PSI TargetDB

Statistics Summary Report for SSGCID Center

Last updated: Mar 17 2010



Target Status Statistics

Total number of targets deposited by SSGCID to TargetDB: 4107

      View SSGCID Target List

Table 1: Status Statistics for SSGCID

Status Total Number of Targets(%) Relative to "Cloned" Targets(%) Relative to "Expressed" Targets(%) Relative to "Purified" Targets(%) Relative to "Crystallized" Targets
Cloned2147100.0---
Expressed169078.7100.0--
Soluble121156.471.7--
Purified76535.645.3100.0-
Crystallized27913.016.536.5100.0
Diffraction-quality Crystals1657.79.821.659.1
Diffraction1657.79.821.659.1
NMR Assigned100.50.61.3-
HSQC200.91.22.6-
Crystal Structure1235.77.316.144.1
NMR Structure90.40.51.2-
In PDB11296.07.616.943
Work Stopped122----
Test Target0----
Other0----

Last updated: Mar 17 2010

Table 2: Status Statistics for SSGCID by Organism

These statistics are derived from mapping of target sequences to GenBank using >=98% sequence identity cut off

Organism Total Number1 Work Stopped Cloned Expressed Purified Crystallized Crystal Structure NMR Structure In PDB2
Viruses200111073202
Bacteria298285133911095212071048110
Prokaryota298285133911095212071048110
Yeast101100000
Plasmodium906310011
Trypanosoma302210000
Leishmania302220000
Mouse101100000
Human101100000
Eukaryota978366994982356717117
Uncultured or unidentified202100000

Last updated: Mar 17 2010

Note 1:   Total counts in this table may differ from total number of targets and structures. A target is counted in different organism specifications if:
- a target is mapped to different organisms
- a targtet is a hybrid complex (for example:a complex of human and mouse polypeptides)

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Deposited Structure Statistics for SSGCID Center

Number of Released X-Ray Structures: 114

Number of Released NMR Structures: 7

Total number of released structures from SSGCID center in the PDB: 121

Table 3: PDB Status Statistics for Structures from SSGCID

PDB StatusNumber of Structures
Total Deposited127
Released121
Release on Publication2
Release on Certain Date0
In Process4
Last updated: Mar 17 2010
Note 1:   "Total Deposited" are all structures in the PDB including structures released to the public and structures that are in the process to be released("Released on Publication" , "Released on Certain Date", etc.).

Table 4: List of Structures Deposited in the PDB by SSGCID

Total number of structures: 127

Structures of distinct targets: 1271

1   A target may reference several PDB IDs (example: structure of the same polypeptides with different ligands).
In this case only one structure is counted to compute number of structures of distinct targets

Related PDB_ID(s): PDB_ID(s) associated with the same target in targetDB

PDB_ID TitleTarget_id Deposition DateReleased Date PDB StatusRelated PDB_ID in TargetDB
2KVC -MytuD.17112.a---none
3LD3 crystal structure of inorganic phosphatase from anaplasma phagocytophilum at 1.75a resolutionAnphA.01382.a2010-01-120000-00-00AUTHnone
3M1X crystal structure of a putative endoribonuclease l-psp from entamoeba histolytica, rhomobohedral formEnhiA.00579.a2010-03-050000-00-00AUTHnone
3LRF crystal structure of beta-ketoacyl synthase from brucella melitensisBrabA.00113.a2010-02-110000-00-00AUTHnone
3LA9 crystal structure of trimeric autotransporter hep hag family/haemagluttinin family protein xada from burkholderia pseudomallei, iodide phasedBupsA.01663.a2010-01-060000-00-00HPUBnone
3LR0 periplasmic domain of the riss sensor protein from burkholderia pseudomallei, iodide phased at low phBupsA.00863.i2010-02-100000-00-00HPUBnone
3GK0 crystal structure of pyridoxal phosphate biosynthetic protein from burkholderia pseudomalleiBupsA.00131.a2009-03-092009-03-17RELnone
3IEF crystal structure of trna guanine-n1-methyltransferase from bartonella henselae using mpcs.BaheA.01015.a2009-07-222009-08-11RELnone
3I0P crystal structure of malate dehydrogenase from entamoeba histolyticaEnhiA.01228.a2009-06-252009-07-14RELnone
2KDN solution structure of pfe0790c, a putative bola-like protein from the protozoan parasite plasmodium falciparum.PlfaA.01650.a2009-01-122009-01-20RELnone
3INN crystal structure of pantoate-beta-alanine-ligase in complex with atp at low occupancy at 2.1 a resolutionBrabA.00097.a2009-08-122009-10-06RELnone
3GRK crystal structure of short chain dehydrogenase reductase sdr glucose-ribitol dehydrogenase from brucella melitensisBrabA.00010.a2009-03-252009-04-07RELnone
3I3F hypothetical protein from giardia lamblia gl50803_14299GilaA.00312.a2009-06-302009-09-01RELnone
3HWI crystal structure of probable thiosulfate sulfurtransferase cysa2 (rhodanese-like protein) from mycobacterium tuberculosisMytuD.01083.a2009-06-172009-06-30RELnone
3LB5 crystal structure of hit-like protein involved in cell-cycle regulation from bartonella henselae with unknown ligandBaheA.01112.a2010-01-072010-01-19RELnone
3IDO crystal structure of protein tyrosine phosphatase from entamoeba histolytica with a phosphotyrosine crude mimic hepes molecule in the active siteEnhiA.01424.b2009-07-212009-07-28RELnone
3GKA crystal structure of n-ethylmaleimidine reductase from burkholderia pseudomalleiBupsA.00093.a2009-03-102009-03-17RELnone
3DMO 1.6 a crystal structure of cytidine deaminase from burkholderia pseudomalleiBupsA.00001.a2008-07-012008-07-15RELnone
3LG6 crystal structure of putative glutathione transferase from coccidioides immitisCoimA.00410.a2010-01-192010-01-26RELnone
3GWA 1.6 angstrom crystal structure of 3-oxoacyl-(acyl-carrier-protein) synthase iiiBupsA.00171.a2009-03-312009-04-28RELnone
3LUZ crystal structure of extragenic suppressor protein suhb from bartonella henselae, via combined iodide sad molecular replacementBaheA.00759.a2010-02-182010-03-02RELnone
3GMT crystal structure of adenylate kinase from burkholderia pseudomalleiBupsA.00064.a2009-03-152009-06-02RELnone
3HGB crystal structure of glycine cleavage system protein h from mycobacterium tuberculosisMytuD.01046.a2009-05-132009-05-26RELnone
3HHJ crystal structure of mutator mutt from bartonella henselaeBaheA.00264.a2009-05-152009-05-26RELnone
3D6B 2.2 a crystal structure of glutaryl-coa dehydrogenase from burkholderia pseudomalleiBupsA.00027.a2008-05-192008-06-03RELnone
3IXC crystal structure of hexapeptide transferase family protein from anaplasma phagocytophilumAnphA.01106.a2009-09-032009-09-22RELnone
3D53 2.2 a crystal structure of inorganic pyrophosphatase from rickettsia prowazekiiRiprA.00023.a2008-05-152008-05-27RELnone
3D64 crystal structure of s-adenosyl-l-homocysteine hydrolase from burkholderia pseudomalleiBupsA.00032.a2008-05-182008-06-03RELnone
3ICO crystal structure of 6-phosphogluconolactonase from mycobacterium tuberculosisMytuD.01244.a2009-07-172009-07-28RELnone
3KC6 crystal structure of the large c-terminal domain of polymerase basic protein 2 from influenza virus a/viet nam/1203/2004 (h5n1)InvaA.07055.a2009-10-202010-03-09RELnone
3E7D crystal structure of precorrin-8x methyl mutase cbic/cobh from brucella melitensisBrabA.00006.a2008-08-182008-08-26RELnone
3E5B 2.4 a crystal structure of isocitrate lyase from brucella melitensisBrabA.00014.a2008-08-132008-08-26RELnone
3ENK 1.9a crystal structure of udp-glucose 4-epimerase from burkholderia pseudomalleiBupsA.00085.b2008-09-252008-10-28RELnone
3DMS 1.65a crystal structure of isocitrate dehydrogenase from burkholderia pseudomalleiBupsA.00092.a2008-07-012008-07-15RELnone
3JST crystal structure of transcriptional coactivator/pterin dehydratase from brucella melitensisBrabA.00012.a2009-09-102009-09-22RELnone
3HJA crystal structure of glyceraldehyde-3-phosphate dehydrogenase from borrelia burgdorferiBobuA.00444.a2009-05-212009-06-02RELnone
3K9G crystal structure of a plasmid partition protein from borrelia burgdorferi at 2.25a resolution, iodide soakBobuA.01478.a2009-10-152009-11-03RELnone
3G87 crystal structure of malonyl coa-acyl carrier protein transacylase from burkholderia pseudomallei using dried seaweed as nucleant or proteaseBupsA.00141.c2009-02-112009-02-24RELnone
3FVB crystal structure of ferritin (bacterioferritin) from brucella melitensisBrabA.00028.a2009-01-152009-02-03RELnone
2KHR solution structure of rv2377c, a mtbh-like protein from mycobacterium tuberculosisMytuD.01649.a2009-04-102009-05-05RELnone
3EZL crystal structure of acetyacetyl-coa reductase from burkholderia pseudomallei 1710bBupsA.00010.e2008-10-232009-07-07RELnone
3FQ3 crystal structure of inorganic phosphatase from brucella melitensisBrabA.00023.a2009-01-062009-01-20RELnone
3DPI crystal structure of nad+ synthetase from burkholderia pseudomalleiBupsA.00025.a2008-07-082008-07-29RELnone
3KCQ crystal structure of phosphoribosylglycinamide formyltransferase from anaplasma phagocytophilumAnphA.00677.a2009-10-212009-12-15RELnone
3GE4 crystal structure of ferritin:dna-binding protein dps from brucella melitensisBrabA.00136.a2009-02-252009-03-03RELnone
3KZU crystal structure of 3-oxoacyl-(acyl carrier protein) synthase ii from brucella melitensisBrabA.00113.b2009-12-082009-12-15RELnone
3HWK crystal structure of methylcitrate synthase from mycobacterium tuberculosisMytuD.00698.a2009-06-172009-06-30RELnone
3KW3 crystal structure of alanine racemase from bartonella henselae with covalently bound pyridoxal phosphateBaheA.00339.a2009-11-302009-12-22RELnone
3I4T crystal structure of putative diphthine synthase from entamoeba histolyticaEnhiA.01437.a2009-07-022009-07-28RELnone
3KHP crystal structure of a possible dehydrogenase from mycobacterium tuberculosis at 2.3a resolutionMytuD.00504.a2009-10-302009-12-01RELnone
3K5P crystal structure of amino acid-binding act: d-isomer specific 2-hydroxyacid dehydrogenase catalytic domain from brucella melitensisBrabA.00021.a2009-10-072009-11-03RELnone
3GNQ crystal structure of glyceraldehyde-3-phosphate dehydrogenase, type i from burkholderia pseudomalleiBupsA.00052.a2009-03-172009-03-24RELnone
3L0G crystal structure of nicotinate-nucleotide pyrophosphorylase from ehrlichia chaffeensis at 2.05a resolutionEhchA.01074.a2009-12-092009-12-22RELnone
3GIR crystal structure of glycine cleavage system aminomethyltransferase t from bartonella henselaeBaheA.00657.a2009-03-062009-03-17RELnone
3HZU crystal structure of probable thiosulfate sulfurtransferase ssea (rhodanese) from mycobacterium tuberculosisMytuD.01241.a2009-06-242009-07-07RELnone
3CEZ crystal structure of methionine-r-sulfoxide reductase from burkholderia pseudomalleiBupsA.00033.a ATCG3D:ATCG3D_202008-02-292008-03-18RELnone
3JS9 crystal structure of nucleoside diphosphate kinase family protein from babesia bovisBaboA.00819.a2009-09-092009-09-22RELnone
3KX6 crystal structure of fructose-1,6-bisphosphate aldolase from babesia bovis at 2.1a resolutionBaboA.00974.a2009-12-022009-12-22RELnone
3GVG crystal structure of triosephosphate isomerase from mycobacterium tuberculosisMytuD.00317.a2009-03-312009-04-14RELnone
3GBZ structure of the cmgc cdk kinase from giardia lambliaGilaA.00333.a2009-02-202009-03-24RELnone
3I4E crystal structure of isocitrate lyase from burkholderia pseudomalleiBupsA.00014.a2009-07-012009-07-14RELnone
3LO0 crystal structure of inorganic pyrophosphatase from ehrlichia chaffeensisEhchA.01623.a2010-02-032010-02-16RELnone
3EOO 2.9a crystal structure of methyl-isocitrate lyase from burkholderia pseudomalleiBupsA.00014.b2008-09-282008-10-21RELnone
3GK3 crystal structure of acetoacetyl-coa reductase from burkholderia pseudomallei 1710bBupsA.00010.g2009-03-092009-03-24RELnone
3IPW crystal structure of hydrolase tatd family protein from entamoeba histolyticaEnhiA.00292.a2009-08-182009-09-01RELnone
3EMK 2.5a crystal structure of glucose/ribitol dehydrogenase from brucella melitensisBrabA.00010.b2008-09-242008-10-28RELnone
3LLS crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from mycobacterium tuberculosisMytuD.00010.a2010-01-292010-02-16RELnone
3DOC crystal structure of trka glyceraldehyde-3-phosphate dehydrogenase from brucella melitensisBrabA.00052.a2008-07-032008-07-29RELnone
3IJP crystal structure of dihydrodipicolinate reductase from bartonella henselae at 2.0a resolutionBaheA.00189.a2009-08-042009-08-11RELnone
3EZN crystal structure of phosphoglyceromutase from burkholderia pseudomallei 1710bBupsA.00114.a2008-10-232008-11-11RELnone
3LQW crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from entamoeba histolyticaEnhiA.01206.a2010-02-102010-03-09RELnone
3H7F crystal structure of serine hydroxymethyltransferase from mycobacterium tuberculosisMytuD.00783.a2009-04-242009-05-05RELnone
3IX6 crystal structure of thymidylate synthase thya from brucella melitensisBrmeA.00249.a2009-09-032009-09-22RELnone
3KRE crystal structure of phosphoribosylaminoimidazole-succinocarboxamide synthase from ehrlichia chaffeensis at 1.8a resolutionEhchA.00530.a2009-11-182009-12-01RELnone
2KLX solution structure of glutaredoxin from bartonella henselae str. houstonBaheA.00334.a2009-07-102009-07-28RELnone
3KRB structure of aldose reductase from giardia lamblia at 1.75a resolutionGilaA.01452.a2009-11-182009-12-01RELnone
3KZX crystal structure of a had-superfamily hydrolase from ehrlichia chaffeensis at 1.9a resolutionEhchA.01190.a2009-12-082009-12-22RELnone
3GNN crystal structure of nicotinate-nucleotide pyrophosphorylase from burkholderi pseudomalleiBupsA.00056.a2009-03-172009-03-31RELnone
3HM0 crystal structure of probable thioesterase from bartonella henselaeBaheA.00734.a2009-05-282009-06-09RELnone
3LGJ crystal structure of single-stranded binding protein (ssb) from bartonella henselaeBaheA.01120.b2010-01-202010-02-16RELnone
2KOK solution structure of an arsenate reductase (arsc) related protein from brucella melitensis. seattle structural genomics center for infectious disease target braba.00007.a.BrabA.00007.a2009-09-232009-10-13RELnone
3LD9 crystal structure of thymidylate kinase from ehrlichia chaffeensis at 2.15a resolutionEhchA.01616.a2010-01-122010-02-16RELnone
3GVH crystal structure of lactate/malate dehydrogenase from brucella melitensisBrabA.00005.a2009-03-312009-04-14RELnone
3K2E crystal structure of enoyl-(acyl-carrier-protein) reductase from anaplasma phagocytophilum at 1.9a resolutionAnphA.00817.a2009-09-302009-10-13RELnone
3D63 crystal structure of inorganic pyrophosphatase from burkholderia pseudomalleiBupsA.00023.a2008-05-182008-07-08RELnone
3F9I crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase rickettsia prowazekiiRiprA.00010.b2008-11-132008-11-25RELnone
3LP8 crystal structure of phosphoribosylamine-glycine ligase from ehrlichia chaffeensisEhchA.00865.a2010-02-042010-02-23RELnone
3DAH 2.3 a crystal structure of ribose-phosphate pyrophosphokinase from burkholderia pseudomalleiBupsA.00035.a2008-05-292008-06-10RELnone
3E5Y crystal structure of trmh family rna methyltransferase from burkholderia pseudomalleiBupsA.00072.a2008-08-142008-08-26RELnone
3H81 crystal structure of enoyl-coa hydratase from mycobacterium tuberculosisMytuD.00358.a2009-04-282009-05-12RELnone
3GAF 2.2a crystal structure of 7-alpha-hydroxysteroid dehydrogenase from brucella melitensisBrabA.00010.e2009-02-172009-03-17RELnone
3KGB crystal structure of thymidylate synthase 1/2 from encephalitozoon cuniculi at 2.2 a resolutionEncuA.01191.a2009-10-282009-11-10RELnone
2KE0 solution structure of peptidyl-prolyl cis-trans isomerase from burkholderia pseudomalleiBupsA.00130.a2009-01-212009-03-03RELnone
3L0D crystal structure of glyceraldehyde-3-phosphate dehydrogenase from bartonella henselae with bound nadBaheA.00617.a2009-12-092009-12-29RELnone
3FTP crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from burkholderia pseudomallei at 2.05 a resolutionBupsA.00010.a2009-01-132009-01-27RELnone
3KM3 crystal structure of eoxycytidine triphosphate deaminase from anaplasma phagocytophilum at 2.1a resolutionAnphA.00973.a2009-11-092009-11-24RELnone
3EG4 crystal structure of 2,3,4,5-tetrahydropyridine-2-carboxylate n-succinyltransferase from brucella melitensis biovar abortus 2308BrabA.00002.a2008-09-102008-09-23RELnone
3EK1 crystal structure of aldehyde dehydrogenase from brucella melitensis biovar abortus 2308BrabA.00020.a2008-09-182008-09-30RELnone
3KHW crystal structure of the large c-terminal domain of polymerase basic protein 2 from influenza virus a/mexico/indre4487/2009(h1n1)InvaE.07055.a2009-10-312010-03-09RELnone
3LNC crystal structure of guanylate kinase from anaplasma phagocytophilumAnphA.01463.a2010-02-022010-02-16RELnone
3L3B crystal structure of isoprenoid biosynthesis protein with amidotransferase-like domain from ehrlichia chaffeensis at 1.90a resolutionEhchA.01061.a2009-12-162010-01-19RELnone
3D5T crystal structure of malate dehydrogenase from burkholderia pseudomalleiBupsA.00005.a2008-05-162008-06-03RELnone
3GRP 2.1 angstrom crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from bartonella henselaeBaheA.00010.c2009-03-262009-04-07RELnone
3I3R x-ray structure dihydrofolate reductase/thymidylate synthase from babesia bovis at 2.35a resolutionBaboA.01191.a2009-06-302009-08-18RELnone
3HE2 crystal structure of enoyl-coa hydratase from mycobacterium tuberculosisMytuD.01381.a2009-05-072009-06-09RELnone
3ECD crystal structure of serine hydroxymethyltransferase from burkholderia pseudomalleiBupsA.00008.a2008-08-292008-09-09RELnone
3HN6 crystal structure of glucosamine-6-phosphate deaminase from borrelia burgdorferiBobuA.00564.a2009-05-292009-06-09RELnone
3FS2 crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from bruciella melitensis at 1.85a resolutionBrabA.00102.a2009-01-092009-01-20RELnone
3K2C crystal structure of peptidyl-prolyl cis-trans isomerase from encephalitozoon cuniculi at 1.9 a resolutionEncuA.00682.a2009-09-292009-10-13RELnone
3F0D high resolution crystal structure of 2c-methyl-d-erythritol 2,4-cyclodiphosphatase synthase from burkholderia pseudomalleiBupsA.00122.a2008-10-242008-11-04RELnone
3GWC crystal structure of mycobacterium tuberculosis thymidylate synthase x bound to fdump and fadMytuD.01655.a2009-03-312009-04-28RELnone
3EK2 crystal structure of eonyl-(acyl carrier protein) reductase from burkholderia pseudomallei 1719bBupsA.00010.b2008-09-182008-09-30RELnone
3EZO crystal structure of acyl-carrier-protein s-malonyltransferase from burkholderia pseudomallei 1710bBupsA.00141.a2008-10-232008-11-11RELnone
3HHE crystal structure of ribose-5-phosphate isomerase a from bartonella henselaeBaheA.00944.a2009-05-152009-05-26RELnone
3KNU crystal structure of trna (guanine-n1)-methyltransferase from anaplasma phagocytophilumAnphA.00316.a2009-11-122009-11-24RELnone
3JS4 crystal structure of iron superoxide dismutase from anaplasma phagocytophilumAnphA.01360.a2009-09-092009-09-22RELnone
3GVC crystal structure of probable short-chain dehydrogenase-reductase from mycobacterium tuberculosisMytuD.00472.a2009-03-302009-04-07RELnone
3IKZ crystal structure of phosphopantetheine adenylyltransferase from burkholderia pseudomalleiBupsA.00142.a2009-08-062009-08-18RELnone
3EZ4 crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase from burkholderia pseudomalleiBupsA.00112.a2008-10-222008-11-04RELnone
2KHP solution structure of glutaredoxin from brucella melitensisBrabA.00079.a2009-04-102009-05-05RELnone
3I44 crystal structure of aldehyde dehydrogenase from bartonella henselae at 2.0a resolutionBaheA.00886.a2009-07-012009-07-14RELnone
2KN9 solution structure of zinc-substituted rubredoxin b (rv3250c) from mycobacterium tuberculosis. seattle structural genomics center for infectious disease target mytud.01635.aMytuD.01635.a2009-08-202009-09-15RELnone
3IML crystal structure of s-adenosylmethionine synthetase from burkholderia pseudomalleiBupsA.00040.a2009-08-102009-09-22RELnone
3DMP 2.6 a crystal structure of uracil phosphoribosyltransferase from burkholderia pseudomalleiBupsA.00076.a2008-07-012008-07-15RELnone
3KXQ crystal structure of triosephosphate isomerase from bartonella henselae at 1.6a resolutionBaheA.01246.a2009-12-032009-12-22RELnone
3KRS structure of triosephosphate isomerase from cryptosporidium parvum at 1.55a resolutionCrpaA.01119.a2009-11-192009-12-01RELnone
3GTD 2.4 angstrom crystal structure of fumarate hydratase from rickettsia prowazekiiRiprA.00047.a2009-03-272009-07-14RELnone

Note 1:  Last updated: Mar 17 2010

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Sequence Redundancy Statistics

Table 5: Sequence Redundancy Statistics for SSGCID by Experimental Status

Sequence Identity(%)Novel Targets
Status:
Selected
Novel Targets
Status:
Cloned
Novel Targets
Status:
Expressed
Novel Targets
Status:
Purified
Novel Targets
Status:
Crystallized
Novel Targets
Status:
Crystal Structure
Novel Targets
Status:
NMR Structure
Novel Targets
Status:
in PDB
<10021461468114155220182685
<9020871438112554820182685
<7019721376108953119581684
<501487111190445316869571
<3060452147629813461563
Last updated: 10-03-08
Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in TargetDB which are in the same experimental status category and at least 20 amino acids long

Table 6:Sequence Redundancy Statistics for Structures Released by SSGCID by Year

Year Released Structures Number of Released Structures <30% Identity at Time of Release Percent(%) of Released Structures <30% Identity(%) at Time of Release
20082714
20098156
20101318
Total12176
Last updated:10-03-17
Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in the PDB which are at least 20 amino acids long
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