PSI TargetDB

Statistics Summary Report for TB Center

Last updated: Jul 2 2009



Target Status Statistics

Total number of targets deposited by TB to TargetDB: 1751

      View TB Target List

Table 1: Status Statistics for TB

Status Total Number of Targets(%) Relative to "Cloned" Targets(%) Relative to "Expressed" Targets(%) Relative to "Purified" Targets(%) Relative to "Crystallized" Targets
Cloned1286100.0---
Expressed97175.5100.0--
Soluble54642.556.2--
Purified47236.748.6100.0-
Crystallized33426.034.470.8100.0
Diffraction-quality Crystals25119.525.853.275.1
Diffraction24218.824.951.372.5
NMR Assigned23518.324.249.8-
HSQC23518.324.249.8-
Crystal Structure23418.224.149.670.1
NMR Structure20816.221.444.1-
In PDB120816.221.444.10
Work Stopped0----
Test Target9----
Other8----

Last updated: Jul 2 2009

Table 2: Status Statistics for TB by Organism

Organism Total Number1 Work Stopped Cloned Expressed Purified Crystallized Crystal Structure NMR Structure In PDB2
Bacteria175001285970472334234208208
Total Prokaryotes175001285970472334234208208
Unknown101100000
Total175101286971472334234208208

Last updated: Jul 2 2009

Note 1:   Total counts in this table may differ from total number of targets. If targtet is a hybrid complex
(for example:a complex of human and mouse polypeptides) it is counted in different organism classifications.

Note 2:   Number of targets with status "in PDB" may not be equal to number of structures determined by a project. A target may reference several PDB IDs (example: structure of the same polypeptides with different ligands). Multiple targets in TargetDB may identify the same PDB structure when a stucture is a result of collaboration between different centers and each center includes the target on its target list. back to top


Deposited Structure Statistics for TB Center

Number of Released X-Ray Structures: 375

Number of Released NMR Structures: 7

Total number of released structures from TB center in the PDB: 382

Table 3: PDB Status Statistics for Structures from TB

PDB StatusNumber of Structures
Total Deposited515
Released382
In Process133
Last updated: Jul 2 2009
Note 1:   "Total Deposited" are all structures in the PDB including structures released to the public and structures that are in the process to be released("Released on Publication" , "Released on Certain Date", etc.).

Table 4: List of Structures Deposited in the PDB by TB

Total number of structures: 515

Structures of distinct targets: 2961

1   A target may reference several PDB IDs (example: structure of the same polypeptides with different ligands).
In this case only one structure is counted to compute number of structures of distinct targets

Related PDB_ID(s): PDB_ID(s) associated with the same target in targetDB

PDB_ID TitleTarget_id Deposition DateReleased Date PDB StatusRelated PDB_ID in TargetDB
ND_3 Experimental status "in PDB", PDB ID is not providedRv1658---none
ND_30 Experimental status "in PDB", PDB ID is not providedRv1312---none
ND_93 Experimental status "in PDB", PDB ID is not providedRv3127---none
ND_134 Experimental status "in PDB", PDB ID is not providedRv1669---none
ND_102 Experimental status "in PDB", PDB ID is not providedRv1869c---none
ND_122 Experimental status "in PDB", PDB ID is not providedRv1595---none
ND_131 Experimental status "in PDB", PDB ID is not providedRv2667---none
ND_67 Experimental status "in PDB", PDB ID is not providedRv0634c---none
ND_15 Experimental status "in PDB", PDB ID is not providedRv0844c---none
ND_21 Experimental status "in PDB", PDB ID is not providedRv0436c---none
ND_44 Experimental status "in PDB", PDB ID is not providedRv0862c---none
ND_72 Experimental status "in PDB", PDB ID is not providedRv1005c---none
ND_28 Experimental status "in PDB", PDB ID is not providedRv0342---none
ND_92 Experimental status "in PDB", PDB ID is not providedRv0145---none
ND_33 Experimental status "in PDB", PDB ID is not providedRv2171---none
ND_57 Experimental status "in PDB", PDB ID is not providedRv2179c---none
ND_23 Experimental status "in PDB", PDB ID is not providedRv3254---none
ND_4 Experimental status "in PDB", PDB ID is not providedRv2726c---none
ND_5 Experimental status "in PDB", PDB ID is not providedRv2771c---none
ND_17 Experimental status "in PDB", PDB ID is not providedRv0036C---none
ND_121 Experimental status "in PDB", PDB ID is not providedRv1604---none
ND_133 Experimental status "in PDB", PDB ID is not providedRv2790c---none
ND_46 Experimental status "in PDB", PDB ID is not providedRv0553---none
ND_99 Experimental status "in PDB", PDB ID is not providedRv3705c---none
ND_20 Experimental status "in PDB", PDB ID is not providedRv2303c---none
ND_84 Experimental status "in PDB", PDB ID is not providedRv3603c---none
ND_14 Experimental status "in PDB", PDB ID is not providedRv3215---none
ND_47 Experimental status "in PDB", PDB ID is not providedRv3415c---none
ND_116 Experimental status "in PDB", PDB ID is not providedRv2210c---none
ND_107 Experimental status "in PDB", PDB ID is not providedRv3648c---none
ND_101 Experimental status "in PDB", PDB ID is not providedRv0808---none
ND_58 Experimental status "in PDB", PDB ID is not providedRv2257c---none
ND_71 Experimental status "in PDB", PDB ID is not providedRv3596c---none
ND_110 Experimental status "in PDB", PDB ID is not providedRv0757---none
ND_103 Experimental status "in PDB", PDB ID is not providedRv3923c---none
ND_49 Experimental status "in PDB", PDB ID is not providedRv0414c---none
ND_120 Experimental status "in PDB", PDB ID is not providedRv0600c---none
ND_74 Experimental status "in PDB", PDB ID is not providedRv2137c---none
ND_95 Experimental status "in PDB", PDB ID is not providedRv2059---none
ND_6 Experimental status "in PDB", PDB ID is not providedRv2460c---none
ND_75 Experimental status "in PDB", PDB ID is not providedRv3616c---none
ND_50 Experimental status "in PDB", PDB ID is not providedRv2351c---none
ND_38 Experimental status "in PDB", PDB ID is not providedRv0252---none
ND_83 Experimental status "in PDB", PDB ID is not providedRv2153c---none
ND_59 Experimental status "in PDB", PDB ID is not providedRv1211---none
ND_115 Experimental status "in PDB", PDB ID is not providedRv1350---none
ND_31 Experimental status "in PDB", PDB ID is not providedRv0688---none
ND_69 Experimental status "in PDB", PDB ID is not providedRv0275c---none
ND_104 Experimental status "in PDB", PDB ID is not providedRv2352c---none
ND_13 Experimental status "in PDB", PDB ID is not providedRv3894c---none
ND_60 Experimental status "in PDB", PDB ID is not providedRv1884c---none
ND_129 Experimental status "in PDB", PDB ID is not providedRv1499---none
ND_36 Experimental status "in PDB", PDB ID is not providedRv3248c---none
ND_82 Experimental status "in PDB", PDB ID is not providedRv0368c---none
ND_94 Experimental status "in PDB", PDB ID is not providedRv3849---none
ND_106 Experimental status "in PDB", PDB ID is not providedRv2468c---none
ND_48 Experimental status "in PDB", PDB ID is not providedRv1228---none
ND_25 Experimental status "in PDB", PDB ID is not providedRv2660c---none
ND_112 Experimental status "in PDB", PDB ID is not providedRv2294---none
ND_68 Experimental status "in PDB", PDB ID is not providedRv0981---none
ND_41 Experimental status "in PDB", PDB ID is not providedRv1730c---none
ND_85 Experimental status "in PDB", PDB ID is not providedRv3838c---none
ND_109 Experimental status "in PDB", PDB ID is not providedRv3001c---none
ND_12 Experimental status "in PDB", PDB ID is not providedRv2890c---none
ND_39 Experimental status "in PDB", PDB ID is not providedRv1264---none
ND_73 Experimental status "in PDB", PDB ID is not providedRv0212c---none
ND_22 Experimental status "in PDB", PDB ID is not providedRv3708c---none
ND_118 Experimental status "in PDB", PDB ID is not providedRv2427c---none
ND_117 Experimental status "in PDB", PDB ID is not providedRv0886---none
ND_24 Experimental status "in PDB", PDB ID is not providedRv2108---none
ND_64 Experimental status "in PDB", PDB ID is not providedRv2917---none
ND_11 Experimental status "in PDB", PDB ID is not providedRv2175c---none
ND_51 Experimental status "in PDB", PDB ID is not providedRv0363c---none
ND_40 Experimental status "in PDB", PDB ID is not providedRv0827c---none
ND_105 Experimental status "in PDB", PDB ID is not providedRv3286c---none
ND_127 Experimental status "in PDB", PDB ID is not providedRv0490---none
ND_37 Experimental status "in PDB", PDB ID is not providedRv0304c---none
ND_78 Experimental status "in PDB", PDB ID is not providedRv1251c---none
ND_7 Experimental status "in PDB", PDB ID is not providedRv3256c---none
ND_96 Experimental status "in PDB", PDB ID is not providedRv0890c---none
ND_80 Experimental status "in PDB", PDB ID is not providedRv0323c---none
ND_18 Experimental status "in PDB", PDB ID is not providedRv0990c---none
ND_52 Experimental status "in PDB", PDB ID is not providedRv1085c---none
ND_111 Experimental status "in PDB", PDB ID is not providedRv3789---none
ND_62 Experimental status "in PDB", PDB ID is not providedRv1201c---none
ND_89 Experimental status "in PDB", PDB ID is not providedRv3118---none
ND_9 Experimental status "in PDB", PDB ID is not providedRv1028c---none
ND_63 Experimental status "in PDB", PDB ID is not providedRv3753c---none
ND_10 Experimental status "in PDB", PDB ID is not providedRv1966---none
ND_43 Experimental status "in PDB", PDB ID is not providedRv2416c---none
ND_88 Experimental status "in PDB", PDB ID is not providedRv1124---none
ND_34 Experimental status "in PDB", PDB ID is not providedRv2340c---none
ND_119 Experimental status "in PDB", PDB ID is not providedRv0002---none
ND_76 Experimental status "in PDB", PDB ID is not providedRv1184c---none
ND_114 Experimental status "in PDB", PDB ID is not providedRv1931c---none
ND_61 Experimental status "in PDB", PDB ID is not providedRv2919c---none
ND_130 Experimental status "in PDB", PDB ID is not providedRv0278c---none
ND_27 Experimental status "in PDB", PDB ID is not providedRv0871---none
ND_77 Experimental status "in PDB", PDB ID is not providedRv3464---none
ND_8 Experimental status "in PDB", PDB ID is not providedRv0867c---none
ND_125 Experimental status "in PDB", PDB ID is not providedRv2682c---none
ND_35 Experimental status "in PDB", PDB ID is not providedRV3146---none
ND_55 Experimental status "in PDB", PDB ID is not providedRv2988c---none
ND_16 Experimental status "in PDB", PDB ID is not providedRv0777---none
ND_87 Experimental status "in PDB", PDB ID is not providedRv3566c---none
ND_100 Experimental status "in PDB", PDB ID is not providedRv3426---none
ND_53 Experimental status "in PDB", PDB ID is not providedRv3015c---none
ND_70 Experimental status "in PDB", PDB ID is not providedRv2512c---none
ND_26 Experimental status "in PDB", PDB ID is not providedRv1027c---none
ND_66 Experimental status "in PDB", PDB ID is not providedRv0309---none
ND_79 Experimental status "in PDB", PDB ID is not providedRv0170---none
ND_113 Experimental status "in PDB", PDB ID is not providedRv2891---none
ND_42 Experimental status "in PDB", PDB ID is not providedRv3302c---none
ND_124 Experimental status "in PDB", PDB ID is not providedRv3013---none
ND_91 Experimental status "in PDB", PDB ID is not providedRv3835---none
ND_108 Experimental status "in PDB", PDB ID is not providedRv1814---none
ND_98 Experimental status "in PDB", PDB ID is not providedRv1706c---none
ND_54 Experimental status "in PDB", PDB ID is not providedRv3922c---none
ND_56 Experimental status "in PDB", PDB ID is not providedRv0601c---none
ND_126 Experimental status "in PDB", PDB ID is not providedRv3682---none
ND_65 Experimental status "in PDB", PDB ID is not providedRv3718c---none
ND_2 Experimental status "in PDB", PDB ID is not providedRv3735---none
ND_97 Experimental status "in PDB", PDB ID is not providedRv0384c---none
ND_86 Experimental status "in PDB", PDB ID is not providedRv3647c---none
ND_128 Experimental status "in PDB", PDB ID is not providedRv1202---none
ND_32 Experimental status "in PDB", PDB ID is not providedRv0360c---none
ND_45 Experimental status "in PDB", PDB ID is not providedRv0772---none
ND_123 Experimental status "in PDB", PDB ID is not providedRv0989c---none
ND_132 Experimental status "in PDB", PDB ID is not providedRv0783c---none
ND_81 Experimental status "in PDB", PDB ID is not providedRv2449C---none
ND_19 Experimental status "in PDB", PDB ID is not providedRv2245---none
ND_90 Experimental status "in PDB", PDB ID is not providedRv3396c---none
ND_29 Experimental status "in PDB", PDB ID is not providedRv0491---none
2HHI the solution structure of antigen mpt64 from mycobacterium tuberculosis defines a novel class of beta-grasp proteinsRv1980c2006-06-282006-12-05RELnone
2I6U crystal structure of ornithine carbamoyltransferase complexed with carbamoyl phosphate and l-norvaline from mycobacterium tuberculosis (rv1656) at 2.2 aRv16562006-08-292007-06-26REL2P2G
1YBT mycobacterium tuberculosis adenylyl cyclase, rv1900c chdRv1900c2004-12-212005-02-15REL1YBU
1YL5 crystal structure of mycobacterium tuberculosis dihydrodipicolinate reductase (rv2773c) (crystal form a)Rv2773c NON-XMTB:rv2773c2005-01-192006-01-17RELnone
2C2Y three dimensional structure of bifunctional methylenetetrahydrofolate dehydrogenase-cyclohydrolase from mycobacterium tuberculosisRv3356c2005-09-302005-10-13RELnone
2NYX crystal structure of rv1404 from mycobacterium tuberculosisRv1404 ISFI:ISFI1552006-11-212006-12-05RELnone
2VBW feast or famine regulatory protein (rv3291c)from m. tuberculosis complexed with l-phenylalanineRv3291c2007-09-182007-11-06RELnone
2IYW shikimate kinase from mycobacterium tuberculosis in complex with mgatp, open lid (conf. b)Rv2539c2006-07-222006-10-18RELnone
1PZS crystal structure of a cu-zn superoxide dismutase from mycobacterium tuberculosis at 1.63 resolutionRv04322003-07-142004-07-27RELnone
2Z76 x-ray crystal structure of rv0760c from mycobacterium tuberculosis at 1.82 angstrom resolutionRv0760c2007-08-162007-09-18RELnone
2FVH crystal structure of rv1848, a urease gamma subunit urea (urea amidohydrolase), from mycobacterium tuberculosisRv18482006-01-302006-02-07RELnone
1F8I crystal structure of isocitrate lyase:nitropropionate:glyoxylate complex from mycobacterium tuberculosisRv04672000-06-302000-12-30RELnone
2A7X crystal structure of a pantothenate synthetase complexed with ampRv3602c2005-07-062006-02-21RELnone
1N2H crystal structure of a pantothenate synthetase from m. tuberculosis in complex with a reaction intermediate, pantoyl adenylateRv3602c2002-10-222003-04-22RELnone
1UP0 structure of the endoglucanase cel6 from mycobacterium tuberculosis in complex with cellobiose at 1.75 angstromRv00622003-09-262004-11-18RELnone
1XXX crystal structure of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosisRv2753c NON-XMTB:rv2753c2004-11-092006-02-14RELnone
2IMZ crystal structure of mtu reca intein splicing domainRv2737c2006-10-052007-05-01RELnone
1UE5 crystal structure of the single-stranded dna-binding protein from mycobacterium tuberculosisRv00542003-05-092004-02-10RELnone
1RFE crystal structure of conserved hypothetical protein rv2991 from mycobacterium tuberculosisRv29912003-11-082004-12-28RELnone
2BET structure of mycobacterium tuberculosis ribose-5-phosphate isomerase, rpib, rv2465c, in complex with 4-phospho-d-erythronate.Rv2465c2004-11-302004-12-03RELnone
2GKM crystal structure of mycobacterium tuberculosis trhbn tyrb10phe mutantRv1542C2006-04-032006-09-19RELnone
1WA8 solution structure of the cfp-10.esat-6 complex. major virulence determinants of pathogenic mycobacteriaRv38752004-10-252005-06-27RELnone
1N8I biochemical and structural studies of malate synthase from mycobacterium tuberculosisRv1837c2002-11-202002-12-18REL1N8W 2GQ3
1TEE crystal structure of c205f mutant of pks18 from mycobacterium tuberculosisRv13722004-05-252004-08-03RELnone
2IN0 crystal structure of mtu reca intein splicing domainRv2737c2006-10-052007-05-01RELnone
1YK3 crystal structure of rv1347c from mycobacterium tuberculosisRv1347c2005-01-162005-02-01RELnone
2IRX crystal structure of the polymerase domain from mycobacterium tuberculosis ligase d with gtp and manganese.Rv09382006-10-162007-01-02RELnone
1HX5 crystal structure of m. tuberculosis chaperonin-10Rv3418c2001-01-112001-08-08REL1P3H
1ZLK crystal structure of the mycobacterium tuberculosis hypoxic response regulator dosr c-terminal domain-dna complexRv3133c2005-05-062006-01-31RELnone
2H7M crystal structure of mycobacterium tuberculosis enoyl reductase (inha) complexed with 1-cyclohexyl-n-(3,5-dichlorophenyl)-5-oxopyrrolidine-3-carboxamideRv14842006-06-022006-10-31RELnone
2BES structure of mycobacterium tuberculosis ribose-5-phosphate isomerase, rpib, rv2465c, in complex with 4-phospho-d-erythronohydroxamic acid.Rv2465c2004-11-302004-12-03RELnone
1WQF crystal structure of ribosome recycling factor from mycobacterium tuberculosisRv2882c2004-09-282005-02-22REL1WQG 1WQH
2VBX feast or famine regulatory protein (rv3291c)from m. tuberculosis complexed with l-phenylalanineRv3291c2007-09-182007-11-06RELnone
1U5V structure of cite complexed with triphosphate group of atp form mycobacterium tuberculosisRv2498c2004-07-282004-10-12RELnone
2JCX x-ray structure of mutant 1-deoxy-d-xylulose 5-phosphate reductoisomerase, dxr, rv2870c, from mycobacterium tuberculosis, in complex with fosmidomycin and nadphRv2870c2007-01-042007-05-08RELnone
2IRY crystal structure of the polymerase domain from mycobacterium tuberculosis ligase d with dgtp and manganese.Rv09382006-10-162007-01-02RELnone
1PM7 rmlc (dtdp-6-deoxy-d-xylo-4-hexulose 3,5-epimerase)structure from mycobacterium tuberculosis and inhibitor design. the apo structure.Rv34652003-06-102003-12-09REL1UPI
2VC0 feast or famine regulatory protein (rv3291c)from m. tuberculosis complexed with l-leucineRv3291c2007-09-182007-11-06RELnone
1N8W biochemical and structural studies of malate synthase from mycobacterium tuberculosisRv1837c2002-11-212002-12-18RELnone
1YBU mycobacterium tuberculosis adenylyl cyclase rv1900c chd, in complex with a substrate analog.Rv1900c2004-12-212005-02-15RELnone
1QPN quinolinate phosphoribosyl transferase from mycobacterium tuberculosis in complex with ncnnRv15961998-11-201998-11-25REL1QPO 1QPQ 1QPR
2CJH lysine aminotransferase from m. tuberculosis in the internal aldimine form with bound substrate 2-ketoglutarateRv3290c2006-04-032006-08-14RELnone
1N2G crystal structure of a pantothenate synthetase from m. tuberculosis in complex with ampcppRv3602c2002-10-222003-04-22RELnone
2CJD lysine aminotransferase from m. tuberculosis in external aldimine formRv3290c2006-03-312006-08-14RELnone
1GSI crystal structure of mycobacterium tuberculosis thymidylate kinase complexed with thymidine monophosphate (tmp)Rv3247c2002-01-032002-03-28RELnone
1ZNX crystal structure of mycobacterium tuberculosis guanylate kinase in complex with gmpRv13892005-05-122005-11-29RELnone
1SM8 m. tuberculosis dutpase complexed with chromium and dutpRv2697c2004-03-082004-03-16RELnone
2GLN crystal structure of mycobacterium tuberculosis trhbn, glne11ala mutantRv1542C2006-04-052006-09-19RELnone
1MRN crystal structure of mycobacterium tuberculosis thymidylate kinase complexed with bisubstrate inhibitor (tp5a)Rv3247c2002-09-182003-01-07RELnone
2NQT crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (rv1652) from mycobacterium tuberculosis at 1.58 a resolutionRv16522006-10-312006-11-28RELnone
1N5K crystal structure of mycobacterium tuberculosis thymidylate kinase crystallized in sodium malonate (resolution 2.1 a)Rv3247c2002-11-062003-04-15RELnone
1MO4 reca-atp-gamma-s complexRv2737c2002-09-072003-02-18RELnone
1S4Q crystal structure of guanylate kinase from mycobacterium tuberculosis (rv1389)Rv13892004-01-162004-01-27REL1Z8F 1ZNW 1ZNX 1ZNY
1YL7 the crystal structure of mycobacterium tuberculosis dihydrodipicolinate reductase (rv2773c) in complex with nadh (crystal form c)Rv2773c NON-XMTB:rv2773c2005-01-192006-01-17RELnone
1KPG crystal structure of mycolic acid cyclopropane synthase cmaa1 complexed with sah and ctabRv3392c2001-12-302002-01-11RELnone
1SJ2 crystal structure of mycobacterium tuberculosis catalase-peroxidaseRv1908C2004-03-022004-07-20REL2CCA 2CCD
1SLH mycobacterium tuberculosis dutpase complexed with magnesium and dudpRv2697c2004-03-052004-03-16RELnone
2IYX shikimate kinase from mycobacterium tuberculosis in complex with shikimate and so4Rv2539c2006-07-222006-10-11RELnone
2A2J crystal structure of a putative pyridoxine 5'-phosphate oxidase (rv2607) from mycobacterium tuberculosisRv26072005-06-222005-08-23RELnone
1S8N crystal structure of rv1626 from mycobacterium tuberculosisRv1626 NON-XMTB:rv16262004-02-032004-09-21REL1SD5
1Z8F guanylate kinase double mutant a58c, t157c from mycobacterium tuberculosis (rv1389)Rv13892005-03-302005-04-12RELnone
1KPI crystal structure of mycolic acid cyclopropane synthase cmaa2 complexed with sah and dddmabRv0503c2001-12-302002-01-11RELnone
1OZP crystal structure of rv0819 from mycobacterium tuberculosis mshd-mycothiol synthase acetyl-coenzyme a complex.Rv08192003-04-092003-09-09REL1P0H 2C27
1ZEL crystal structure of rv2827c protein from mycobacterium tuberculosisRv2827c NON-XMTB:rv2827c2005-04-192006-05-02RELnone
1NKT crystal structure of the seca protein translocation atpase from mycobacterium tuberculosis complex with adpbsRv3240c2003-01-032003-03-04REL1NL3
1L4U crystal structure of shikimate kinase from mycobacterium tuberculosis in complex with mgadp and pt(ii) at 1.8 angstrom resolutionRv2539c2002-03-052002-06-12REL1L4Y 1U8A 1ZYU 2DFN 2DFT 2G1J 2G1K 2IYQ 2IYR 2IYS 2IYT 2IYU 2IYV 2IYW 2IYX
1K44 mycobacterium tuberculosis nucleoside diphosphate kinaseRv2445c2001-10-052002-05-15RELnone
1YS7 crystal structure of the response regulator protein prra comlexed with mg2+Rv0903c NON-XMTB:rv0903c2005-02-072006-02-07RELnone
1U13 crystal structure analysis of the c37l/c151t/c442a-triple mutant of cyp51 from mycobacterium tuberculosisRv0764c2004-07-142004-07-27RELnone
1FX7 crystal structure of the iron-dependent regulator (ider) from mycobacterium tuberculosisRv27112000-09-252001-03-07RELnone
1LQT a covalent modification of nadp+ revealed by the atomic resolution structure of fpra, a mycobacterium tuberculosis oxidoreductaseRv31062002-05-132002-07-31REL1LQU 2C7G
1UP2 structure of the endoglucanase cel6 from mycobacterium tuberculosis in complex with glucose-isofagomine at 1.9 angstromRv00622003-09-262004-11-18RELnone
2G5F the structure of mbti from mycobacterium tuberculosis, the first enzyme in the synthesis of mycobactin, reveals it to be a salicylate synthaseRv2386c2006-02-222006-09-05REL2I6Y
2IYQ shikimate kinase from mycobacterium tuberculosis in complex with shikimate and adpRv2539c2006-07-212006-10-11RELnone
1GTV crystal structure of mycobacterium tuberculosis thymidylate kinase complexed with thymidine-5'-diphosphate (tdp)Rv3247c2002-01-212002-03-28RELnone
2GKN crystal structure of mycobacterium tuberculosis trhbn, glne11val mutantRv1542C2006-04-032006-09-19RELnone
1BVR m.tb. enoyl-acp reductase (inha) in complex with nad+ and c16-fatty-acyl-substrateRv14841998-09-171999-09-17REL1ENY 1ENZ 1P44 1P45 1ZID 2AQ8 2B35 2B36 2B37 2H7I 2H7L 2H7M 2H7N 2H7P 2NV6
1EYE 1.7 angstrom resolution crystal structure of 6-hydroxymethyl-7,8-dihydropteroate synthase (dhps) from mycobacterium tuberculosis in complex with 6-hydroxymethylpterin monophosphateRv3608c2000-05-052000-10-11RELnone
1U9N crystal structure of the transcriptional regulator ethr in a ligand bound conformation opens therapeutic perspectives against tuberculosis and leprosyRv38552004-08-102004-11-16RELnone
2JCV x-ray structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase, dxr, rv2870c, from mycobacterium tuberculosis, in complex with fosmidomycin and nadphRv2870c2007-01-042007-05-08REL2JCX 2JCY 2JCZ 2JD0 2JD1 2JD2
2H7L crystal structure of mycobacterium tuberculosis enoyl reductase (inha) complexed with n-(3-bromophenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamideRv14842006-06-022006-10-31RELnone
1YWF crystal structure of mycobacterium tuberculosis protein tyrosine phosphatase ptpbRv0153c2005-02-172005-11-22RELnone
1SJP mycobacterium tuberculosis chaperonin60.2Rv04402004-03-042004-12-07RELnone
1ZTB crystal structure of chorismate synthase from mycobacterium tuberculosisRv2540c2005-05-262006-05-16REL2G85
1T56 crystal structure of tetr family repressor m. tuberculosis ethrRv38552004-05-032004-07-27REL1U9N 1U9O
2H7P crystal structure of mycobacterium tuberculosis enoyl reductase (inha) complexed with n-(3-chloro-2-methylphenyl)-1-cyclohexyl- 5-oxopyrrolidine-3-carboxamideRv14842006-06-022006-10-31RELnone
2P2G crystal structure of ornithine carbamoyltransferase from mycobacterium tuberculosis (rv1656): orthorhombic formRv16562007-03-072007-07-03RELnone
1Y25 structure of mycobacterial thiol peroxidase tpxRv19322004-11-202005-11-20RELnone
1QPQ structure of quinolinic acid phosphoribosyltransferase from mycobacterium tuberculosis: a potential tb drug targetRv15961998-11-201998-11-25RELnone
1ZLJ crystal structure of the mycobacterium tuberculosis hypoxic response regulator dosr c-terminal domainRv3133c2005-05-062006-01-31REL1ZLK
1MOP crystal structure of a pantothenate synthetase from m. tuberculosisRv3602c2002-09-092003-03-11REL1N2B 1N2E 1N2G 1N2H 1N2I 1N2J 1N2O 2A7X 2A84 2A86 2A88
1WQH crystal structure of ribosome recycling factor from mycobacterium tuberculosisRv2882c2004-09-292005-02-22RELnone
1TXO crystal structure of the mycobacterium tuberculosis serine/threonine phosphatase pstp/ppp at 1.95 a.Rv0018c2004-07-052004-11-23RELnone
1F61 crystal structure of isocitrate lyase from mycobacterium tuberculosisRv04672000-06-192000-08-30REL1F8I 1F8M
2C2X three dimensional structure of bifunctional methylenetetrahydrofolate dehydrogenase-cyclohydrolas from mycobacterium tuberculosisRv3356c2005-09-302005-10-13REL2C2Y
1GN6 g152a mutant of mycobacterium tuberculosis iron-superoxide dismutase.Rv38462001-10-032001-10-05RELnone
1V0J udp-galactopyranose mutase from mycobacterium tuberculosisRv3809c2004-03-302005-01-26RELnone
2GEU pantothenate kinase from mycobacterium tuberculosis (mtpank) in complex with a coenzyme a derivative, form-ii (rt)Rv1092c2006-03-202006-06-06RELnone
1SGV structure of trna psi55 pseudouridine synthase (trub)Rv2793c2004-01-282004-02-10RELnone
1U8A crystal structure of mycobacterium tuberculosis shikimate kinase in complex with shikimate and adp at 2.15 angstrom resolutionRv2539c2004-08-052004-10-19RELnone
1RTE x-ray structure of cyanide derivative of truncated hemoglobin n (trhbn) from mycobacterium tuberculosisRv1542C2003-12-102004-07-27RELnone
1UP3 structure of the endoglucanase cel6 from mycobacterium tuberculosis in complex with methyl-cellobiosyl-4-deoxy-4-thio-beta-d-cellobioside at 1.6 angstromRv00622003-09-262004-11-18RELnone
1P0H crystal structure of rv0819 from mycobacterium tuberculosis mshd-mycothiol synthase coenzyme a complexRv08192003-04-102003-09-09RELnone
2CCA crystal structure of the catalase-peroxidase (katg) and s315t mutant from mycobacterium tuberculosisRv1908C2006-01-162006-01-19RELnone
1P44 targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural dataRv14842003-04-212003-09-16RELnone
2Z2K crystal structure of peptidyl-trna hydrolase from mycobacterium tuberculosisRv1014c2007-05-222007-07-24RELnone
2C27 the structure of mycothiol synthase in complex with des- acetylmycothiol and coenzymea.Rv08192005-09-262005-12-01RELnone
1XVQ crystal structure of thiol peroxidase from mycobacterium tuberculosisRv19322004-10-282004-12-07REL1Y25
2A7Y solution structure of the conserved hypothetical protein rv2302 from the bacterium mycobacterium tuberculosisRv23022005-07-062005-08-23RELnone
2FP1 secreted chorismate mutase from mycobacterium tuberculosisRv1885c2006-01-152006-03-28RELnone
1DG5 dihydrofolate reductase of mycobacterium tuberculosis complexed with nadph and trimethoprimRv2763c1999-11-232000-03-09RELnone
1VS0 crystal structure of the ligase domain from m. tuberculosis ligd at 2.4aRv09382006-01-272006-02-28REL2IRX 2IRY
1LQU mycobacterium tuberculosis fpra in complex with nadphRv31062002-05-132002-07-31RELnone
1DG7 dihydrofolate reductase of mycobacterium tuberculosis complexed with nadph and 4-bromo wr99210Rv2763c1999-11-232000-03-09RELnone
2VBY feast or famine regulatory protein (rv3291c)from m. tuberculosis complexed with l-tyrosineRv3291c2007-09-182007-11-06RELnone
2G1J crystal structure of mycobacterium tuberculosis shikimate kinase at 2.0 angstrom resolutionRv2539c2006-02-142006-07-18RELnone
2BI0 x-ray structure of a conserved hypothetical protein, rv0216, from mycobacterium tuberculosis.Rv0216 NON-SPINE:rv02162005-01-202005-04-25RELnone
1GN3 h145q mutant of mycobacterium tuberculosis iron-superoxide dismutase.Rv38462001-10-022001-10-05RELnone
2NV6 mycobacterium tuberculosis inha (s94a) bound with inh-nad adductRv14842006-11-102006-11-21RELnone
1G18 reca-adp-alf4 complexRv2737c2000-10-112000-12-11REL1G19 1MO3 1MO4 1MO5 1MO6 2IMZ 2IN0 2IN8 2IN9
1NL3 crystal structure of the seca protein translocation atpase from mycobacterium tuberculosis in apo formRv3240c2003-01-062003-03-04RELnone
2ASB structure of a mycobacterium tuberculosis nusa-rna complexRv2841c2005-08-232005-10-11RELnone
2G38 a pe/ppe protein complex from mycobacterium tuberculosisRv2430c TB:Rv2431c ISFI:ISFI141 ISFI:ISFI1422006-02-172006-03-14RELnone
1ZNW crystal structure of unliganded form of mycobacterium tuberculosis guanylate kinaseRv13892005-05-122005-11-29RELnone
2CIN lysine aminotransferase from m. tuberculosis in the internal aldimine formRv3290c2006-03-242006-08-14REL2CJD 2CJG 2CJH
1N2E crystal structure of a pantothenate synthetase from m. tuberculosis in complex with ampcpp and pantoateRv3602c2002-10-222003-04-22RELnone
2FWV crystal structure of rv0813Rv0813c2006-02-032006-08-03RELnone
2HH7 crystal structure of cu(i) bound csor from mycobacterium tuberculosis.Rv09672006-06-272006-12-05RELnone
2A15 x-ray crystal structure of rv0760 from mycobacterium tuberculosis at 1.68 angstrom resolutionRv0760c2005-06-172005-10-11REL2Z76 2Z77 2Z7A
3BUE crystal structure of the c-terminal domain hexamer of argr from mycobacterium tuberculosisRv16572008-01-022008-01-22RELnone
2IN9 crystal structure of mtu reca intein, splicing domainRv2737c2006-10-062007-05-01RELnone
2GQ2 mycobacterium tuberculosis thyx-nadp complexRv2754c2006-04-192006-06-27RELnone
1RII crystal structure of phosphoglycerate mutase from m. tuberculosisRv04892003-11-172004-10-05RELnone
1N2O crystal structure of pantothenate synthetase from m. tuberculosis, low occupancy of beta-alanine at the pantoate binding sitesRv3602c2002-10-232003-04-23RELnone
1HZP crystal structure of the myobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase iiiRv0533c2001-01-252001-06-13REL1M1M 2AHB 2AJ9
2GP6 x-ray crystal structure of mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase ii (mtkasb)Rv22462006-04-172006-07-18RELnone
1N4G structure of cyp121, a mycobacterial p450, in complex with iodopyrazoleRv22762002-10-312003-02-04RELnone
2BVC crystal structure of mycobacterium tuberculosis glutamine synthetase in complex with a transition state mimicRv22202005-06-232005-07-07RELnone
1P4S solution structure of mycobacterium tuberculosis adenylate kinaseRv07332003-04-242004-01-20RELnone
2GQ3 mycobacterium tuberculosis malate synthase in complex with magnesium, malate, and coenzyme aRv1837c2006-04-192006-08-15RELnone
2FGG crystal structure of rv2632cRv2632c2005-12-212006-02-14RELnone
2HYX structure of the c-terminal domain of dipz from mycobacterium tuberculosisRv28742006-08-082007-07-17RELnone
2DFN structure of shikimate kinase from mycobacterium tuberculosis complexed with adp and shikimate at 1.9 angstrons of resolutionRv2539c2006-03-032006-09-03RELnone
2VBZ feast or famine regulatory protein (rv3291c)from m. tuberculosis complexed with l-tryptophanRv3291c2007-09-182007-11-06RELnone
1P3H crystal structure of the mycobacterium tuberculosis chaperonin 10 tetradecamerRv3418c2001-06-272001-09-05RELnone
1U8R crystal structure of an ider-dna complex reveals a conformational change in activated ider for base-specific interactionsRv27112004-08-062004-10-05RELnone
2F6L x-ray structure of chorismate mutase from mycobacterium tuberculosisRv1885c2005-11-292005-12-13RELnone
2JEK crystal structure of the conserved hypothetical protein rv1873 from mycobacterium tuberculosis at 1.38 aRv18732005-09-212005-10-11RELnone
2H5X ruva from mycobacterium tuberculosisRv2593c2006-05-282006-08-15RELnone
1DQZ crystal structure of antigen 85c from mycobacterium tuberculosisRv0129c2000-01-052000-07-12RELnone
1HTO crystallographic structure of a relaxed glutamine synthetase from mycobacterium tuberculosisRv22202001-01-012002-07-24REL1HTQ 2BVC
1USL structure of mycobacterium tuberculosis ribose-5-phosphate isomerase, rpib, rv2465c, complexed with phosphate.Rv2465c NON-SPINE:rv2465c2003-11-252004-01-02REL2BES 2BET
1ZJ8 structure of mycobacterium tuberculosis nira proteinRv2391 NON-SPINE:Mtb12005-04-282005-05-31REL1ZJ9
1W66 title withheldRv2217 NON-XMTB:rv22172004-08-132005-12-08RELnone
1NYO solution structure of the antigenic tb protein mpt70/mpb70Rv28752003-02-132003-08-19RELnone
1YSR crystal structure of atp binding domain of prrb from mycobacterium tuberculosisRv0902c NON-XMTB:rv0902c2005-02-092005-07-12RELnone
1TED crystal structure of a type iii polyketide synthase pks18 from mycobacterium tuberculosisRv13722004-05-252004-08-03REL1TEE
1E9X cytochrome p450 14 alpha-sterol demethylase (cyp51) from mycobacterium tuberculosis in complex with 4-phenylimidazoleRv0764c2000-10-302000-11-01REL1EA1 1H5Z 1U13 1X8V 2BZ9
1PC3 crystal structure of the extracellular phosphate abc transport receptor (psts-1) and immunodominant antigen of m. tuberculosis.Rv09342003-05-152004-05-18RELnone
2JD0 x-ray structure of mutant 1-deoxy-d-xylulose 5-phosphate reductoisomerase, dxr, rv2870c, from mycobacterium tuberculosis, in complex with nadphRv2870c2007-01-042007-05-08RELnone
2FP2 secreted chorismate mutase from mycobacterium tuberculosisRv1885c2006-01-152006-03-28RELnone
1Z6K citrate lyase beta subunit complexed with oxaloacetate and magnesium from m. tuberculosisRv2498c2005-03-222005-05-03RELnone
1SMC mycobacterium tuberculosis dutpase complexed with dutp in the absence of metal ion.Rv2697c2004-03-092004-03-16RELnone
1KP9 crystal structure of mycolic acid cyclopropane synthase cmaa1, apo-formRv3392c2001-12-302002-01-11REL1KPG 1KPH
2A88 crystal structure of a pantothenate synthetase, apo enzyme in c2 space groupRv3602c2005-07-072006-02-21RELnone
2G2D crystal structure of a putative pduo-type atp:cobalamin adenosyltransferase from mycobacterium tuberculosisRv1314c ISFI:ISFI152006-02-152006-03-28RELnone
2BMX mycobacterium tuberculosis ahpcRv2428 NON-SPINE:IPRv2428PALZ2005-03-162005-05-10RELnone
2QBV crystal structure of intracellular chorismate mutase from mycobacterium tuberculosisRv0948c2007-06-182007-06-26RELnone
1KLP the solution structure of acyl carrier protein from mycobacterium tuberculosisRv22442001-12-122002-06-07RELnone
2BM5 the structure of mfpa (rv3361c, p21 crystal form). the pentapeptide repeat protein from mycobacterium tuberculosis folds as a right- handed quadrilateral beta-helix.Rv3361c2005-03-092005-06-07RELnone
2IN8 crystal structure of mtu reca intein, splicing domainRv2737c2006-10-062007-05-01RELnone
1SR9 crystal structure of leua from mycobacterium tuberculosisRv37102004-03-222004-05-18RELnone
2FHG crystal structure of mycobacterial tuberculosis proteasomeRv2109c2005-12-232006-02-28REL2FHH
2AQ6 x-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 1.7 a resolutionRv11552005-08-172005-08-30RELnone
1SNF mycobacterium tuberculosis dutpase complexed with magnesium and deoxyuridine 5'-monophosphateRv2697c2004-03-102004-03-16RELnone
1M1M x-ray crystal structure of mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase iii (mtfabh)Rv0533c2002-06-192002-07-17RELnone
1NFQ rv2002 gene product from mycobacterium tuberculosisRv20022002-12-152002-12-30RELnone
1XDI crystal structure of lpda (rv3303c) from mycobacterium tuberculosisRv3303c2004-09-062004-10-19RELnone
1IDR crystal structure of the truncated-hemoglobin-n from mycobacterium tuberculosisRv1542C2001-04-052001-08-22REL1RTE 1S56 1S61 2GKM 2GKN 2GL3 2GLN
1XFC the 1.9 a crystal structure of alanine racemase from mycobacterium tuberculosis contains a conserved entryway into the active siteRv3423c2004-09-142005-08-16RELnone
2CJG lysine aminotransferase from m. tuberculosis in bound pmp formRv3290c2006-04-012006-08-14RELnone
1Q7T rv1170 (mshb) from mycobacterium tuberculosisRv11702003-08-202004-01-13RELnone
1W2H crystal structure of mycobacterium tuberculosis thymidylate kinase complexed with azidothymidine monophosphate (azt-mp) (2.0 a resolution)Rv3247c2004-07-062005-01-12RELnone
1ZNY crystal structure of mycobacterium tuberculosis guanylate kinase in complex with gdpRv13892005-05-122005-11-29RELnone
1XSF solution structure of a resuscitation promoting factor domain from mycobacterium tuberculosisRv10092004-10-192005-02-15RELnone
1Z9W tetrameric structure of apo-7,8-dihydroneopterin aldolase from mycobacterium tuberculosisRv3607c2003-10-212004-11-02RELnone
2VC1 feast or famine regulatory protein (rv3291c)from m. tuberculosis complexed with l-methionineRv3291c2007-09-182007-11-06RELnone
2BM4 the structure of mfpa (rv3361c, c2 crystal form). the pentapeptide repeat protein from mycobacterium tuberculosis folds as a right- handed quadrilateral beta-helix.Rv3361c2005-03-092005-06-07REL2BM5 2BM6 2BM7
2I3G crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (rv1652) from mycobacterium tuberculosis in complex with nadp+.Rv16522006-08-182006-09-05RELnone
2H7N crystal structure of mycobacterium tuberculosis enoyl reductase (inha) complexed with n-(5-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamideRv14842006-06-022006-10-31RELnone
1N2B crystal structure of a pantothenate synthetase from m. tuberculosis in complex with ampcpp and pantoate, higher occupancy of pantoate and lower occupancy of ampcpp in subunit aRv3602c2002-10-222003-04-22RELnone
2GWR crystal structure of the response regulator protein mtra from mycobacterium tuberculosisRv3246c2006-05-052006-05-23RELnone
1X8V estriol-bound and ligand-free structures of sterol 14alpha-demethylase (cyp51)Rv0764c2004-08-182004-11-23RELnone
1Y6X the 1.25 a resolution structure of phosphoribosyl-atp pyrophosphohydrolase from mycobacterium tuberculosisRv2122c2004-12-072005-03-01RELnone
1YGY crystal structure of d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosisRv2996c2005-01-052005-01-25RELnone
2VG0 rv1086 citronelly pyrophosphate complexRv10862007-11-072007-11-13RELnone
3B4T crystal structure of mycobacterium tuberculosis rnase ph, the mycobacterium tuberculosis structural genomics consortium target rv1340Rv13402007-10-242007-11-20RELnone
2B7O the structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosisRv2178c2005-10-052005-10-18RELnone
2I3A crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (rv1652) from mycobacterium tuberculosisRv16522006-08-172006-08-29REL2I3G 2NQT
1RLU mycobacterium tuberculosis ftsz in complex with gtp-gamma-sRv2150c2003-11-262004-08-31REL1RQ2 1RQ7
1Q74 the crystal structure of 1d-myo-inosityl 2-acetamido-2-deoxy-alpha-d-glucopyranoside deacetylase (mshb)Rv11702003-08-152003-12-02REL1Q7T
1NFF crystal structure of rv2002 gene product from mycobacterium tuberculosisRv20022002-12-142002-12-30REL1NFQ 1NFR
1ZJ9 structure of mycobacterium tuberculosis nira proteinRv23912005-04-282005-05-31RELnone
1WQG crystal structure of ribosome recycling factor from mycobacterium tuberculosisRv2882c2004-09-292005-02-22RELnone
2FSX crystal structure of rv0390 from m. tuberculosisRv03902006-01-232006-02-07RELnone
2IJ7 structure of mycobacterium tuberculosis cyp121 in complex with the antifungal drug fluconazoleRv22762006-09-292006-11-07RELnone
1W0D the high resolution structure of mycobacterium tuberculosis leub (rv2995c)Rv2995c NON-XMTB:rv2995c2004-06-032004-12-14RELnone
1ZZO structure of mtb dsbf in its oxidized form.Rv16772005-06-142005-07-26RELnone
2B37 crystal structure of mycobacterium tuberculosis enoyl reductase (inha) inhibited by 5-octyl-2-phenoxyphenolRv14842005-09-192006-03-07RELnone
1U0R crystal structure of mycobacterium tuberculosis nad kinaseRv16952004-07-142004-08-31REL1U0T 1Y3H 1Y3I
2B35 crystal structure of mycobacterium tuberculosis enoyl reductase (inha) inhibited by triclosanRv14842005-09-192006-03-07RELnone
1TQ8 crystal structure of hypothetical protein rv1636 from mycobacterium tuberculosis h37rvRv1636 NYSGXRC:NYSGXRC-T15332004-06-162004-06-29RELnone
2DFT structure of shikimate kinase from mycobacterium tuberculosis complexed with adp and mg at 2.8 angstrons of resolutionRv2539c2006-03-032007-01-16RELnone
1UPI mycobacterium tuberculosis rmlc epimerase (rv3465)Rv34652003-10-052003-10-07RELnone
1N5J crystal structure of mycobacterium tuberculosis thymidylate kinase complexed with thymidine diphosphate (tdp) and thymidine triphosphate (ttp) at ph 5.4 (1.85 a resolution)Rv3247c2002-11-062003-04-15RELnone
2ATW structure of a mycobacterium tuberculosis nusa-rna complexRv2841c2005-08-262005-10-11RELnone
1DQY crystal structure of antigen 85c from mycobacterium tuberculosis with diethyl phosphate inhibitorRv0129c2000-01-052000-07-12REL1DQZ 1VA5
2A86 crystal structure of a pantothenate synthetase complexed with amp and beta-alanineRv3602c2005-07-072006-02-21RELnone
1NBU 7,8-dihydroneopterin aldolase complexed with product from mycobacterium tuberculosisRv3607c2002-12-032004-01-13REL1Z9W
1ME5 crystal structure of mycobacterium tuberculosis alkylperoxidase ahpd h132q mutantRv24292002-08-082002-09-11RELnone
1R88 the crystal structure of mycobacterium tuberculosis mpt51 (fbpc1)Rv3803c2003-10-232003-12-30RELnone
2A6P structure solution to 2.2 angstrom and functional characterisation of the open reading frame rv3214 from mycobacterium tuberculosisRv32142005-07-032006-05-16RELnone
3B4W crystal structure of mycobacterium tuberculosis aldehyde dehydrogenase complexed with nad+Rv0223c2007-10-242007-11-27RELnone
2A87 crystal structure of m. tuberculosis thioredoxin reductaseRv39132005-07-072005-11-29RELnone
2CCD crystal structure of the catalase-peroxidase (katg) and s315t mutant from mycobacterium tuberculosisRv1908C2006-01-162006-01-19RELnone
2H7I crystal structure of mycobacterium tuberculosis enoyl reductase (inha) complexed with 1-cyclohexyl-5-oxo-n-phenylpyrrolidine-3-carboxamideRv14842006-06-022006-10-31RELnone
2VFW rv1086 nativeRv10862007-11-052007-11-13REL2VG0 2VG1 2VG2
2AO2 the 2.07 angstrom crystal structure of mycobacterium tuberculosis chorismate mutase reveals unexpected gene duplication and suggests a role in host-pathogen interactionsRv1885c2005-08-122006-06-13REL2F6L 2FP1 2FP2
1W30 pyrr of mycobacterium tuberculosis as a potential drug targetRv13792004-07-112004-09-29RELnone
2O0T the three dimensional structure of diaminopimelate decarboxylase from mycobacterium tuberculosis reveals a tetrameric enzyme organisationRv12932006-11-282007-02-13RELnone
1MO5 reca-atp-gamma-s-mg complexRv2737c2002-09-072003-02-18RELnone
2IB0 crystal structure of a conserved hypothetical protein, rv2844, from mycobacterium tuberculosisRv2844 ISFI:ISFI1952006-09-082006-09-26RELnone
1Q51 crystal structure of mycobacterium tuberculosis menb in complex with acetoacetyl-coenzyme a, a key enzyme in vitamin k2 biosynthesisRv0548c2003-08-052004-01-27REL1Q52 1RJM 1RJN
2O2H crystal structure of haloalkane dehalogenase rv2579 from mycobacterium tuberculosis complexed with 1,2-dichloroethaneRv25792006-11-292007-11-13REL2O2I
1F8M crystal structure of 3-bromopyruvate modified isocitrate lyase (icl) from mycobacterium tuberculosisRv04672000-06-302000-12-30RELnone
1F0N mycobacterium tuberculosis antigen 85bRv1886c2000-05-162001-01-24REL1F0P
1B1B iron dependent regulatorRv27111998-11-191999-12-03REL1FX7 1U8R
1HTQ multicopy crystallographic structure of a relaxed glutamine synthetase from mycobacterium tuberculosisRv22202001-01-012002-07-24RELnone
2AHB x-ray crystal structure of r46a,r161a mutant of mycobacterium tuberculosis fabhRv0533c2005-07-272005-08-23RELnone
1OY0 the crystal structure of the first enzyme of pantothenate biosynthetic pathway, ketopantoate hydroxymethyltransferase from mycobacterium tuberculosis shows a decameric assembly and terminal helix-swappingRv22252003-04-032003-07-15RELnone
2Z77 x-ray crystal structure of rv0760c from mycobacterium tuberculosis in complex with estradiol-17beta-hemisuccinateRv0760c2007-08-162007-09-18RELnone
1S61 crystal structure of "truncated" hemoglobin n (hbn) from mycobacterium tuberculosis, soaked with butyl-isocyanideRv1542C2004-01-222004-06-29RELnone
1EA1 cytochrome p450 14 alpha-sterol demethylase (cyp51) from mycobacterium tuberculosis in complex with fluconazoleRv0764c2000-11-022000-11-06RELnone
2JD1 x-ray structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase, dxr, rv2870c, from mycobacterium tuberculosis, in complex with manganese and nadphRv2870c2007-01-042007-05-08RELnone
1N40 atomic structure of cyp121, a mycobacterial p450Rv22762002-10-302003-02-04REL1N4G 2IJ7
1P9L structure of m. tuberculosis dihydrodipicolinate reductase in complex with nadh and 2,6 pdcRv2773c2003-05-122003-08-26RELnone
2FHH crystal structure of mycobacterium tuberculosis proteasome in complex with a peptidyl boronate inhibitor mln-273Rv2109c2005-12-232006-02-28RELnone
1MRS crystal structure of mycobacterium tuberculosis thymidylate kinase complexed with 5-ch2oh deoxyuridine monophosphateRv3247c2002-09-182003-01-07RELnone
2Z2I crystal structure of peptidyl-trna hydrolase from mycobacterium tuberculosisRv1014c2007-05-222007-07-24REL2Z2J 2Z2K
2IYU shikimate kinase from mycobacterium tuberculosis in complex with adp, open lid (conf. a)Rv2539c2006-07-222006-10-11RELnone
1ENY crystal structure and function of the isoniazid target of mycobacterium tuberculosisRv14841995-01-271996-01-29RELnone
2G9W crystal structure of rv1846c, a putative transcriptional regulatory protein of mycobacterium tuberculosisRv1846c2006-03-072007-03-13RELnone
2BJB mycobacterium tuberculosis epsp synthase in unliganded stateRv3227 NON-XMTB:rv32272005-02-012006-03-09RELnone
1XVW crystal structure of ahpe from mycobacterium tuberculosis, a 1-cys peroxiredoxinRv2238c2004-10-282005-02-22REL1XXU
2C7G fpra from mycobacterium tuberculosis: his57gln mutantRv31062005-11-242006-07-26RELnone
1N2I crystal structure of pantothenate synthetase from m. tuberculosis in complex with a reaction intermediate, pantoyl adenylate, different occupancies of pantoyl adenylateRv3602c2002-10-222003-04-22RELnone
2JCY x-ray structure of mutant 1-deoxy-d-xylulose 5-phosphate reductoisomerase, dxr, rv2870c, from mycobacterium tuberculosisRv2870c2007-01-042007-05-08RELnone
2QZ8 crystal structure of mycobacterium tuberculosis leucine response regulatory protein (lrpa)Rv3291c2007-08-162007-11-06REL2VBW 2VBX 2VBY 2VBZ 2VC0 2VC1
2B36 crystal structure of mycobacterium tuberculosis enoyl reductase (inha) inhibited by 5-pentyl-2-phenoxyphenolRv14842005-09-192006-03-07RELnone
1S56 crystal structure of "truncated" hemoglobin n (hbn) from mycobacterium tuberculosis, soaked with xe atomsRv1542C2004-01-202004-06-29RELnone
1NXJ structure of rv3853 from mycobacterium tuberculosisRv38532003-02-102003-07-29RELnone
1GN2 s123c mutant of the iron-superoxide dismutase from mycobacterium tuberculosis.Rv38462001-10-022001-10-05REL1GN3 1GN4 1GN6 1IDS
1EYV the crystal structure of nusb from mycobacterium tuberculosisRv2533c2000-05-092000-05-18RELnone
2O2I crystal structure of haloalkane dehalogenase rv2579 from mycobacterium tuberculosis complexed with 1,3-propandiolRv25792006-11-292007-11-13RELnone
1MQ7 crystal structure of dutpase from mycobacterium tuberculosis (rv2697c)Rv2697c2002-09-132002-10-09REL1SIX 1SJN 1SLH 1SM8 1SMC 1SNF
1TPY structure of the cyclopropane synthase mmaa2 from mycobacterium tuberculosisRv0644c2004-06-162004-10-19RELnone
1NFR rv2002 gene product from mycobacterium tuberculosisRv20022002-12-162002-12-30RELnone
1SFR crystal structure of the mycobacterium tuberculosis antigen 85a proteinRv3804c2004-02-202004-07-06RELnone
2G1K crystal structure of mycobacterium tuberculosis shikimate kinase in complex with shikimate at 1.75 angstrom resolutionRv2539c2006-02-142006-07-18RELnone
2Z2J crystal structure of peptidyl-trna hydrolase from mycobacterium tuberculosisRv1014c2007-05-222007-07-24RELnone
1TFU phosphopantetheine adenylyltransferase from mycobacterium tuberculosisRv2965c2004-05-272004-09-14RELnone
2I1U mycobacterium tuberculosis thioredoxin cRv39142006-08-152006-12-19RELnone
1Y8T crystal structure of rv0983 from mycobacterium tuberculosis- proteolytically active formRv09832004-12-132005-01-18RELnone
1L1E crystal structure of mycolic acid cyclopropane synthase pcaa complexed with s-adenosyl-l-homocysteineRv0470c2002-02-152002-03-06RELnone
2O0R the three-dimensional structure of n-succinyldiaminopimelate aminotransferase from mycobacterium tuberculosisRv0858c2006-11-282007-02-27RELnone
2JD2 x-ray structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase, dxr, rv2870c, from mycobacterium tuberculosis, in complex with manganeseRv2870c2007-01-042007-05-08RELnone
2ASF crystal structure of the conserved hypothetical protein rv2074 from mycobacterium tuberculosis 1.6 aRv20742005-08-232005-10-11RELnone
2BCF crystal structure of a evolved putative penicillin-binding protein homolog, rv2911, from mycobacterium tuberculosis.Rv29112005-10-192005-10-25RELnone
1RJN the crystal structure of menb (rv0548c) from mycobacterium tuberculosis in complex with the coa portion of naphthoyl coaRv0548c2003-11-192004-11-30RELnone
2IYV shikimate kinase from mycobacterium tuberculosis in complex with adp, open lid (conf. b)Rv2539c2006-07-222006-10-11RELnone
1ENZ crystal structure and function of the isoniazid target of mycobacterium tuberculosisRv14841995-01-271996-01-29RELnone
1XXO x-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase at 1.8 a resolutionRv11552004-11-072004-11-16RELnone
1YLK crystal structure of rv1284 from mycobacterium tuberculosis in complex with thiocyanateRv1284 NON-SPINE:Rv12842005-01-192005-03-08RELnone
1YS3 crystal structure of the atp binding domain of prrb from mycobacterium tuberculosisRv0902c NON-XMTB:rv0902c2005-02-072005-07-12REL1YSR
2BM6 the structure of mfpa (rv3361c, c2221 crystal form). the pentapeptide repeat protein from mycobacterium tuberculosis folds as a right- handed quadrilateral beta-helix.Rv3361c2005-03-092005-06-07RELnone
1RQ2 mycobacterium tuberculosis ftsz in complex with citrateRv2150c2003-12-042004-08-31RELnone
1P45 targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural dataRv14842003-04-212003-09-16RELnone
1N2J crystal structure of a pantothenate synthetase from m. tuberculosis in complex with pantoateRv3602c2002-10-222003-04-22RELnone
1Y3H crystal structure of inorganic polyphosphate/atp-nad kinase from mycobacterium tuberculosisRv16952004-11-242005-01-18RELnone
2A84 crystal structure of a pantothenate synthetase complexed with atpRv3602c2005-07-072006-02-21RELnone
1IDS x-ray structure analysis of the iron-dependent superoxide dismutase from mycobacterium tuberculosis at 2.0 angstroms resolutions reveals novel dimer-dimer interactionsRv38461994-09-291994-12-20RELnone
1Y0H structure of rv0793 from mycobacterium tuberculosisRv07932004-11-152004-12-28RELnone
2CIG dihydrofolate reductase from mycobacterium tuberculosis inhibited by the acyclic 4r isomer of inh-nadp a derivative of the prodrug isoniazid.Rv2763c2006-03-202006-04-25RELnone
1YS6 crystal structure of the response regulatory protein prra from mycobacterium tuberculosisRv0903c NON-XMTB:rv0903c2005-02-072006-02-07REL1YS7
2I6Y structure and mechanism of mycobacterium tuberculosis salicylate synthase, mbtiRv2386c2006-08-292007-06-19RELnone
1HKW mycobacterium diaminopimelate dicarboxylase (lysa)Rv12932003-03-112003-03-18RELnone
1ZVW the crystal structure of trpd (rv2192c) from mycobacterium tuberculosis in complex with prpp and magnesiumRv2192c2005-06-022006-01-17REL2BPQ
2FR2 crystal structure of rv2717c from m. tuberculosisRv2717c2006-01-182006-01-31RELnone
1Y30 x-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase complexed with flavin mononucleotide at 2.2 a resolutionRv11552004-11-232005-08-30RELnone
2AQ8 crystal structure of wild-type of enoyl-acp(coa) reductase from mycobacterium tuberculosis in complex with nadh.Rv14842005-08-172006-05-23RELnone
1QPR quinolinate phosphoribosyltransferase (qaprtase) from mycobacterium tuberculosis in complex with phthalate and prpcpRv15961998-10-171998-10-21RELnone
1NH7 atp phosphoribosyltransferase (atp-prtase) from mycobacterium tuberculosisRv2121c2002-12-182003-02-11REL1NH8
1Q52 crystal structure of mycobacterium tuberculosis menb, a key enzyme in vitamin k2 biosynthesisRv0548c2003-08-052004-01-27RELnone
1N5L crystal structure of mycobacterium tuberculosis thymidylate kinase crystallized in sodium malonate, after catalysis in the crystal (2.3 a resolution)Rv3247c2002-11-062003-04-15RELnone
1U9O crystal structure of the transcriptional regulator ethr in a ligand bound conformationRv38552004-08-102004-11-16RELnone
1C3V dihydrodipicolinate reductase from mycobacterium tuberculosis complexed with nadph and pdcRv2773c1999-07-282003-08-26REL1P9L 1YL5 1YL6 1YL7
1MRU intracellular ser/thr protein kinase domain of mycobacterium tuberculosis pknb.Rv0014c2002-09-182003-02-11REL1O6Y
2VG2 rv2361 with ippRv10862007-11-072007-11-13RELnone
2GEV pantothenate kinase from mycobacterium tuberculosis (mtpank) in complex with a coenzyme a derivative, form-ii (lt)Rv1092c2006-03-202006-06-06RELnone
1GU9 crystal structure of mycobacterium tuberculosis alkylperoxidase ahpdRv24292002-01-242002-02-14REL1KNC 1LW1 1ME5
1DG8 dihydrofolate reductase of mycobacterium tuberculosis complexed with nadphRv2763c1999-11-232000-03-09RELnone
1I9G crystal structure of an adomet dependent methyltransferaseRv2118c2001-03-202001-09-26RELnone
2IYS shikimate kinase from mycobacterium tuberculosis in complex with shikimate, open lid (conf. a)Rv2539c2006-07-212006-10-11RELnone
1G2O crystal structure of purine nucleoside phosphorylase from mycobacterium tuberculosis in complex with a transition-state inhibitorRv33072000-10-202001-08-01REL1I80 1N3I
2IYR shikimate kinase from mycobacterium tuberculosis in complex with shikimateRv2539c2006-07-212006-10-11RELnone
1ZID long fatty acid chain enoyl-acp reductase (inha) in complex with an isonicotinic-acyl-nadh inhibitorRv14841997-03-251998-03-25RELnone
2BM7 the structure of mfpa (rv3361c, p3221 crystal form). the pentapeptide repeat protein from mycobacterium tuberculosis folds as a right- handed quadrilateral beta-helix.Rv3361c2005-03-092005-06-07RELnone
1YL6 crystal structure of mycobacterium tuberculosis dihydrodipicolinate reductase (rv2773c) (crystal form b)Rv2773c NON-XMTB:rv2773c2005-01-192006-01-17RELnone
1F0P mycobacterium tuberculosis antigen 85b with trehaloseRv1886c2000-05-162001-01-24RELnone
1SIX mycobacterium tuberculosis dutpase complexed with magnesium and alpha,beta-imido-dutpRv2697c2004-03-012004-03-09RELnone
1U0T crystal structure of mycobacterium tuberculosis nad kinaseRv16952004-07-142004-08-31RELnone
2GDN crystal structure of the mycobacterium tuberculosis beta-lactamaseRv2068c2006-03-162006-04-18RELnone
1KNC structure of ahpd from mycobacterium tuberculosis, a novel enzyme with thioredoxin-like activity.Rv24292001-12-182002-01-23RELnone
1KPH crystal structure of mycolic acid cyclopropane synthase cmaa1 complexed with sah and dddmabRv3392c2001-12-302002-01-11RELnone
1MO3 reca-adp complexRv2737c2002-09-072003-02-18RELnone
2PKK crystal structure of m tuberculosis adenosine kinase complexed with 2-fluro adenosineRV2202c2007-04-172007-06-19RELnone
1GR0 myo-inositol 1-phosphate synthase from mycobacterium tuberculosis in complex with nad and zinc.Rv0046c2001-12-102002-03-12RELnone
1RJM crystal structure of menb (rv0548c) from mycobacterium tuberculosisRv0548c2003-11-192004-11-30RELnone
1L4Y crystal structure of shikimate kinase from mycobacterium tuberculosis in complex with mgadp at 2.0 angstrom resolutionRv2539c2002-03-062002-06-12RELnone
1XXU crystal structure of ahpe from mycrobacterium tuberculosis, a 1-cys peroxiredoxinRv2238c2004-11-082005-02-22RELnone
1W9A crystal structure of rv1155 from mycobacterium tuberculosisRv11552004-10-072005-01-06REL1XXO 1Y30 2AQ6
1UE7 crystal structure of the single-stranded dna-binding protein from mycobacterium tuberculosisRv00542003-05-092004-02-10RELnone
2JCZ x-ray structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase, dxr, rv2870c, from mycobacterium tuberculosis, in complex with fosmidomycin, manganese and nadphRv2870c2007-01-042007-05-08RELnone
1K0R crystal structure of mycobacterium tuberculosis nusaRv2841c2001-09-202001-12-21REL2ASB 2ATW
1LW1 crystal structure of mycobacterium tuberculosis alkylperoxidase ahpd h137f mutantRv24292002-05-302002-07-17RELnone
1LU4 1.1 angstrom resolution crystal structure of a secreted mycobacterium tuberculosis disulfide oxidoreductase homologous to e. coli dsbe: implications for functionsRv2878c2002-05-212003-10-14RELnone
1SJN mycobacterium tuberculosis dutpase complexed with magnesium and alpha,beta-imido-dutpRv2697c2004-03-042004-03-09RELnone
1UE6 crystal structure of the single-stranded dna-binding protein from mycobacterium tuberculosisRv00542003-05-092004-02-10RELnone
1VA5 antigen 85c with octylthioglucoside in active siteRv0129c2004-02-112004-07-06RELnone
1HKV mycobacterium diaminopimelate dicarboxylase (lysa)Rv12932003-03-112003-03-20REL1HKW 2O0T
1NWA structure of mycobacterium tuberculosis methionine sulfoxide reductase a in complex with protein-bound methionineRv0137c2003-02-052003-07-08RELnone
1SD5 crystal structure of rv1626Rv1626 NON-XMTB:rv16262004-02-132004-09-21RELnone
1RWI extracellular domain of mycobacterium tuberculosis pkndRv0931c2003-12-162004-04-27REL1RWL
1RWL extracellular domain of mycobacterium tuberculosis pkndRv0931c2003-12-162004-04-27RELnone
1UOZ structure of the endoglucanase cel6 from mycobacterium tuberculosis in complex with thiocellopentaose at 1.1 angstromRv00622003-09-262004-11-18REL1UP0 1UP2 1UP3
1Y3I crystal structure of mycobacterium tuberculosis nad kinase-nad complexRv16952004-11-252005-01-18RELnone
2E3J the crystal structure of epoxide hydrolase b (rv1938) from mycobacterium tuberculosis at 2.1 angstromRv19382006-11-272007-12-04RELnone
1MO6 reca-datp-mg complexRv2737c2002-09-072003-02-18RELnone
2AF6 crystal structure of mycobacterium tuberculosis flavin dependent thymidylate synthase (mtb thyx) in the presence of co-factor fad and substrate analog 5-bromo-2'-deoxyuridine-5'-monophosphate (brdump)Rv2754c2005-07-252005-10-04REL2GQ2
2GET pantothenate kinase from mycobacterium tuberculosis (mtpank) in complex with a coenzyme a derivative, form-i (lt)Rv1092c2006-03-202006-06-06RELnone
2A11 crystal structure of nuclease domain of ribonuclase iii from mycobacterium tuberculosisRv2925c2005-06-172005-07-05RELnone
1G19 structure of reca proteinRv2737c2000-10-112000-12-11RELnone
1W2G crystal structure of mycobacterium tuberculosis thymidylate kinase complexed with deoxythymidine (dt) (2.1 a resolution)Rv3247c2004-07-062005-01-12RELnone
1UE1 crystal structure of the single-stranded dna-binding protein from mycobacterium tuberculosisRv00542003-05-082004-02-10REL1UE5 1UE6 1UE7
1H5Z cytochrome p450 14 alpha-sterol demethylase (cyp51) from mycobacterium tuberculosis in ferric low-spin stateRv0764c2001-05-312003-10-03RELnone
1NGK crystallographic structure of mycobacterium tuberculosis hemoglobin oRv24702002-12-172003-05-20RELnone
1NH8 atp phosphoribosyltransferase (atp-prtase) from mycobacterium tuberculosis in complex with amp and histidineRv2121c2002-12-182003-02-11RELnone
1ZYU crystal structure of mycobacterium tuberculosis shikimate kinase in complex with shikimate and amppcp at 2.85 angstrom resolutionRv2539c2005-06-112006-07-11RELnone
1QPO quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from mycobacterium tuberculosisRv15961998-11-211998-11-24RELnone
2IYT shikimate kinase from mycobacterium tuberculosis in unliganded state, open lid (conf. a)Rv2539c2006-07-222006-10-11RELnone
1U5H structure of citrate lyase beta subunit from mycobacterium tuberculosisRv2498c2004-07-272004-10-12REL1U5V 1Z6K
1RQ7 mycobacterium tuberculosis ftsz in complex with gdpRv2150c2003-12-042004-08-31RELnone
1DF7 dihydrofolate reductase of mycobacterium tuberculosis complexed with nadph and methotrexateRv2763c1999-11-172000-03-09REL1DG5 1DG7 1DG8 2CIG
1O6Y catalytic domain of pknb kinase from mycobacterium tuberculosisRv0014c NON-SPINE:IPRv0014cPALZ2002-10-212003-01-30RELnone
1ZA0 x-ray structure of putative acyl-acp desaturase desa2 from mycobacterium tuberculosis h37rvRv10942005-04-052005-06-07RELnone
2BYO crystal structure of mycobacterium tuberculosis lipoprotein lppx ( rv2945c)Rv2945c2005-08-032006-03-22RELnone
1I80 crystal structure of m. tuberculosis pnp in complex with iminoribitol, 9-deazahypoxanthine and phosphate ionRv33072001-03-122001-08-01RELnone
1LMI 1.5 angstrom resolution crystal structure of a secreted protein from mycobacterium tuberculosis-mpt63Rv1926c2002-05-012002-12-04RELnone
2BZ9 ligand-free structure of sterol 14alpha-demethylase from mycobacterium tuberculosis in p2(1) space groupRv0764c2005-08-122006-12-07RELnone
1YK9 crystal structure of a mutant form of the mycobacterial adenylyl cyclase rv1625cRv1625c2005-01-172006-01-24RELnone
2G85 crystal structure of chorismate synthase from mycobacterium tuberculosis at 2.22 angstrons of resolutionRv2540c2006-03-012007-03-01RELnone
1GN4 h145e mutant of mycobacterium tuberculosis iron-superoxide dismutase.Rv38462001-10-022001-10-05RELnone
2BPQ anthranilate phosphoribosyltransferase (trpd) from mycobacterium tuberculosis (apo structure)Rv2192c2005-04-222006-01-04RELnone
2GES pantothenate kinase from mycobacterium tuberculosis (mtpank) in complex with a coenzyme a derivative, form-i (rt)Rv1092c2006-03-202006-06-06REL2GET 2GEU 2GEV
2GL3 crystal structure of mycobacterium tuberculosis trhbn, tyrb10phe glne11val mutantRv1542C2006-04-042006-09-19RELnone
2VG1 rv1086 e,e-farnesyl diphosphate complexRv10862007-11-072007-11-13RELnone
2B70 t4 lysozyme mutant l99a at ambient pressureRv2178c2005-10-032005-11-08REL2B7O
1N5I crystal structure of inactive mycobacterium tuberculosis thymidylate kinase complexed with thymidine monophosphate (tmp) at ph 4.6 (resolution 1.85 a)Rv3247c2002-11-062003-04-08RELnone
2AJ9 x-ray crystal structure of w42a,r161a double mutant of mycobacterium tuberculosis beta-ketoacyl-acp synthase iiiRv0533c2005-08-012005-08-30RELnone
1N3I crystal structure of mycobacterium tuberculosis pnp with transition state analog dadme-immhRv33072002-10-282003-09-30RELnone
1G3U crystal structure of mycobacterium tuberculosis thymidylate kinase complexed with thymidine monophosphate (tmp)Rv3247c2000-10-252001-10-25REL1GSI 1GTV 1MRN 1MRS 1N5I 1N5J 1N5K 1N5L 1W2G 1W2H
2Z7A x-ray crystal structure of rv0760c from mycobacterium tuberculosis at 2.10 angstrom resolutionRv0760c2007-08-172007-09-11RELnone

Note 1:  Last updated: Jul 2 2009

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Sequence Redundancy Statistics

Table 5: Sequence Redundancy Statistics for TB by Experimental Status

Sequence Identity(%)Novel Targets
Status:
Selected
Novel Targets
Status:
Cloned
Novel Targets
Status:
Expressed
Novel Targets
Status:
Purified
Novel Targets
Status:
Crystallized
Novel Targets
Status:
Crystal Structure
Novel Targets
Status:
NMR Structure
Novel Targets
Status:
in PDB
<10017431281971472334234208208
<9017381277969472334234208208
<7017181261962468330231205205
<5016251191928454322228203203
<301131955797425304214194191
Last updated: 09-04-28
Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in TargetDB which are in the same experimental status category and at least 20 amino acids long

Table 6:Sequence Redundancy Statistics for Structures Released by TB by Year

Year Released Structures Number of Released Structures <30% Identity at Time of Release Percent(%) of Released Structures <30% Identity(%) at Time of Release
<= 200025416
20011616
200228311
2003461226
2004691116
2005631930
2006881113
20074649
200811100
Total3826617
Last updated:09-07-02
Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity.   Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings.  Sequence redundancy calculations are based on comparison to all protein sequences in the PDB which are at least 20 amino acids long
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