Statistics Summary Report for SGX Center

Last updated: Mar 11 2010

• Target Status Statistics
  • Table 1: Status Statistics for SGX
  • Table 2: Status Statistics for SGX by Organisms
• Deposited Structure Statistics
  • Table 3: PDB Status Statistics for Structures from SGX
  • Table 4: List of Structures Deposited by SGX in the PDB
• Sequence Redundancy Statistics
  • Table 5: Sequence Redundancy Statistics for SGX by Experimental Status
  • Table 6: Sequence Redundancy Statistics for Structures Released by SGX in the PDB by Year

Target Status Statistics

Total number of targets deposited by SGX to TargetDB: 47

      View SGX Target List

Table 1: Status Statistics for SGX

Status	Total Number of Targets	(%) Relative to "Cloned" Targets	(%) Relative to "Expressed" Targets	(%) Relative to "Purified" Targets	(%) Relative to "Crystallized" Targets
Cloned	36	100.0	-	-	-
Expressed	36	100.0	100.0	-	-
Soluble	35	97.2	97.2	-	-
Purified	19	52.8	52.8	100.0	-
Crystallized	12	33.3	33.3	63.2	100.0
Diffraction-quality Crystals	0	0.0	0.0	0.0	0.0
Diffraction	7	19.4	19.4	36.8	58.3
NMR Assigned	0	0.0	0.0	0.0	-
HSQC	0	0.0	0.0	0.0	-
Crystal Structure	0	0.0	0.0	0.0	0.0
NMR Structure	0	0.0	0.0	0.0	-
In PDB1	2	5.6	5.6	10.5	17
Work Stopped	0	-	-	-	-
Test Target	0	-	-	-	-
Other	0	-	-	-	-

Last updated: Mar 11 2010

Table 2: Status Statistics for SGX by Organism

These statistics are derived from mapping of target sequences to GenBank using >=98% sequence identity cut off

Organism	Total Number1	Work Stopped	Cloned	Expressed	Purified	Crystallized	Crystal Structure	NMR Structure	In PDB2
Yeast	5	0	1	1	0	0	0	0	0
Mouse	7	0	7	7	7	4	0	0	1
Human	11	0	9	9	5	5	0	0	1
Eukaryota	45	0	35	35	19	12	0	0	2

Last updated: Mar 11 2010

Note 1:   Total counts in this table may differ from total number of targets and structures. A target is counted in different organism specifications if:
- a target is mapped to different organisms
- a targtet is a hybrid complex (for example:a complex of human and mouse polypeptides)

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Deposited Structure Statistics for SGX Center

Number of Released X-Ray Structures: 0

Number of Released NMR Structures: 0

Total number of released structures from SGX center in the PDB: 0

Table 3: PDB Status Statistics for Structures from SGX

PDB Status	Number of Structures
Total Deposited	2
Released	0
Release on Publication	0
Release on Certain Date	0
In Process	2

Last updated: Mar 11 2010

Note 1:   "Total Deposited" are all structures in the PDB including structures released to the public and structures that are in the process to be released("Released on Publication" , "Released on Certain Date", etc.).

Table 4: List of Structures Deposited in the PDB by SGX

Total number of structures: 2

Structures of distinct targets: 21

1   A target may reference several PDB IDs (example: structure of the same polypeptides with different ligands).
In this case only one structure is counted to compute number of structures of distinct targets

Related PDB_ID(s): PDB_ID(s) associated with the same target in targetDB

PDB_ID	Title	Target_id	Deposition Date	Released Date	PDB Status	Related PDB_ID in TargetDB
ND_156	Experimental status "in PDB", PDB ID is not provided	2935f	-	-	-	none
ND_155	Experimental status "in PDB", PDB ID is not provided	2935c	-	-	-	none

Note 1:  Last updated: Mar 11 2010

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Sequence Redundancy Statistics

Table 5: Sequence Redundancy Statistics for SGX by Experimental Status

Sequence Identity(%)	Novel Targets Status: Selected	Novel Targets Status: Cloned	Novel Targets Status: Expressed	Novel Targets Status: Purified	Novel Targets Status: Crystallized	Novel Targets Status: Crystal Structure	Novel Targets Status: in PDB
<100	19	16	16	8	6	0	2
<90	7	9	9	6	5	0	2
<70	1	2	2	2	2	0	1
<50	1	1	1	1	1	0	1
<30	1	1	1	1	1	0	1

Last updated: 10-03-08

Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in TargetDB which are in the same experimental status category and at least 20 amino acids long

Table 6:Sequence Redundancy Statistics for Structures Released by SGX by Year

Year

Released Structures

Number of Released Structures <30% Identity at Time of Release

Percent(%) of Released Structures <30% Identity(%) at Time of Release

Last updated:10-03-11

Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in the PDB which are at least 20 amino acids long

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