PSI TargetDB

Statistics Summary Report for ISPC Center

Last updated: Mar 11 2010



Target Status Statistics

Total number of targets deposited by ISPC to TargetDB: 136

      View ISPC Target List

Table 1: Status Statistics for ISPC

Status Total Number of Targets(%) Relative to "Cloned" Targets(%) Relative to "Expressed" Targets(%) Relative to "Purified" Targets(%) Relative to "Crystallized" Targets
Cloned132100.0---
Expressed10781.1100.0--
Soluble8967.483.2--
Purified8262.176.6100.0-
Crystallized4634.843.056.1100.0
Diffraction-quality Crystals3425.831.841.573.9
Diffraction00.00.00.00.0
NMR Assigned00.00.00.0-
HSQC00.00.00.0-
Crystal Structure2619.724.331.756.5
NMR Structure00.00.00.0-
In PDB11410.613.117.130
Work Stopped16----
Test Target0----
Other0----

Last updated: Mar 11 2010

Table 2: Status Statistics for ISPC by Organism

These statistics are derived from mapping of target sequences to GenBank using >=98% sequence identity cut off

Organism Total Number1 Work Stopped Cloned Expressed Purified Crystallized Crystal Structure NMR Structure In PDB2
Viruses605310000
Bacteria7010705439251205
Prokaryota7010705439251205
Arabidopsis101110000
Drosophila403311000
Mouse1521512102101
Human3153023196503
Eukaryota605574942201409

Last updated: Mar 11 2010

Note 1:   Total counts in this table may differ from total number of targets and structures. A target is counted in different organism specifications if:
- a target is mapped to different organisms
- a targtet is a hybrid complex (for example:a complex of human and mouse polypeptides)

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Deposited Structure Statistics for ISPC Center

Number of Released X-Ray Structures: 13

Number of Released NMR Structures: 0

Total number of released structures from ISPC center in the PDB: 13

Table 3: PDB Status Statistics for Structures from ISPC

PDB StatusNumber of Structures
Total Deposited13
Released13
Release on Publication0
Release on Certain Date0
In Process0
Last updated: Mar 11 2010
Note 1:   "Total Deposited" are all structures in the PDB including structures released to the public and structures that are in the process to be released("Released on Publication" , "Released on Certain Date", etc.).

Table 4: List of Structures Deposited in the PDB by ISPC

Total number of structures: 14

Structures of distinct targets: 141

1   A target may reference several PDB IDs (example: structure of the same polypeptides with different ligands).
In this case only one structure is counted to compute number of structures of distinct targets

Related PDB_ID(s): PDB_ID(s) associated with the same target in targetDB

PDB_ID TitleTarget_id Deposition DateReleased Date PDB StatusRelated PDB_ID in TargetDB
2NVB contribution of pro275 to the thermostability of the alcohol dehydrogenases (adhs)W002082006-11-122007-11-13RELnone
1ZGB crystal structure of torpedo californica acetylcholinesterase in complex with an (r)-tacrine(10)-hupyridone inhibitor.W005682005-04-212005-08-16RELnone
1ZGC crystal structure of torpedo californica acetylcholinesterase in complex with an (rs)-tacrine(10)-hupyridone inhibitor.W005672005-04-212005-08-16RELnone
1V04 serum paraoxonase by directed evolutionW000662004-03-222004-04-23RELnone
2F1O crystal structure of nqo1 with dicoumarolW000272005-11-152006-05-16RELnone
1OGS human acid-beta-glucosidaseW001862003-05-132003-07-03RELnone
1Y7V x-ray structure of human acid-beta-glucosidase covalently bound to conduritol b epoxideW005722004-12-102005-04-12RELnone
2B5R 1b lactamase / b lactamase inhibitorW003642005-09-292006-04-11RELnone
1S0W 1b lactamse/ b lactamase inhibitorW001872004-01-052004-02-10RELnone
2B83 a single amino acid substitution in the clostridium beijerinckii alcohol dehydrogenase is critical for thermostabilizationW002832005-10-062006-09-19RELnone
1Y7W crystal structure of a halotolerant carbonic anhydrase from dunaliella salinaW005652004-12-102005-05-03RELnone
1U65 ache w. cpt-11W005662004-07-292005-07-19RELnone
1XXM the modular architecture of protein-protein binding siteW001782004-11-072005-01-18RELnone
2OET crystal structure of antizyme inhibitorW000072007-01-010000-00-00WDRNnone

Note 1:  Last updated: Mar 11 2010

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Sequence Redundancy Statistics

Table 5: Sequence Redundancy Statistics for ISPC by Experimental Status

Sequence Identity(%)Novel Targets
Status:
Selected
Novel Targets
Status:
Cloned
Novel Targets
Status:
Expressed
Novel Targets
Status:
Purified
Novel Targets
Status:
Crystallized
Novel Targets
Status:
Crystal Structure
Novel Targets
Status:
in PDB
<1001101068459311710
<90104100785528169
<709793725023118
<509390694722118
<307777674722118
Last updated: 10-03-08
Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in TargetDB which are in the same experimental status category and at least 20 amino acids long

Table 6:Sequence Redundancy Statistics for Structures Released by ISPC by Year

Year Released Structures Number of Released Structures <30% Identity at Time of Release Percent(%) of Released Structures <30% Identity(%) at Time of Release
200311100
20042150
2005600
2006300
2007100
Total13215
Last updated:10-03-11
Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in the PDB which are at least 20 amino acids long
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