PSI TargetDB

Statistics Summary Report for Non-PSI Structural Genomics Centers in North America

Last updated: Jul 2 2009


|BSGI| |S2F| |SSGCID| |CSGID| |SGX|

Target Status Statistics

Total number of targets deposited by Non-PSI Structural Genomics Centers in North America to TargetDB: 7857

Table 1: Status Statistics for Non-PSI Structural Genomics Centers in North America

Status Total Number of Targets(%) Relative to "Cloned" Targets(%) Relative to "Expressed" Targets(%) Relative to "Purified" Targets(%) Relative to "Crystallized" Targets
Cloned5687100.0---
Expressed316855.7100.0--
Soluble119921.137.8--
Purified170029.953.7100.0-
Crystallized4858.515.328.5100.0
Diffraction-quality Crystals1873.35.911.038.6
Diffraction2354.17.413.848.5
NMR Assigned10.00.00.1-
HSQC380.71.22.2-
Crystal Structure1332.34.27.827.4
NMR Structure120.20.40.7-
In PDB12434.37.714.348
Work Stopped301----
Test Target0----
Other0----

Last updated: Jul 2 2009
Note 1:   Number of targets with status "in PDB" may not be equal to number of structures determined by a project. A target may reference several PDB IDs (example: structure of the same polypeptides with different ligands). Multiple targets in TargetDB may identify the same PDB structure when a stucture is a result of collaboration between different centers and each center includes the target on its target list.

Figure 1: Target Experimental Status for Non-PSI Structural Genomics Centers in North America

Last updated: Jul 2 2009

This graph is normalized relative to number of cloned targets in TargetDB.
Targets that progressed to status "Cloned" constitute 72% of TargetDB.

Table 2: Status Statistics for Non-PSI Structural Genomics Centers in North America by Organism

Organism Total Number1 Work Stopped Cloned Expressed Purified Crystallized Crystal Structure NMR Structure In PDB2
Total Viruses15316230132001
Archaea20105541101
Bacteria610929051272792152544112612234
Total Prokaryotes612930051322797152944212712235
Yeast200000000
Plasmodium101111101
Trypanosoma101100000
Leishmania302000000
Mouse707774001
Human1109855001
Other Eukaryotes804047231413530501
Total Eukaryotes829049233114840604
Total711130156863158169048413312240

Last updated: Jul 2 2009

Note 1:   Total counts in this table may differ from total number of targets. If targtet is a hybrid complex
(for example:a complex of human and mouse polypeptides) it is counted in different organism classifications.

Note 2:   Number of targets with status "in PDB". A target may reference several PDB IDs (example: structure of the same polypeptides with different ligands).
Multiple targets in TargetDB may identify the same PDB structure when a stucture is a result of collaboration between different centers and each center includes
the target on its target list.

Figure 2: Source Organisms in Non-PSI Structural Genomics Centers in North America

Last updated: Jul 2 2009 back to top


Deposited Structure Statistics for Non-PSI Structural Genomics Centers in North America

Number of Released X-Ray Structures: 224

Number of Released NMR Structures: 19

Total number of released structures from Non-PSI Structural Genomics Centers in North America in the PDB: 243

Table 3: PDB Status Statistics for Structures from Non-PSI Structural Genomics Centers in North America

PDB StatusBSGIS2FSSGCIDCSGIDSGXTotal
Total Deposited565165802254
Released545162760243
Release on Publication102003
Release on Certain Date000000
In Process101428
Last updated: Jul 2 2009
Note 1:   "Total Deposited" are all structures in the PDB including structures released to the public and structures that are in the process to be released("Released on Publication" , "Released on Certain Date", etc.).
Note 2:  Some PDB IDs are cross referenced by different centers. Therefore difference between "Total" number of structures and direct sum of number of structures from individual centers can be observed

Figure 3: Structures Released by Non-PSI Structural Genomics Centers in North America by Year

Last updated: Jul 2 2009

Table 4: List of Structures Deposited in the PDB by Non-PSI Structural Genomics Centers in North America

Total number of structures: 255

Structures of distinct targets: 2421

1   A target may reference several PDB IDs (example: structure of the same polypeptides with different ligands).
In this case only one structure is counted to compute number of structures of distinct targets

Related PDB_ID(s): PDB_ID(s) associated with the same target in targetDB

PDB_ID CenterTitleTarget_id Deposition DateReleased Date PDB StatusRelated PDB_ID in TargetDB
3EPS BSGIthe crystal structure of isocitrate dehydrogenase kinase/phosphatase from e. coliACEK_ECO572008-09-290000-00-00AUTHnone
3G05 BSGIcrystal structure of n-terminal domain (2-550) of e.coli mnmgMNMG_ECO572009-01-270000-00-00HPUBnone
1SBZ BSGIcrystal structure of dodecameric fmn-dependent ubix-like decarboxylase from escherichia coli o157:h7PAD1_ECO572004-02-112004-10-26RELnone
2AMJ BSGIcrystal structure of modulator of drug activity b from escherichia coli o157:h7MDAB_ECO572005-08-092006-07-18RELnone
1LKZ BSGIcrystal structure of d-ribose-5-phosphate isomerase (rpia) from escherichia coli.RPIA_ECOLI2002-04-262002-05-08RELnone
1NT4 BSGIcrystal structure of escherichia coli periplasmic glucose-1-phosphatase h18a mutant complexed with glucose-1-phosphateAGP_ECOLI2003-01-282004-01-13RELnone
2FLO BSGIcrystal structure of exopolyphosphatase (ppx) from e. coli o157:h7PPX_ECO572006-01-062006-06-06RELnone
2FSU BSGIcrystal structure of the phnh protein from escherichia coliPHNH_ECOLI2006-01-232007-03-27RELnone
1FC4 BSGI2-amino-3-ketobutyrate coa ligaseKBL_ECOLI2000-07-172001-05-02RELnone
2D40 BSGIcrystal structure of z3393 from escherichia coli o157:h7Z3393_ECO572005-10-052006-09-26RELnone
1TQ5 BSGIcrystal structure of yhhw from escherichia coliYHHW_ECOLI2004-06-162005-06-14RELnone
3B8N BSGIstructure of fepe- bacterial polysaccharide co-polymeraseFEPE_ECO572007-11-012008-01-22RELnone
1Y00 BSGIsolution structure of the carbon storage regulator protein csraCSRA_ECOLI2004-11-132005-06-21RELnone
2B59 BSGIthe type ii cohesin dockerin complexCIPA_CLOTM NON-BSGI:P71143_CLOTM2005-09-272005-10-11RELnone
1GZ0 BSGI23s ribosomal rna g2251 2'o-methyltransferase rlmbRLMB_ECOLI2002-05-032002-10-17RELnone
3B8O BSGIstructure of wzze- bacterial polysaccharide co-polymeraseWZZE_ECO572007-11-012008-01-22RELnone
2FT0 BSGIcrystal structure of tdp-fucosamine acetyltransferase (wecd)- complex with acetyl-coaWECD_ECOL62006-01-232006-08-01RELnone
1XK7 BSGIcrystal structure- c2 form- of escherichia coli crotonobetainyl-coa: carnitine coa transferase (caib)CAIB_ECOLI2004-09-272005-03-15RELnone
1ZPS BSGIcrystal structure of methanobacterium thermoautotrophicum phosphoribosyl-amp cyclohydrolase hisiHIS3_METTH2005-05-172005-08-30RELnone
1K75 BSGIthe l-histidinol dehydrogenase (hisd) structure implicates domain swapping and gene duplication.HISX_ECOLI2001-10-182002-02-27RELnone
1RRZ BSGIsolution structure of glgs protein from e. coliGLGS_ECOLI2003-12-092004-06-01RELnone
2OVI BSGIstructure of the heme binding protein chuxCHUX_ECO572007-02-132008-02-12RELnone
1KON BSGIcrystal structure of e.coli yebcYEBC_ECOLI2001-12-212002-07-17RELnone
1FC5 BSGIcrystal structure of molybdopterin biosynthesis moea proteinMOEA_ECOLI2000-07-172001-07-25RELnone
1R6Y BSGIcrystal structure of ygin from escherichia coliYGIN_ECOLI2003-10-172004-11-02RELnone
1U9T BSGIcrystal structure analysis of chus, an e. coli heme oxygenaseCHUS_ECO572004-08-102005-10-25RELnone
3G2Q BSGIcrystal structure of the glycopeptide n-methyltransferase mtfa complexed with sinefunginMTFA_AMYOR2009-01-312009-05-05RELnone
1U5W BSGIcrystal structure of hypothetical protein yjjx from escherichia coliYJJX_ECOLI2004-07-282005-08-23RELnone
2OZN BSGIthe cohesin-dockerin complex of nagj and nagh from clostridium perfringensCohesin NON-BSGI:FivarDoc2007-02-262008-05-06RELnone
1ZYL BSGIcrystal structure of hypothetical protein yihe from escherichia coliRDOA_ECOLI2005-06-102006-09-19RELnone
2R1A BSGIcrystal structure of the periplasmic lipopolysaccharide transport protein lpta (yhbn), trigonal formYHBN_ECOLI2007-08-222008-04-29RELnone
1PTM BSGIcrystal structure of e.coli pdxaPDXA_ECOLI2003-06-232003-11-04RELnone
1N3B BSGIcrystal structure of dephosphocoenzyme a kinase from escherichia coliCOAE_ECOLI2002-10-252003-01-28RELnone
1FG7 BSGIcrystal structure of l-histidinol phosphate aminotransferase with pyridoxal-5'-phosphateHIS8_ECOLI2000-07-282001-08-22RELnone
2H7A BSGInmr structure of the conserved protein ycgl from escherichia coli representing the duf709 family reveals a novel a/b/a sandwich foldYCGL_ECOL62006-06-012007-04-17RELnone
1TVM BSGInmr structure of enzyme gatb of the galactitol-specific phosphoenolpyruvate-dependent phosphotransferase systemPTKB_ECO572004-06-292005-09-06RELnone
1MC3 BSGIcrystal structure of rffhRMLA2_ECOLI2002-08-052002-11-20RELnone
1SG7 BSGInmr solution structure of the putative cation transport regulator chabCHAB_ECO572004-02-232005-03-08RELnone
1O9B BSGIquinate/shikimate dehydrogenase ydib complexed with nadhYDIB_ECOLI2002-12-122003-02-01RELnone
3BE6 BSGIcrystal structure of fite (crystal form 2), a group iii periplasmic siderophore binding proteinFITE_ECO572007-11-162008-10-28RELnone
3B8P BSGIfragment of wzzb, polysaccharide co-polymerase from salmonella typhimuriumWZZB_SALTY NON-BSGI:WZZB_ECO572007-11-012008-01-22RELnone
1YQC BSGIcrystal structure of ureidoglycolate hydrolase (alla) from escherichia coli o157:h7ALLA_ECO572005-02-012005-10-18RELnone
1Q18 BSGIcrystal structure of e.coli glucokinase (glk)GLK_ECO572003-07-182004-07-27RELnone
1L1P BSGIsolution structure of the ppiase domain from e. coli trigger factorTIG_ECOLI2002-02-192003-06-24RELnone
1KK9 BSGIcrystal structure of e. coli ycioYCIO_ECOLI2001-12-062002-12-11RELnone
3CQJ BSGIcrystal structure of l-xylulose-5-phosphate 3-epimerase ulae (form b) complex with zn2+ULAE_ECO572008-04-032008-11-25RELnone
1XZO BSGIidentification of a disulfide switch in bssco, a member of the sco family of cytochrome c oxidase assembly proteinsYPMQ_BACSU2004-11-122005-03-01RELnone
1YNI BSGIcrystal structure of n-succinylarginine dihydrolase, astb, bound to substrate and product, an enzyme from the arginine catabolic pathway of escherichia coliASTB_ECOLI2005-01-242005-02-15RELnone
1KSL BSGIstructure of rsuaRSUA_ECOLI2002-01-132002-04-24RELnone
1PRZ BSGIcrystal structure of pseudouridine synthase rlud catalytic moduleRLUD_ECO572003-06-202003-11-04RELnone
2FPU BSGIcrystal structure of the n-terminal domain of e.coli hisb- complex with histidinolHIS7_ECO572006-01-172006-09-05RELnone
2AHW BSGIcrystal structure of acyl-coa transferase from e. coli o157:h7 (ydif)-thioester complex with coa- 2YDIF_ECO572005-07-282005-11-01RELnone
1P9K BSGIthe solution structure of ybcj from e. coli reveals a recently discovered alfal motif involved in rna-bindingYBCJ_ECOLI2003-02-202003-03-11RELnone
1SG5 BSGIsolution structure of yaeo, a rho-specific inhibitor of transcription terminationROF_ECOLI2004-02-232005-07-12RELnone
1P9N BSGIcrystal structure of escherichia coli mobb.MOBB_ECOLI2003-05-122003-05-20RELnone
2I6R BSGIcrystal structure of e. coli hype, a hydrogenase maturation proteinHYPE_ECO572006-08-292007-10-23RELnone
2F79 BSGIsolution structure of napd a pathway specific chaperone in napa maturationNAPD_ECOLI2005-11-300000-00-00WDRNnone
3I1I CSGID-IDP01610---none
3H88 CSGIDcrystal structure of 4'-phosphopantetheinyl transferase acps from vibrio cholerae o1 biovar eltorIDP014612009-04-290000-00-00AUTHnone
3HZN CSGIDstructure of the salmonella typhimurium nfnb dihydropteridine reductaseIDP009232009-06-230000-00-00AUTHnone
3I12 CSGIDthe crystal structure of the d-alanyl-alanine synthetase a from salmonella enterica subsp. enterica serovar typhimurium str. lt2IDP009192009-06-250000-00-00PROCnone
3ERP CSGIDstructure of idp01002, a putative oxidoreductase from and essential gene of salmonella typhimuriumIDP010022008-10-022008-11-04RELnone
3GVD CSGIDcrystal structure of serine acetyltransferase cyse from yersinia pestisIDP005382009-03-302009-05-12RELnone
3FPK CSGIDcrystal structure of ferredoxin-nadp reductase from salmonella typhimuriumIDP010742009-01-052009-02-03RELnone
3H02 CSGID2.15 angstrom resolution crystal structure of naphthoate synthase from salmonella typhimurium.IDP009952009-04-082009-04-21RELnone
3H2Y CSGIDcrystal structure of yqeh gtpase from bacillus anthracis with dgdp boundIDP902222009-04-152009-06-16RELnone
3FG0 CSGID1.85 angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betb) from staphylococcus aureus (idp00699) in complex with nad+IDP006992008-12-042008-12-30RELnone
3ED6 CSGID1.7 angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betb) from staphylococcus aureusIDP006992008-09-022008-09-23REL3FG0
3HYQ CSGIDcrystal structure of isopentenyl-diphosphate delta-isomerase from salmonella entericaseIDP019702009-06-222009-06-30RELnone
3G1Z CSGIDstructure of idp01693/yjea, a potential t-rna synthetase from salmonella typhimuriumIDP016932009-01-302009-03-10RELnone
3EDN CSGIDcrystal structure of the bacillus anthracis phenazine biosynthesis protein, phzf familyIDP000512008-09-032008-10-07RELnone
3CWC CSGIDcrystal structure of putative glycerate kinase 2 from salmonella typhimurium lt2IDP001222008-04-212008-07-08RELnone
3HMQ CSGID1.9 angstrom resolution crystal structure of a nad synthetase (nade) from salmonella typhimurium lt2 in complex with nad(+)IDP009602009-05-292009-06-16RELnone
3FZY CSGIDcrystal structure of pre-cleavage form of cysteine protease domain from vibrio cholerae rtxa toxinIDP001672009-01-262009-02-17RELnone
3EEV CSGIDcrystal structure of chloramphenicol acetyltransferase vca0300 from vibrio cholerae o1 biovar eltorIDP013502008-09-052008-09-16RELnone
3GSE CSGIDcrystal structure of menaquinone-specific isochorismate synthase from yersinia pestis co92IDP005822009-03-262009-05-05RELnone
3F09 CSGID1.82 angstrom resolution crystal structure of holo-(acyl-carrier-protein) synthase (acps) from staphylococcus aureusIDP008162008-10-242008-11-11RELnone
3HL3 CSGID2.76 angstrom crystal structure of a putative glucose-1-phosphate thymidylyltransferase from bacillus anthracis in complex with a sucrose.IDP012542009-05-262009-06-09RELnone
3E9A CSGIDcrystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from vibrio cholerae o1 biovar eltor str. n16961IDP013372008-08-212008-09-16RELnone
3FF1 CSGIDstructure of glucose 6-phosphate isomerase from staphylococcus aureusIDP007362008-12-012009-02-03RELnone
3FPI CSGIDcrystal structure of 2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthase ispf complexed with cytidine triphosphateIDP005202009-01-052009-02-03RELnone
3HJB CSGID1.5 angstrom crystal structure of glucose-6-phosphate isomerase from vibrio cholerae.IDP013292009-05-212009-06-16RELnone
3FWX CSGIDthe crystal structure of the peptide deformylase from vibrio cholerae o1 biovar el tor str. n16961IDP013572009-01-192009-03-17RELnone
3EME CSGIDcrystal structure of rhodanese-like domain protein from staphylococcus aureusIDP006402008-09-242008-10-07RELnone
3EER CSGIDhigh resolution structure of putative organic hydroperoxide resistance protein from vibrio cholerae o1 biovar eltor str. n16961IDP013252008-09-052008-10-21RELnone
3H07 CSGIDcrystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase from yersinia pestis co92IDP004792009-04-082009-05-05RELnone
3G0M CSGIDcrystal structure of cysteine desulfuration protein sufe from salmonella typhimurium lt2IDP008752009-01-282009-02-17RELnone
3GJZ CSGIDcrystal structure of microcin immunity protein mccf from bacillus anthracis str. amesIDP000382009-03-092009-04-14RELnone
3HFR CSGIDcrystal structure of glutamate racemase from listeria monocytogenesIDP003472009-05-122009-06-09RELnone
3F0I CSGIDarsenate reductase from vibrio cholerae.IDP013002008-10-242008-11-11RELnone
3FWW CSGIDthe crystal structure of the bifunctional n-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase from yersinia pestis co92IDP004272009-01-192009-03-24RELnone
3HJJ CSGIDcrystal structure of maltose o-acetyltransferase from bacillus anthracisIDP024532009-05-212009-06-02RELnone
3G25 CSGID1.9 angstrom crystal structure of glycerol kinase (glpk) from staphylococcus aureus in complex with glycerol.IDP007432009-01-302009-02-17REL3GE1
3DZC CSGID2.35 angstrom resolution structure of wecb (vc0917), a udp-n-acetylglucosamine 2-epimerase from vibrio cholerae.IDP001522008-07-292008-08-12RELnone
3DR6 CSGIDstructure of ynca, a putative acteyltransferase from salmonella typhimuriumIDP000862008-07-102008-09-09REL3DR8
3EG7 CSGIDspermidine n1-acetyltransferase from vibrio choleraeIDP016162008-09-102008-09-30RELnone
3HJV CSGID1.7 angstrom resolution crystal structure of an acyl carrier protein s-malonyltransferase from vibrio cholerae o1 biovar eltor str. n16961IDP014402009-05-222009-06-09RELnone
3DR3 CSGIDstructure of idp00107, a potential n-acetyl-gamma-glutamylphosphate reductase from shigella flexneriIDP001072008-07-102008-08-05RELnone
3GE1 CSGID2.7 angstrom crystal structure of glycerol kinase (glpk) from staphylococcus aureus in complex with adp and glycerolIDP007432009-02-242009-03-24RELnone
3H0P CSGID2.0 angstrom crystal structure of an acyl carrier protein s-malonyltransferase from salmonella typhimurium.IDP009562009-04-102009-04-21RELnone
3EC6 CSGIDcrystal structure of the general stress protein 26 from bacillus anthracis str. sterneIDP015402008-08-292008-09-16RELnone
3GO9 CSGIDpredicted insulinase family protease from yersinia pestisIDP005732009-03-182009-04-07RELnone
3F4N CSGIDcrystal structure of pyridoxal phosphate biosynthetic protein pdxj from yersinia pestisIDP004392008-11-012008-11-25RELnone
3H1S CSGIDcrystal structure of superoxide dismutase from francisella tularensis subsp. tularensis schu s4IDP018082009-04-132009-05-05RELnone
3EFE CSGIDthe crystal structure of the thij/pfpi family protein from bacillus anthracisIDP017122008-09-082008-09-23RELnone
3GEU CSGIDcrystal structure of icar from staphylococcus aureus, a member of the tetracycline repressor protein familyIDP008512009-02-262009-03-10RELnone
3HID CSGIDcrystal structure of adenylosuccinate synthetase from yersinia pestis co92IDP004222009-05-192009-06-02RELnone
3GA7 CSGID1.55 angstrom crystal structure of an acetyl esterase from salmonella typhimuriumIDP008962009-02-162009-02-24RELnone
3F6M CSGIDcrystal structure of 2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthase ispf from yersinia pestisIDP005202008-11-062008-11-25REL3FPI
3FOB CSGIDcrystal structure of bromoperoxidase from bacillus anthracisIDP000462008-12-292009-01-06RELnone
3G0S CSGIDdihydrodipicolinate synthase from salmonella typhimurium lt2IDP010042009-01-282009-02-10RELnone
3ECT CSGIDcrystal structure of the hexapeptide-repeat containing-acetyltransferase vca0836 from vibrio choleraeIDP015152008-09-022008-09-16RELnone
3G48 CSGIDcrystal structure of chaperone csaa form bacillus anthracis str. amesIDP011122009-02-032009-03-03RELnone
3GOA CSGIDcrystal structure of the salmonella typhimurium fada 3-ketoacyl-coa thiolaseIDP010712009-03-182009-03-31RELnone
3GOS CSGIDthe crystal structure of 2,3,4,5-tetrahydropyridine-2-carboxylate n-succinyltransferase from yersinia pestis co92IDP005712009-03-192009-05-12RELnone
3HHO CSGIDchaperone hscb from vibrio choleraeIDP013042009-05-152009-05-26RELnone
3DR8 CSGIDstructure of ynca, a putative acteyltransferase from salmonella typhimurium with its cofactor acetyl-coaIDP000862008-07-102008-08-12RELnone
3EGJ CSGIDn-acetylglucosamine-6-phosphate deacetylase from vibrio cholerae.IDP013342008-09-102008-09-23RELnone
3HVU CSGID1.95 angstrom crystal structure of complex of hypoxantine-guanine phosphoribosyltransferase from bacillus anthracis with 2-(n-morpholino)ethanesulfonic acid (mes)IDP018922009-06-162009-06-23RELnone
3FTT CSGIDcrystal structure of the galactoside o-acetyltransferase from staphylococcus aureusIDP006982009-01-132009-03-03RELnone
3H5Q CSGIDcrystal structure of a putative pyrimidine-nucleoside phosphorylase from staphylococcus aureusIDP006922009-04-222009-05-26RELnone
3GSD CSGID2.05 angstrom structure of a divalent-cation tolerance protein (cuta) from yersinia pestisIDP004562009-03-262009-04-07RELnone
3EGP CSGIDcrystal structure analysis of dengue-1 envelope protein domain iiiIDP002722008-09-112008-11-04RELnone
3GIU CSGID1.25 angstrom crystal structure of pyrrolidone-carboxylate peptidase (pcp) from staphylococcus aureusIDP008362009-03-062009-03-17RELnone
3GBX CSGIDserine hydroxymethyltransferase from salmonella typhimuriumIDP010112009-02-202009-03-10RELnone
3H83 CSGID2.06 angstrom resolution structure of a hypoxanthine-guanine phosphoribosyltransferase (hpt-1) from bacillus anthracis str. 'ames ancestor'IDP018922009-04-282009-05-12REL3HVU
3DQQ CSGIDthe crystal structure of the putative trna synthase from salmonella typhimurium lt2IDP001212008-07-092008-07-22RELnone
3EFV CSGIDcrystal structure of a putative succinate-semialdehyde dehydrogenase from salmonella typhimurium lt2 with bound nadIDP015302008-09-102008-11-04REL3ETF
3GHZ CSGID2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthase from salmonella typhimuriumIDP010382009-03-042009-03-17RELnone
3ETF CSGIDcrystal structure of a putative succinate-semialdehyde dehydrogenase from salmonella typhimurium lt2IDP015302008-10-072008-11-04RELnone
3E4F CSGIDcrystal structure of ba2930- a putative aminoglycoside n3-acetyltransferase from bacillus anthracisIDP000442008-08-112008-08-19RELnone
3HYL CSGIDcrystal structure of transketolase from bacillus anthracisIDP024542009-06-222009-06-30RELnone
3GRI CSGIDthe crystal structure of a dihydroorotase from staphylococcus aureusIDP007952009-03-252009-05-19RELnone
3EFB CSGIDcrystal structure of probable sor operon regulator from shigella flexneriIDP015312008-09-082008-09-23RELnone
3HYK CSGID2.31 angstrom resolution crystal structure of a holo-(acyl-carrier-protein) synthase from bacillus anthracis str. ames in complex with coa (3',5'-adp)IDP011822009-06-222009-06-30RELnone
3GC2 CSGID1.85 angstrom crystal structure of o-succinylbenzoate synthase from salmonella typhimurium in complex with succinic acidIDP009942009-02-212009-03-10RELnone
3DSA CSGIDcrystal structure of d-ribose high-affinity transport system from salmonella typhimurium lt2IDP000792008-07-112008-08-12Replaced by:3E7Nnone
1M65 S2Fycdx proteinycdX2002-07-122003-04-22RELnone
1NNV S2Fthe solution structure of hi1450HI14502003-01-142004-01-27RELnone
1JJV S2Fdephospho-coa kinase in complex with atpHI08902001-07-092002-05-01RELnone
1NMP S2Fstructural genomics, ybgi protein, unknown functionybgI2003-01-102004-01-20RELnone
1JOV S2Fcrystal structure analysis of hi1317HI13172001-07-312003-06-24RELnone
1J9A S2FoligoribonucleaseHI17152001-05-242003-06-24RELnone
1NO5 S2Fstructure of hi0073 from haemophilus influenzae, the nucleotide binding domain of the hi0073/hi0074 two protein nucleotidyl transferase.HI00732003-01-152004-03-16RELnone
1IMU S2Fsolution structure of hi0257, a ribosome binding proteinHI02572001-05-112001-10-03RELnone
1NMO S2Fstructural genomics, protein ybgi, unknown functionybgI2003-01-102004-01-20REL1NMP
1JOE S2Fcrystal structure of autoinducer-2 production protein (luxs) from heamophilus influenzaeHI04912001-07-272001-08-08RELnone
1HTW S2Fcomplex of hi0065 with adp and magnesiumHI00652001-01-012002-08-07RELnone
1NRK S2Fygfz proteinygfZ2003-01-242004-03-09RELnone
1MXI S2Fstructure of yibk from haemophilus influenzae (hi0766): a methyltransferase with a cofactor bound at a site formed by a knotHI07662002-10-022003-02-25RELnone
1RW1 S2Fyffb (pa3664) proteinPA36642003-12-152004-11-02RELnone
1R8G S2Fstructure and function of ybdkybdK2003-10-242004-08-17RELnone
1IN0 S2Fyajq protein (hi1034)HI10342001-05-112003-06-10RELnone
2OUT S2Fsolution structure of hi1506, a novel two domain protein from haemophilus influenzaeHI15062007-02-122007-05-01RELnone
1JOP S2Fyhch protein (hi0227)HI02272001-07-302003-06-17RELnone
1NU0 S2Fstructure of the double mutant (l6m; f134m, semet form) of yqgf from escherichia coli, a hypothetical proteinyqgF2003-01-302004-03-02RELnone
1J8B S2Fstructure of ybab from haemophilus influenzae (hi0442), a protein of unknown functionHI04422001-05-212003-01-14RELnone
1MWW S2Fthe structure of the hypothetical protein hi1388.1 from haemophilus influenzae reveals a tautomerase/mif foldHI1388.12002-10-012003-11-18RELnone
1DBX S2Fcrystal structure of cysteinyl-trna(pro) deacylase from h. influenzae (hi1434)HI14341999-11-032000-06-14RELnone
1FL9 S2Fthe yjee proteinHI00652000-08-132002-08-07REL1HTW
1K1E S2Fstructure of the cobalt-bound form of the deoxy-d-mannose-octulosonate 8-phosphate phosphatase (yrbi) from haemophilus influenzae (hi1679)HI16792001-09-252002-02-27RELnone
1J7G S2Fstructure of yihz from haemophilus influenzae (hi0670), a d-tyr-trna(tyr) deacylaseHI06702001-05-162003-04-22RELnone
1JOG S2Fstructure of hi0074 from heamophilus influenzae reveals the fold of a substrate binding domain of a nucleotidyltransferaseHI00742001-07-292002-12-18RELnone
2AIZ S2Fsolution structure of peptidoglycan associated lipoprotein from haemophilus influenza bound to udp-n-acetylmuramoyl-l-alanyl-d-glutamyl-meso-2,6-diaminopimeloyl-d-alanyl-d-alanineHI03812005-08-012006-03-14RELnone
1X6I S2Fcrystal structure of ygfy from escherichia coliygfY2004-08-112005-02-08REL1X6J
1J85 S2Fstructure of yibk from haemophilus influenzae (hi0766), a truncated sequence homolog of trna (guanosine-2'-o-) methyltransferase (spou)HI07662001-05-202003-02-25REL1MXI
1LQA S2Ftas protein from escherichia coli in complex with nadphb28342002-05-092003-07-08RELnone
1RXX S2Fstructure of arginine deiminasePA51712003-12-182004-01-13RELnone
3CA8 S2Fcrystal structure of escherichia coli ydcf, an s-adenosyl-l-methionine utilizing enzymeydcF2008-02-192008-05-06RELnone
1OQF S2Fcrystal structure of the 2-methylisocitrate lyaseprpB2003-03-082004-04-27RELnone
1IM8 S2Fcrystal structure of yeco from haemophilus influenzae (hi0319), a methyltransferase with a bound s-adenosylhomocysteineHI03192001-05-102001-11-07RELnone
2APN S2Fhi1723 solution structureHI17232005-08-162006-10-03RELnone
1J8D S2Fstructure of the metal-free form of the deoxy-d-mannose-octulosonate 8-phosphate phosphatase (yrbi) from haemophilus influenzae (hi1679)HI16792001-05-212002-02-27REL1K1E
1MW5 S2Fstructure of hi1480 from haemophilus influenzaeHI14802002-09-272003-11-18RELnone
1JOS S2Fribosome binding factor a(rbfa)HI12882001-07-302003-06-24RELnone
1IZM S2Fstructure of ygfb from haemophilus influenzae (hi0817), a conserved hypothetical proteinHI08172002-10-092003-12-02RELnone
1JO0 S2Fstructure of hi1333, a hypothetical protein from haemophilus influenzae with structural similarity to rna-binding proteinsHI13332001-07-262002-11-20RELnone
1X6J S2Fcrystal structure of ygfy from escherichia coliygfY2004-08-112005-02-08RELnone
1MWQ S2Fstructure of hi0828, a hypothetical protein from haemophilus influenzae with a putative active-site phosphohistidineHI08282002-09-302003-11-25RELnone
1DBU S2Fcrystal structure of cysteinyl-trna(pro) deacylase protein from h. influenzae (hi1434)HI14341999-11-032000-06-14REL1DBX
1XAX S2Fnmr structure of hi0004, a putative essential gene product from haemophilus influenzaeHI00042004-08-262005-01-18RELnone
1NNX S2Fstructure of the hypothetical protein ygiw from e. coli.ygiW2003-01-142004-03-09RELnone
1NMN S2Fstructure of yqgf from escherichia coli, a hypothetical proteinyqgF2003-01-102004-03-02REL1NU0
1JN1 S2Fstructure of 2c-methyl-d-erythritol 2,4-cyclodiphosphate synthase from haemophilus influenzae (hi0671)HI06712001-07-212002-08-21RELnone
1J7H S2Fsolution structure of hi0719, a hypothetical protein from haemophilus influenzaeHI07192001-05-162003-02-11RELnone
1JAL S2Fychf protein (hi0393)HI03932001-05-302003-03-25RELnone
1NIJ S2Fyjia proteinyjiA2002-12-242003-06-24RELnone
1NNG S2Fstructure of hi0827, a thioesterase acting on short-chain acyl-coa compounds.HI08272003-01-132004-03-09Replaced by:1YLInone
ND_151 SGXExperimental status "in PDB", PDB ID is not provided2935f---none
ND_150 SGXExperimental status "in PDB", PDB ID is not provided2935c---none
3GTD SSGCID2.4 angstrom crystal structure of fumarate hydratase from rickettsia prowazekiiRiprA.00047.a2009-03-270000-00-00AUTHnone
3EZL SSGCIDcrystal structure of acetyacetyl-coa reductase from burkholderia pseudomallei 1710bBupsA.00010.e2008-10-230000-00-00HPUBnone
3HMO SSGCIDcrystal structure of human mps1 catalytic domain in complex with the inhibitor staurosporineBaheA.00734.a2009-05-290000-00-00HPUBnone
3GK0 SSGCIDcrystal structure of pyridoxal phosphate biosynthetic protein from burkholderia pseudomalleiBupsA.00131.a2009-03-092009-03-17RELnone
2KDN SSGCIDsolution structure of pfe0790c, a putative bola-like protein from the protozoan parasite plasmodium falciparum.PlfaA.01650.a2009-01-122009-01-20RELnone
3GRK SSGCIDcrystal structure of short chain dehydrogenase reductase sdr glucose-ribitol dehydrogenase from brucella melitensisBrabA.00010.a2009-03-252009-04-07RELnone
3GKA SSGCIDcrystal structure of n-ethylmaleimidine reductase from burkholderia pseudomalleiBupsA.00093.a2009-03-102009-03-17RELnone
3DMO SSGCID1.6 a crystal structure of cytidine deaminase from burkholderia pseudomalleiBupsA.00001.a2008-07-012008-07-15RELnone
3GWA SSGCID1.6 angstrom crystal structure of 3-oxoacyl-(acyl-carrier-protein) synthase iiiBupsA.00171.a2009-03-312009-04-28RELnone
3GMT SSGCIDcrystal structure of adenylate kinase from burkholderia pseudomalleiBupsA.00064.a2009-03-152009-06-02RELnone
3HGB SSGCIDcrystal structure of glycine cleavage system protein h from mycobacterium tuberculosisMytuD.01046.a2009-05-132009-05-26RELnone
3HHJ SSGCIDcrystal structure of mutator mutt from bartonella henselaeBaheA.00264.a2009-05-152009-05-26RELnone
3D6B SSGCID2.2 a crystal structure of glutaryl-coa dehydrogenase from burkholderia pseudomalleiBupsA.00027.a2008-05-192008-06-03RELnone
3D53 SSGCID2.2 a crystal structure of inorganic pyrophosphatase from rickettsia prowazekiiRiprA.00023.a2008-05-152008-05-27RELnone
3D64 SSGCIDcrystal structure of s-adenosyl-l-homocysteine hydrolase from burkholderia pseudomalleiBupsA.00032.a2008-05-182008-06-03RELnone
3E7D SSGCIDcrystal structure of precorrin-8x methyl mutase cbic/cobh from brucella melitensisBrabA.00006.a2008-08-182008-08-26RELnone
3E5B SSGCID2.4 a crystal structure of isocitrate lyase from brucella melitensisBrabA.00014.a2008-08-132008-08-26RELnone
3ENK SSGCID1.9a crystal structure of udp-glucose 4-epimerase from burkholderia pseudomalleiBupsA.00085.b2008-09-252008-10-28RELnone
3DMS SSGCID1.65a crystal structure of isocitrate dehydrogenase from burkholderia pseudomalleiBupsA.00092.a2008-07-012008-07-15RELnone
3HJA SSGCIDcrystal structure of glyceraldehyde-3-phosphate dehydrogenase from borrelia burgdorferiBobuA.00444.a2009-05-212009-06-02RELnone
3G87 SSGCIDcrystal structure of malonyl coa-acyl carrier protein transacylase from burkholderia pseudomallei using dried seaweed as nucleant or proteaseBupsA.00141.c2009-02-112009-02-24RELnone
3FVB SSGCIDcrystal structure of ferritin (bacterioferritin) from brucella melitensisBrabA.00028.a2009-01-152009-02-03RELnone
2KHR SSGCIDsolution structure of rv2377c, a mtbh-like protein from mycobacterium tuberculosisMytuD.01649.a2009-04-102009-05-05RELnone
3FQ3 SSGCIDcrystal structure of inorganic phosphatase from brucella melitensisBrabA.00023.a2009-01-062009-01-20RELnone
3DPI SSGCIDcrystal structure of nad+ synthetase from burkholderia pseudomalleiBupsA.00025.a2008-07-082008-07-29RELnone
3GE4 SSGCIDcrystal structure of ferritin:dna-binding protein dps from brucella melitensisBrabA.00136.a2009-02-252009-03-03RELnone
3GNQ SSGCIDcrystal structure of glyceraldehyde-3-phosphate dehydrogenase, type i from burkholderia pseudomalleiBupsA.00052.a2009-03-172009-03-24RELnone
3GIR SSGCIDcrystal structure of glycine cleavage system aminomethyltransferase tBaheA.00657.a2009-03-062009-03-17RELnone
3CEZ SSGCIDcrystal structure of methionine-r-sulfoxide reductase from burkholderia pseudomalleiBupsA.00033.a ATCG3D:ATCG3D_202008-02-292008-03-18RELnone
3GVG SSGCIDcrystal structure of triosephosphate isomerase from mycobacterium tuberculosisMytuD.00317.a2009-03-312009-04-14RELnone
3GBZ SSGCIDstructure of the cmgc cdk kinase from giardia lambliaGilaA.00333.a2009-02-202009-03-24RELnone
3EOO SSGCID2.9a crystal structure of methyl-isocitrate lyase from burkholderia pseudomalleiBupsA.00014.b2008-09-282008-10-21RELnone
3GK3 SSGCIDcrystal structure of acetoacetyl-coa reductase from burkholderia pseudomallei 1710bBupsA.00010.g2009-03-092009-03-24RELnone
3EMK SSGCID2.5a crystal structure of glucose/ribitol dehydrogenase from brucella melitensisBrabA.00010.b2008-09-242008-10-28RELnone
3DOC SSGCIDcrystal structure of trka glyceraldehyde-3-phosphate dehydrogenase from brucella melitensisBrabA.00052.a2008-07-032008-07-29RELnone
3EZN SSGCIDcrystal structure of phosphoglyceromutase from burkholderia pseudomallei 1710bBupsA.00114.a2008-10-232008-11-11RELnone
3H7F SSGCIDcrystal structure of serine hydroxymethyltransferase from mycobacterium tuberculosisMytuD.00783.a2009-04-242009-05-05RELnone
3GNN SSGCIDcrystal structure of nicotinate-nucleotide pyrophosphorylase from burkholderi pseudomalleiBupsA.00056.a2009-03-172009-03-31RELnone
3GVH SSGCIDcrystal structure of lactate/malate dehydrogenase from brucella melitensisBrabA.00005.a2009-03-312009-04-14RELnone
3D63 SSGCIDcrystal structure of inorganic pyrophosphatase from burkholderia pseudomalleiBupsA.00023.a2008-05-182008-07-08RELnone
3F9I SSGCIDcrystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase rickettsia prowazekiiRiprA.00010.b2008-11-132008-11-25RELnone
3DAH SSGCID2.3 a crystal structure of ribose-phosphate pyrophosphokinase from burkholderia pseudomalleiBupsA.00035.a2008-05-292008-06-10RELnone
3E5Y SSGCIDcrystal structure of trmh family rna methyltransferase from burkholderia pseudomalleiBupsA.00072.a2008-08-142008-08-26RELnone
3H81 SSGCIDcrystal structure of enoyl-coa hydratase from mycobacterium tuberculosisMytuD.00358.a2009-04-282009-05-12RELnone
3GAF SSGCID2.2a crystal structure of 7-alpha-hydroxysteroid dehydrogenase from brucella melitensisBrabA.00010.e2009-02-172009-03-17RELnone
2KE0 SSGCIDsolution structure of peptidyl-prolyl cis-trans isomerase from burkholderia pseudomalleiBupsA.00130.a2009-01-212009-03-03RELnone
3FTP SSGCIDcrystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from burkholderia pseudomallei at 2.05 a resolutionBupsA.00010.a2009-01-132009-01-27RELnone
3EG4 SSGCIDcrystal structure of 2,3,4,5-tetrahydropyridine-2-carboxylate n-succinyltransferase from brucella melitensis biovar abortus 2308BrabA.00002.a2008-09-102008-09-23RELnone
3E60 SSGCIDcrystal structure of 3-oxoacyl-(acyl carrier protein) synthase ii from bartonella henselaeBaheA.00113.b2008-08-142008-08-26RELnone
3EK1 SSGCIDcrystal structure of aldehyde dehydrogenase from brucella melitensis biovar abortus 2308BrabA.00020.a2008-09-182008-09-30RELnone
3D5T SSGCIDcrystal structure of malate dehydrogenase from burkholderia pseudomalleiBupsA.00005.a2008-05-162008-06-03RELnone
3GRP SSGCID2.1 angstrom crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from bartonella henselaeBaheA.00010.c2009-03-262009-04-07RELnone
3HE2 SSGCIDcrystal structure of enoyl-coa hydratase from mycobacterium tuberculosisMytuD.01381.a2009-05-072009-06-09RELnone
3ECD SSGCIDcrystal structure of serine hydroxymethyltransferase from burkholderia pseudomalleiBupsA.00008.a2008-08-292008-09-09RELnone
3HN6 SSGCIDcrystal structure of glucosamine-6-phosphate deaminase from borrelia burgdorferiBobuA.00564.a2009-05-292009-06-09RELnone
3FS2 SSGCIDcrystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from bruciella melitensis at 1.85a resolutionBrabA.00102.a2009-01-092009-01-20RELnone
3F0D SSGCIDhigh resolution crystal structure of 2c-methyl-d-erythritol 2,4-cyclodiphosphatase synthase from burkholderia pseudomalleiBupsA.00122.a2008-10-242008-11-04RELnone
3GWC SSGCIDcrystal structure of mycobacterium tuberculosis thymidylate synthase x bound to fdump and fadMytuD.01655.a2009-03-312009-04-28RELnone
3EK2 SSGCIDcrystal structure of eonyl-(acyl carrier protein) reductase from burkholderia pseudomallei 1719bBupsA.00010.b2008-09-182008-09-30RELnone
3EZO SSGCIDcrystal structure of acyl-carrier-protein s-malonyltransferase from burkholderia pseudomallei 1710bBupsA.00141.a2008-10-232008-11-11RELnone
3HHE SSGCIDcrystal structure of ribose-5-phosphate isomerase a from bartonella henselaeBaheA.00944.a2009-05-152009-05-26RELnone
3GVC SSGCIDcrystal structure of probable short-chain dehydrogenase-reductase from mycobacterium tuberculosisMytuD.00472.a2009-03-302009-04-07RELnone
3EZ4 SSGCIDcrystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase from burkholderia pseudomalleiBupsA.00112.a2008-10-222008-11-04RELnone
2KHP SSGCIDsolution structure of glutaredoxin from brucella melitensisBrabA.00079.a2009-04-102009-05-05RELnone
3DMP SSGCID2.6 a crystal structure of uracil phosphoribosyltransferase from burkholderia pseudomalleiBupsA.00076.a2008-07-012008-07-15RELnone

Note 1:  Last updated: Jul 2 2009

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Sequence Redundancy Statistics

Table 5: Sequence Redundancy Statistics for Non-PSI Structural Genomics Centers in North America by Experimental Status

Sequence Identity(%)Novel Targets
Status:
Selected
Novel Targets
Status:
Cloned
Novel Targets
Status:
Expressed
Novel Targets
Status:
Purified
Novel Targets
Status:
Crystallized
Novel Targets
Status:
Crystal Structure
Novel Targets
Status:
NMR Structure
Novel Targets
Status:
in PDB
<100665543762545150143611512215
<90631442142454147042611411215
<70590939832339141541311211210
<50480333982058127037910411197
<302316201113739823369811185
Last updated: 09-04-28
Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in TargetDB which are in the same experimental status category and at least 20 amino acids long

Table 6: Sequence Redundancy Statistics for Structures Released by Non-PSI Structural Genomics Centers in North America by Year

Year Released Structures Number of Released Structures <30% Identity at Time of Release Percent(%) of Released Structures <30% Identity(%) at Time of Release
<= 20002150
20016350
200215640
2003251352
2004181161
200517741
20068338
20074250
20086658
20098245
Total2435523
Last updated:09-07-02
Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in the PDB which are at least 20 amino acids long

Figure 4:   Comparison of Novel Structures with Number of Structures Released by Non-PSI Structural Genomics Centers in North America by Year

Note 1:  Last updated:  09-07-02
Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in the PDB which are at least 20 amino acids long
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