct sum of number of structures from individual centers can be observed

Figure 3: Structures Released by Structural Genomics Centers in Europe by Year

Last updated: Mar 11 2010

Table 4: List of Structures Deposited in the PDB by Structural Genomics Centers in Europe

Total number of structures: 138

Structures of distinct targets: 1051

1   A target may reference several PDB IDs (example: structure of the same polypeptides with different ligands).
In this case only one structure is counted to compute number of structures of distinct targets

Related PDB_ID(s): PDB_ID(s) associated with the same target in targetDB

PDB_ID	Title	Target_id	Deposition Date	Released Date	PDB Status	Related PDB_ID in TargetDB
ND_135	BIGS	Experimental status "in PDB", PDB ID is not provided	Pf-cal:CA1462	-	-	-	none
1UUF	BIGS	crystal structure of a zinc-type alcohol dehydrogenase-like protein yahk	ASG-yahK	2003-12-18	2004-01-29	REL	none
1OG6	BIGS	ydhf, an aldo-keto reductase from e.coli complexed with nadph	ASG-ydhF	2003-04-24	2003-05-29	REL	none
1J2R	BIGS	crystal structure of escherichia coli gene product yecd at 1.3 a resolution	ASG-yecD	2003-01-09	2004-01-27	REL	none
1OKJ	BIGS	mad crystal structure of the unknown function e. coli yeaz protein	IGS-yeaZ	2003-07-26	2004-09-16	REL	none
1GPQ	BIGS	structure of ivy complexed with its target, hewl	ORPH-ykfE	2001-11-08	2003-03-11	REL	none
1OI4	BIGS	cristal structure of yhbo from escherichia coli	ASG-yhbO	2003-06-06	2003-07-03	REL	none
1UQW	BIGS	crystal structure of ylib protein from escherichia coi	ASG-yliB	2003-10-22	2003-10-22	REL	none
1MZR	BIGS	structure of dkga from e.coli at 2.13 a resolution solved by molecular replacement	ASG-yqhE	2002-10-09	2003-10-28	REL	none
2NVB	ISPC	contribution of pro275 to the thermostability of the alcohol dehydrogenases (adhs)	W00208	2006-11-12	2007-11-13	REL	none
1ZGB	ISPC	crystal structure of torpedo californica acetylcholinesterase in complex with an (r)-tacrine(10)-hupyridone inhibitor.	W00568	2005-04-21	2005-08-16	REL	none
1ZGC	ISPC	crystal structure of torpedo californica acetylcholinesterase in complex with an (rs)-tacrine(10)-hupyridone inhibitor.	W00567	2005-04-21	2005-08-16	REL	none
1V04	ISPC	serum paraoxonase by directed evolution	W00066	2004-03-22	2004-04-23	REL	none
2F1O	ISPC	crystal structure of nqo1 with dicoumarol	W00027	2005-11-15	2006-05-16	REL	none
1OGS	ISPC	human acid-beta-glucosidase	W00186	2003-05-13	2003-07-03	REL	none
1Y7V	ISPC	x-ray structure of human acid-beta-glucosidase covalently bound to conduritol b epoxide	W00572	2004-12-10	2005-04-12	REL	none
2B5R	ISPC	1b lactamase / b lactamase inhibitor	W00364	2005-09-29	2006-04-11	REL	none
1S0W	ISPC	1b lactamse/ b lactamase inhibitor	W00187	2004-01-05	2004-02-10	REL	none
2B83	ISPC	a single amino acid substitution in the clostridium beijerinckii alcohol dehydrogenase is critical for thermostabilization	W00283	2005-10-06	2006-09-19	REL	none
1Y7W	ISPC	crystal structure of a halotolerant carbonic anhydrase from dunaliella salina	W00565	2004-12-10	2005-05-03	REL	none
1U65	ISPC	ache w. cpt-11	W00566	2004-07-29	2005-07-19	REL	none
1XXM	ISPC	the modular architecture of protein-protein binding site	W00178	2004-11-07	2005-01-18	REL	none
2OET	ISPC	crystal structure of antizyme inhibitor	W00007	2007-01-01	0000-00-00	WDRN	none
ND_154	SPINE	Experimental status "in PDB", PDB ID is not provided	CIRMMP23	-	-	-	none
1UV1	SPINE	-	CIRMMP33	-	-	-	1UV2
1UV2	SPINE	-	CIRMMP33	-	-	-	none
1USL	SPINE	structure of mycobacterium tuberculosis ribose-5-phosphate isomerase, rpib, rv2465c, complexed with phosphate.	rv2465c TB:Rv2465c	2003-11-25	2004-01-02	REL	none
1XDS	SPINE	crystal structure of aclacinomycin-10-hydroxylase (rdmb) in complex with s-adenosyl-l-methionine (sam) and 11-deoxy-beta-rhodomycin (dbra)	St_02	2004-09-08	2004-11-23	REL	none
1FCY	SPINE	isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the rarbeta/gamma-selective retinoid cd564	IGBMC-0078-000	2000-07-19	2000-09-11	REL	none
1R1K	SPINE	crystal structure of the ligand-binding domains of the heterodimer ecr/usp bound to ponasterone a	IGBMC-0090-000 NON-SPINE:IGBMC-0091-000	2003-09-24	2003-11-18	REL	1R20
2LBD	SPINE	ligand-binding domain of the human retinoic acid receptor gamma bound to all-trans retinoic acid	IGBMC-0078-000	1997-08-19	1997-11-12	REL	none
1T5C	SPINE	crystal structure of the motor domain of human kinetochore protein cenp-e	CENP-E_342	2004-05-04	2005-05-10	REL	none
1MVO	SPINE	crystal structure of the phop receiver domain from bacillus subtilis	IGBMC-1123-000	2002-09-26	2002-10-16	REL	none
1M5T	SPINE	crystal structure of the response regulator divk	IGBMC-1121-000	2002-07-10	2002-11-15	REL	1M5U 1MAV 1MB0 1MB3
1TXE	SPINE	solution structure of the active-centre mutant ile14ala of the histidine-containing phosphocarrier protein (hpr) from staphylococcus carnosus	REGEN_HPr_Sc	2004-07-04	2005-03-08	REL	none
1NM4	SPINE	solution structure of cu(i)-copc from pseudomonas syringae	CIRMMP01	2003-01-09	2003-04-08	REL	1OT4
2BZE	SPINE	nmr structure of human rtf1 plus3 domain.	BCBRA022	2005-08-16	2007-01-03	REL	none
1P6U	SPINE	nmr structure of the bef3-activated structure of the response regulator chey2-mg2+ from sinorhizobium meliloti	1	2003-04-30	2003-11-04	REL	none
2BSY	SPINE	epstein barr virus dutpase	P6-000-000-009	2005-05-24	2005-09-15	REL	2BT1
1OSC	SPINE	crystal structure of rat cuta1 at 2.15 a resolution	CIRMMP04	2003-03-19	2003-11-25	REL	none
1FCX	SPINE	isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the rargamma-selective retinoid bms184394	IGBMC-0078-000	2000-07-19	2000-09-11	REL	none
1ON4	SPINE	solution structure of soluble domain of sco1 from bacillus subtilis	CIRMMP02	2003-02-27	2003-11-11	REL	none
1SU3	SPINE	x-ray structure of human prommp-1: new insights into collagenase action	MPIB-401	2004-03-26	2004-12-21	REL	none
1SB6	SPINE	solution structure of a cyanobacterial copper metallochaperone, scatx1	CIRMMP34	2004-02-10	2004-04-27	REL	none
1KA5	SPINE	refined solution structure of histidine containing phosphocarrier protein from staphyloccocus aureus	REGEN_HPr_Sa	1995-11-20	1996-03-08	REL	none
1YCM	SPINE	solution structure of matrix metalloproteinase 12 (mmp12) in the presence of n-isobutyl-n-[4-methoxyphenylsulfonyl]glycyl hydroxamic acid (nngh)	CIRMMP48	2004-12-22	2005-04-19	REL	none
1YLK	SPINE	crystal structure of rv1284 from mycobacterium tuberculosis in complex with thiocyanate	Rv1284 TB:Rv1284	2005-01-19	2005-03-08	REL	none
1OLZ	SPINE	the ligand-binding face of the semaphorins revealed by the high resolution crystal structure of sema4d	OPTIC7164	2003-08-19	2003-09-11	REL	none
1EXX	SPINE	enantiomer discrimination illustrated by crystal structures of the human retinoic acid receptor hrargamma ligand binding domain: the complex with the inactive s-enantiomer bms270395.	IGBMC-0078-000	2000-05-05	2000-06-09	REL	none
1SJW	SPINE	structure of polyketide cyclase snoal	ST_3	2004-03-04	2004-04-27	REL	none
1TW2	SPINE	crystal structure of carminomycin-4-o-methyltransferase (dnrk) in complex with s-adenosyl-l-homocystein (sah) and 4-methoxy-e-rhodomycin t (m-et)	ST_04	2004-06-30	2004-09-14	REL	none
1OQ3	SPINE	a core mutation affecting the folding properties of a soluble domain of the atpase protein copa from bacillus subtilis	CIRMMP05	2003-03-07	2003-09-16	REL	1OQ6
1MB3	SPINE	crystal structure of the response regulator divk at ph 8.5 in complex with mg2+	IGBMC-1121-000	2002-08-02	2002-12-04	REL	none
1UWY	SPINE	crystal structure of human carboxypeptidase m	MPIB-427	2004-02-17	2004-04-08	REL	none
1TL4	SPINE	solution structure of cu(i) hah1	CIRMMP27	2004-06-09	2004-10-26	REL	1TL5
2C2I	SPINE	structure and function of rv0130, a conserved hypothetical protein from m.tuberculosis	rv0130	2005-09-29	2006-09-14	REL	none
2BF8	SPINE	crystal structure of sumo modified ubiquitin conjugating enzyme e2- 25k	SUMO	2004-12-06	2005-02-16	REL	none
1QZZ	SPINE	crystal structure of aclacinomycin-10-hydroxylase (rdmb) in complex with s-adensyl-l-methionine (sam)	St_02	2003-09-19	2003-11-25	REL	1XDS
1YJU	SPINE	solution structure of the apo form of the sixth soluble domain of menkes protein	CIRMMP28	2005-01-15	2006-01-03	REL	none
1FD0	SPINE	isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the rargamma-selective retinoid sr11254	IGBMC-0078-000	2000-07-19	2002-09-27	REL	none
1QKU	SPINE	wild type estrogen nuclear receptor ligand binding domain complexed with estradiol	IGBMC-0005-000	1999-08-05	2000-08-18	REL	none
1YUR	SPINE	solution structure of apo-s100a13 (minimized mean structure)	CIRMMP11	2005-02-14	2005-10-18	REL	none
1X9L	SPINE	solution structure of cui-dr1885 from deinococcus radiodurans	CIRMMP12	2004-08-23	2004-08-31	REL	1X7L
1BON	SPINE	three-dimensional structure of bombyxin-ii, an insulin-related brain-secretory peptide of the silkmoth bombyx mori: comparison with insulin and relaxin	AF31	1994-07-21	1995-01-26	REL	none
2BDI	SPINE	human kallikrein 4 complex with cobalt and p-aminobenzamidine	MPIB-209	2005-10-20	2006-10-03	REL	none
1S6O	SPINE	solution structure and backbone dynamics of the apo-form of the second metal-binding domain of the menkes protein atp7a	CIRMMP25	2004-01-26	2004-04-06	REL	1S6U
1W74	SPINE	x-ray structure of peptidyl-prolyl cis-trans isomerase a, ppia, rv0009, from mycobacterium tuberculosis.	rv0009	2004-08-27	2004-10-20	REL	none
4LBD	SPINE	ligand-binding domain of the human retinoic acid receptor gamma bound to the synthetic agonist bms961	IGBMC-0078-000	1998-02-04	1999-03-02	REL	none
2BMX	SPINE	mycobacterium tuberculosis ahpc	IPRv2428PALZ TB:Rv2428	2005-03-16	2005-05-10	REL	none
1RJV	SPINE	solution structure of human alpha-parvalbumin refined with a paramagnetism-based strategy	CIRMMP07	2003-11-20	2004-05-25	REL	1RK9
1YM3	SPINE	crystal structure of carbonic anhydrase rv3588c from mycobacterium tuberculosis	Rv3588	2005-01-20	2005-03-08	REL	none
1KV6	SPINE	x-ray structure of the orphan nuclear receptor err3 ligand-binding domain in the constitutively active conformation	IGBMC-0019-000	2002-01-25	2003-01-25	REL	none
1PFJ	SPINE	solution structure of the n-terminal ph/ptb domain of the tfiih p62 subunit	IGBMC-0024-000	2003-05-27	2004-06-08	REL	none
1SW8	SPINE	solution structure of the n-terminal domain of human n60d calmodulin refined with paramagnetism based strategy	CIRMMP35	2004-03-30	2004-04-06	REL	none
1QKT	SPINE	mutant estrogen nuclear receptor ligand binding domain complexed with estradiol	IGBMC-0005-000	1999-08-05	2000-08-18	REL	none
1Y3K	SPINE	solution structure of the apo form of the fifth domain of menkes protein	CIRMMP26	2004-11-25	2005-03-08	REL	none
1OQ6	SPINE	solution structure of copper-s46v copa from bacillus subtilis	CIRMMP05	2003-03-07	2003-09-16	REL	none
1EXA	SPINE	enantiomer discrimination illustrated by crystal structures of the human retinoic acid receptor hrargamma ligand binding domain: the complex with the active r-enantiomer bms270394.	IGBMC-0078-000	2000-05-02	2000-06-09	REL	1EXX 1FCX 1FCY 1FCZ 1FD0 2LBD 3LBD 4LBD
1G50	SPINE	crystal structure of a wild type her alpha lbd at 2.9 angstrom resolution	IGBMC-0005-000	2000-10-30	2002-02-06	REL	1QKT 1QKU
1XA3	SPINE	crystal structure of caib, a type iii coa transferase in carnitine metabolism	AD59	2004-08-25	2004-11-16	REL	none
1UB1	SPINE	solution structure of the matrix attachment region-binding domain of chicken mecp2	3	2003-03-27	2003-08-05	REL	none
1YJR	SPINE	solution structure of the apo form of the sixth soluble domain a69p mutant of menkes protein	CIRMMP29	2005-01-15	2006-01-03	REL	none
1Q0Z	SPINE	crystal structure of aclacinomycin methylesterase (rdmc) with bound product analogue, 10-decarboxymethylaclacinomycin a (dcma)	St_1	2003-07-18	2003-11-25	REL	none
2BEP	SPINE	crystal structure of ubiquitin conjugating enzyme e2-25k	Hip2	2004-11-29	2005-02-16	REL	none
2BDG	SPINE	human kallikrein 4 complex with nickel and p-aminobenzamidine	MPIB-209	2005-10-20	2006-10-03	REL	2BDH 2BDI
1ZJ8	SPINE	structure of mycobacterium tuberculosis nira protein	Mtb1 TB:Rv2391	2005-04-28	2005-05-31	REL	none
1FCZ	SPINE	isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the panagonist retinoid bms181156	IGBMC-0078-000	2000-07-19	2000-09-11	REL	none
1UVQ	SPINE	crystal structure of hla-dq0602 in complex with a hypocretin peptide	OPTIC7172	2004-01-22	2004-02-05	REL	none
1YJE	SPINE	crystal structure of the rngfi-b ligand-binding domain	IGBMC-1013-000	2005-01-14	2005-02-22	REL	none
1MAV	SPINE	crystal structure of the response regulator divk at ph 6.0 in complex with mn2+	IGBMC-1121-000	2002-08-02	2002-12-04	REL	none
3LBD	SPINE	ligand-binding domain of the human retinoic acid receptor gamma bound to 9-cis retinoic acid	IGBMC-0078-000	1998-02-04	1999-03-02	REL	none
1SZW	SPINE	crystal structure of e. coli trna pseudouridine synthase trud	AF46	2004-04-06	2004-04-20	REL	none
1UOS	SPINE	the crystal structure of the snake venom toxin convulxin	OX_CVX	2003-09-22	2003-10-14	REL	none
1LBD	SPINE	ligand-binding domain of the human nuclear receptor rxr-alpha	IGBMC-0017-000	1996-05-22	1996-11-08	REL	none
2BDH	SPINE	human kallikrein 4 complex with zinc and p-aminobenzamidine	MPIB-209	2005-10-20	2006-10-03	REL	none
1P6Q	SPINE	nmr structure of the response regulator chey2 from sinorhizobium meliloti, complexed with mg++	1	2003-04-30	2004-06-15	REL	1P6U
1TTX	SPINE	solution stucture of human beta parvalbumin (oncomodulin) refined with a paramagnetism based strategy	CIRMMP08	2004-06-23	2005-01-18	REL	none
2BT1	SPINE	epstein barr virus dutpase in complex with a,b-imino dutp	P6-000-000-009	2005-05-24	2005-09-15	REL	none
1S6U	SPINE	solution structure and backbone dynamics of the cu(i) form of the second metal-binding domain of the menkes protein atp7a	CIRMMP25	2004-01-27	2004-04-06	REL	none
1O6Y	SPINE	catalytic domain of pknb kinase from mycobacterium tuberculosis	IPRv0014cPALZ TB:Rv0014c	2002-10-21	2003-01-30	REL	none
1SO9	SPINE	solution structure of apocox11, 30 structures	CIRMMP18	2004-03-13	2004-08-10	REL	none
1P6T	SPINE	structure characterization of the water soluble region of p-type atpase copa from bacillus subtilis	CIRMMP06	2003-04-30	2003-12-16	REL	none
1OT4	SPINE	solution structure of cu(ii)-copc from pseudomonas syringae	CIRMMP01	2003-03-21	2003-07-08	REL	none
2BNG	SPINE	structure of an m.tuberculosis leh-like epoxide hydrolase	rv2740	2005-03-24	2005-08-03	REL	none
1DKF	SPINE	crystal structure of a heterodimeric complex of rar and rxr ligand-binding domains	IGBMC-0012-000	1999-12-07	2000-04-19	REL	none
1O6E	SPINE	epstein-barr virus protease	P6-000-000-014	2002-09-13	2002-11-14	REL	none
1TL5	SPINE	solution structure of apohah1	CIRMMP27	2004-06-09	2004-10-26	REL	none
1MB0	SPINE	crystal structure of the response regulator divk at ph 8.0 in complex with mn2+	IGBMC-1121-000	2002-08-02	2002-12-04	REL	none
1NAQ	SPINE	crystal structure of cuta1 from e.coli at 1.7 a resolution	CIRMMP03	2002-11-28	2003-11-25	REL	none
1M5U	SPINE	crystal structure of the response regulator divk. structure at ph 8.0 in the apo-form	IGBMC-1121-000	2002-07-10	2002-11-15	REL	none
1G2N	SPINE	crystal structure of the ligand binding domain of the ultraspiracle protein usp, the ortholog of rxrs in insects	IGBMC-0091-000	2000-10-20	2001-04-21	REL	1R1K 1R20
2BI0	SPINE	x-ray structure of a conserved hypothetical protein, rv0216, from mycobacterium tuberculosis.	rv0216 TB:Rv0216	2005-01-20	2005-04-25	REL	none
1Q0R	SPINE	crystal structure of aclacinomycin methylesterase (rdmc) with bound product analogue, 10-decarboxymethylaclacinomycin t (dcmat)	St_1	2003-07-17	2003-11-25	REL	1Q0Z
1W6V	SPINE	solution structure of the dusp domain of husp15	BCBRA016	2004-08-24	2006-01-12	REL	none
1ZT4	SPINE	the crystal structure of human cd1d with and without alpha-galactosylceramide	CD1d_cell_surface_antigen	2005-05-26	2005-07-19	REL	none
1Y3J	SPINE	solution structure of the copper(i) form of the fifth domain of menkes protein	CIRMMP26	2004-11-25	2005-03-08	REL	1Y3K
1R20	SPINE	crystal structure of the ligand-binding domains of the heterodimer ecr/usp bound to the synthetic agonist byi06830	IGBMC-0090-000 NON-SPINE:IGBMC-0091-000	2003-09-25	2003-11-18	REL	none
1RK9	SPINE	solution structure of human alpha-parvalbumin (minimized average structure)	CIRMMP07	2003-11-21	2004-06-08	REL	none
1Q7X	SPINE	solution structure of the alternatively spliced pdz2 domain (pdz2b) of ptp-bas (hptp1e)	2	2003-08-20	2003-12-02	REL	none
1X7L	SPINE	solution structure of apo-dr1885 from deinococcus radiodurans	CIRMMP12	2004-08-16	2004-08-31	Replaced by:2JQA	none
1W66	XMTB	title withheld	rv2217 TB:Rv2217	2004-08-13	2005-12-08	REL	none
2BZR	XMTB	crystal structure of accd5 (rv3280), an acyl-coa carboxylase beta- subunit from mycobacterium tuberculosis	rv3280	2005-08-22	2007-01-02	REL	none
1YSR	XMTB	crystal structure of atp binding domain of prrb from mycobacterium tuberculosis	rv0902c TB:Rv0902c	2005-02-09	2005-07-12	REL	none
1YS7	XMTB	crystal structure of the response regulator protein prra comlexed with mg2+	rv0903c TB:Rv0903c	2005-02-07	2006-02-07	REL	none
1ZEL	XMTB	crystal structure of rv2827c protein from mycobacterium tuberculosis	rv2827c TB:Rv2827c	2005-04-19	2006-05-02	REL	none
1YL5	XMTB	crystal structure of mycobacterium tuberculosis dihydrodipicolinate reductase (rv2773c) (crystal form a)	rv2773c TB:Rv2773c	2005-01-19	2006-01-17	REL	none
1S8N	XMTB	crystal structure of rv1626 from mycobacterium tuberculosis	rv1626 TB:Rv1626	2004-02-03	2004-09-21	REL	1SD5
1SD5	XMTB	crystal structure of rv1626	rv1626 TB:Rv1626	2004-02-13	2004-09-21	REL	none
1YS6	XMTB	crystal structure of the response regulatory protein prra from mycobacterium tuberculosis	rv0903c TB:Rv0903c	2005-02-07	2006-02-07	REL	1YS7
1YL6	XMTB	crystal structure of mycobacterium tuberculosis dihydrodipicolinate reductase (rv2773c) (crystal form b)	rv2773c TB:Rv2773c	2005-01-19	2006-01-17	REL	none
1W0D	XMTB	the high resolution structure of mycobacterium tuberculosis leub (rv2995c)	rv2995c TB:Rv2995c	2004-06-03	2004-12-14	REL	none
1YS3	XMTB	crystal structure of the atp binding domain of prrb from mycobacterium tuberculosis	rv0902c TB:Rv0902c	2005-02-07	2005-07-12	REL	1YSR
1YL7	XMTB	the crystal structure of mycobacterium tuberculosis dihydrodipicolinate reductase (rv2773c) in complex with nadh (crystal form c)	rv2773c TB:Rv2773c	2005-01-19	2006-01-17	REL	none
2BJB	XMTB	mycobacterium tuberculosis epsp synthase in unliganded state	rv3227 TB:Rv3227	2005-02-01	2006-03-09	REL	none
1XXX	XMTB	crystal structure of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis	rv2753c TB:Rv2753c	2004-11-09	2006-02-14	REL	none
2BT5	XMTB	structure of rv2140, a phosphatidyl-ethanolamine binding protein from mycobacterium tuberuculosis	rv2140c	2005-05-26	0000-00-00	WDRN	none
2CBK	XMTB	x-ray crystal structure of rv2018 from mycobacterium tuberculosis	rv2018	2006-01-05	0000-00-00	WDRN	none
1ZKV	XMTB	the structure of the regx3 response regulator from mycobacterium tuberculosis	rv0491	2005-05-04	0000-00-00	WDRN	none

Note 1:  Last updated: Mar 11 2010

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Sequence Redundancy Statistics

Table 5: Sequence Redundancy Statistics for Structural Genomics Centers in Europe by Experimental Status

Sequence Identity(%)	Novel Targets Status: Selected	Novel Targets Status: Cloned	Novel Targets Status: Expressed	Novel Targets Status: Purified	Novel Targets Status: Crystallized	Novel Targets Status: Crystal Structure	Novel Targets Status: NMR Structure	Novel Targets Status: in PDB
<100	6697	4558	2559	1441	362	144	28	205
<90	6568	4486	2526	1429	358	143	25	201
<70	6224	4302	2447	1391	342	135	25	194
<50	5356	3797	2271	1283	337	132	24	185
<30	3348	2555	1681	1011	298	123	23	168

Last updated: 10-03-08

Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in TargetDB which are in the same experimental status category and at least 20 amino acids long

Table 6: Sequence Redundancy Statistics for Structures Released by Structural Genomics Centers in Europe by Year

Year	Released Structures	Number of Released Structures <30% Identity at Time of Release	Percent(%) of Released Structures <30% Identity(%) at Time of Release
<= 2000	14	0	0
2001	1	0	0
2002	9	0	0
2003	26	8	31
2004	31	9	29
2005	28	7	25
2006	18	2	11
2007	3	0	0
Total	130	26	20

Last updated:10-03-11

Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in the PDB which are at least 20 amino acids long

Figure 4:   Comparison of Novel Structures with Number of Structures Released by Structural Genomics Centers in Europe by Year

Note 1:  Last updated:  10-03-11

Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in the PDB which are at least 20 amino acids long

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